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个人简介

2021/11-至今:化学系常务副系主任 2017/08-2021/11:化学系副系主任 2015/01-至今:浙江大学化学系 教授、博导、独立PI 2010/4-2014/12:浙江大学化学系特聘研究员 、博导、独立PI 2007/08-2010/4:研究助理,The Scripps Research Institute化学系 (导师:Prof. Jin-Quan Yu) 2006/10-2007/08:博士后,加州大学圣迭戈分校化学系 (导师:Prof. Michael S. VanNieuwenhze) 2001/09-2006/07:博士,中科院上海有机所生命有机国家重点实验室 (导师: 俞飚院士) 1997/09-2001/07:学士,南开大学化学系 (导师:孟继本教授)

研究领域

1.过渡金属催化的碳氢键活化 2.天然产物多样性合成及其化学生物学研究

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Jiang, A.-L.; Zhou, G.; Jiang, B.-Y.; Zhou, T.;* Xu, X.-T.;* Shi, B.-F.* “Pd-Catalyzed Atroposelective C–H Olefination: Diverse Synthesis of Axially Chiral Biaryl-2-carboxylic Acids”Org. Lett. 2024. Teng, M.-Y.; Liu, D.-Y.;† Mao, S.-Y.;† Wu, X.; Chen, J.-H.; Zhong, M.-Y.; Huang, F.-R.; Yao, Q.-J.;* Shi, B.-F.* “Asymmetric Dearomatization of Indoles through Cobalt-Catalyzed Enantioselective C−H Functionalization Enabled by Photocatalysis”Angew. Chem. Int. Ed. 2024. Jin, L.;† Li, Y.;† Mao, Y.;† He, X.-B.; Lu, Z.; Zhang, Q.;* Shi, B.-F.* “Chiral dinitrogen ligand enabled asymmetric Pd/norbornene cooperative catalysis toward the assembly of C–N axially chiral scaffolds”Nat. Commun. 2024, 15, 4908. Wu, L.-S.; Zhou, T.;* Shi, B.-F.* “Pd(II)-Catalyzed Desymmetrizing gem-Dimethyl C(sp3)–H Alkenylation/Aza-Wacker Cyclization Directed by PIP Auxiliary”Org. Lett. 2024, 26, 4457–4462 Jiang, B.; Zhou, G.; Jiang, A.-L.; Zhou, T.;* Shi, B.-F.* “Synthesis of Axially Chiral Biaryl-2-Carboxamides through Pd(II)-Catalyzed Atroposelective C−H Olefination”Org. Chem. Front. 2024. Wang, C.-Y.; Zhou, T.;* Shi, B.-F.* “Pd(II)-Catalyzed Enantioselective C(sp3)–H Arylation toward P-Stereogenic Dialkylphosphinamides” ACS Catal. 2024, 14, 7213–7219 Huang, F.-R.; Yao, Q.-J.;* Zhang, P.; Teng, M.-Y.; Chen, J.-H.; Jiang, L.-C.; Shi, B.-F.* “Cobalt-Catalyzed Domino Transformations via Enantioselective C–H Activation/Nucleophilic [3+2] Annulation Towards Chiral Bridged Bicycles” ChemRxiv. 2024, 10.26434/chemrxiv-2024-7j0wl Huang, F.-R.; Zhang, P.; Yao, Q.-J.;* Shi, B.-F.* “Construction of Planar Chiral Ferrocenes by Cobalt-Catalyzed Enantioselective C-H Acyloxylation Enabled by Dual Ligand” CCS Chem. 2024, doi.org/10.31635/ccschem.024.202303709 Zhou, G.;† Zhou, T.;†* Jiang, A.-L.; Qian, P.-F.; Li, J.-Y.; Jiang, B.-Y.; Chen, Z.-J.; Shi, B.-F.* “Electrooxidative Rhodium(III)/Chiral Carboxylic Acid-Catalyzed Enantioselective C‒H Annulation of Sulfoximines with Alkynes” Angew. Chem. Int. Ed. 2024, doi.org/10.1002/anie.202319871 Chen, Z.-J.;† Fan, L.-J.;† Xie, P.-P.; Qian, P.-F.; Hu, X.; Zhou, T.;* Shi, B.-F.* “Pd(II)-Catalyzed Enantioselective C–H Olefination toward the Synthesis of P‑stereogenic Phosphinamides”Chem. Commun. 2024, Accepted Teng, M.-Y.; Wu, Y.-J.; Chen, J.-H.; Huang, F.-R.; Liu, D.-Y.; Yao, Q.-J.;* Shi, B.-F.* “Cobalt-Catalyzed Enantioselective C−H Carbonylation towards Chiral Isoindolinones”Angew. Chem. Int. Ed. 2024, doi.org/10.1002/anie.202318803 Han, Y.-Q.; Shi, B.-F.* “Palladium(II)-Catalyzed Enantioselective Functionalization of C(sp3)—H Bonds” Acta Chim. Sinica 2023, 81, 1522–1540 Wu, Y.-J.;† Chen, J.-H.;† Teng, M.-Y.; Li, X. (20级本科生); Jiang, T.-Y. (19级本科生); Huang, F.-R.; Yao, Q.-J.;* Shi, B.-F.* “Cobalt-Catalyzed Enantioselective C–H Annulation of Benzylamines with Alkynes: Application to the Modular and Asymmetric Syntheses of Bioactive Molecules” J. Am. Chem. Soc. 2023, Accepted Jiang, T.-Y. (19级本科生); Ke, Y.-T. (19级本科生); Wu, Y.-J.; Yao, Q.-J.;* Shi, B.-F.* “Pd(II)-Catalyzed atroposelective C−H olefination: synthesis of enantioenriched N-aryl peptoid atropisomers”Chem. Commun. 2023, Qian, P.-F.; Zhou, T.;* Shi, B.-F.*“Transition-metal-catalyzed atroposelective synthesis of axially chiral styrenes”Chem. Commun. 2023, 59, 12669–12684 Qian, P.-F.; Li, J.-Y.; Zhou, Y.-B.; Zhou, T.;* Shi, B.-F.*“Half-Sandwich d6-Metal (CoIII, RhIII, IrIII, RuII)-Catalyzed Enantioselective C–H Activation”SynOpen 2023, 7, 466–485 Wu, Y.-J.; Wang, Z.-K.; Jia, Z.-S.; Chen, J.-H.; Huang, F.-R.; Zhan, B.-B.; Yao, Q.-J.;* Shi, B.-F.*“Synthesis of Axially Chiral Biaryls through Cobalt(II)-Catalyzed Atroposelective C−H Arylation”Angew. Chem. Int. Ed. 2023, 10.1002/anie.202310004 Zhou, T.;* Fan, L.-J.; Chen, Z.-J.; Jiang, M.-X.; Qian, P.-F.; Hu, X.; Zhang, K.;* Shi, B.-F.*“Synthesis of P-Stereogenic Phosphinamides via Pd(II)-Catalyzed Enantioselective C–H Alkynylation”Org. Lett. 2023, 25, 5724 Chen, J.-H.; Shi, B.-F.*"O-Allylhydroxyamine: a Bifunctional Olefin for Construction of Axially and Centrally Chiral Amino Alcohols via Asymmetric Carboamidation" Chin. J. Org. Chem 2023, 43, 2252-2253 Wang, L.†; Yuan, W.-K.†; Wang, Z.-K.; Luo, J.; Zhou, T.;* Shi, B.-F.*“Synthesis of C−N Axial Chirality N−Arylindoles via Pd(II)-Catalyzed Free Amine-Directed Atroposelective C−H Olefination”Chin. J. Chem. 2023, 10.1002/cjoc.202300355 Zhang, Z.-Z.*; Jiang, L.; Li, J.-L.; Shi, B.-F.“Highly Stereoselective Synthesis of Bis-C-ferrocenyl Glycosides via Palladium-Catalyzed Directed C–H Glycosylation”Org. Lett. 2023, 25, 4070 Wang, Z.-K.; Wu, Y.-J.; Yao, Q.-J.;* Shi, B.-F.*“Synthesis of Chiral Diarylmethylamines by Cobalt-Catalyzed Enantioselective C-H Alkoxylation”Angew. Chem. Int. Ed. 2023, 62, e202304706 Zhou, G.; Chen, J.-H.; Yao, Q.-J.; Huang, F.-R.; Wang, Z.-K.; Shi, B.-F.* “Base-Promoted Electrochemical Co(II)-Catalyzed Enantioselective C-H Oxygenation” Angew. Chem. Int. Ed. 2023, 62, e202302964 Yao, Q.-J.; Huang, F.-R.; Chen, J.-H.; Zhong, M.-Y. (19级本科生); Shi, B.-F.* “Enantio- and Regioselective Electrooxidative Cobalt-Catalyzed C−H/N–H Annulation with Alkenes” Angew. Chem. Int. Ed. 2023, 62, DOI: 10.1002/anie.202218533 Shi, B.-F.; Chen, Y.; Geng, M.; Zhu, D.;* Yu, B.* “Total Synthesis of Starfish Cyclic Steroid Glycosides. Part 1, Synthesis of the Aglycone and Attempts at Installation of the Sugar Units”Chin. J. Chem. 2023, DOI: 10.1002/cjoc.202200784 Qian, P.-F.(18级本科生)†; Zhou, T.†,*; Li, J.-Y.(18级本科生); Zhou, Y.-B.(18级本科生); Shi, B.-F.*“Ru(II)/Chiral Carboxylic Acid-Catalyzed Asymmetric [4 + 3] Annulation of Sulfoximines with α,β-Unsaturated Ketones” ACS Catal. 2022, 12, 13876-13883 Liu, M.; Sun, J.†; Zhang, T.†; Ding, Y.; Han, Y.-Q.; Martín-Montero, R.; Lan, Y.;* Shi, B.-F.;* Engle, K. M.* “Regio- and Stereoselective 1,2-Oxyhalogenation of Non-Conjugated Alkynes via Directed Nucleopalladation: Catalytic Access to Tetrasubstituted Alkenes”Angew. Chem. Int. Ed. 2022, 61, e202209099 Wang, B.-J.; Xu, G.-X.; Huang, Z.-W.; Wu, X.; Hong, X.;* Yao, Q.-J. ;* Shi, B.-F.* 'Single-Step Synthesis of Atropisomers with Vicinal C–C and C–N Diaxes by Cobalt-Catalyzed Atroposelective C–H Annulation' Angew. Chem. Int. Ed. 2022, DOI: 10.1002/anie.202208912 Chen, J.-H.; Teng, M.-Y.; Huang, F.-R.; Song, H.; Wang, Z.-K.; Zhuang, H.-L.(21级本科生); Wu, Y.-J.; Wu, X.; Yao, Q.-J. ;* Shi, B.-F.* 'Cobalt/Salox-Catalyzed Enantioselective Dehydrogenative C–H Alkoxylation and Amination' Angew. Chem. Int. Ed. 2022, DOI: 10.1002/anie.202210106 Zhou, Y.-B. (18级本科生);† Zhou, T.;†,* Qian, P.-F. (18级本科生生); Li, J.-Y. (18级本科生); Shi, B.-F.*'Synthesis of Sulfur-Stereogenic Sulfoximines via Co(III)/Chiral Carboxylic Acid-Catalyzed Enantioselective C–H Amidation'ACS Catal. 2022, 12, 9806-9811 Yue, Q.; Liu, B.; Liao, G.;* Shi, B.-F.*'Binaphthyl Scaffold: A Class of Versatile Structure in Asymmetric C–H Functionalization'ACS Catal. 2022, 12, 9359-9396 Yao, Q.-J.; Chen, J.-H.; Song, H.; Huang, F.-R.; Shi, B.-F.*'Cobalt/Salox-Catalyzed Enantioselective C-H Functionalization of Arylphosphinamides'Angew. Chem. Int. Ed. 2022, e202202892 (PDF, Invited Review for 'Asymmetric C-H Functionalization' Special Topic). Qian, P.-F. (18级本科生);† Li, J.-Y. (18级本科生);† Zhou, T.;* Shi, B.-F.*'Synthesis of P- and S-Stereogenic Compounds via Enantioselective C-H Functionalization'Synthesis 2022, DOI: 10.1055/a-1802-6793 Zhang, Z.-Z.;* Li, Y.; Shi, B.-F.*'Cp*Rh(III)-Catalyzed and Solvent-Controlled Tunable [4+1]/[4+3] Annulation for the Divergent Assembly of Dihydrobenzo[cd]indoles and Dihydronaphtho[1,8-bc]azepines'Org. Chem. Front. 2022, 9, 3262-3267 . Zhang, Z.-Z.;* Huang, D.-Y.; Shi, B.-F.*'Recent Advances in Synthesis of Ferrocene Derivatives via 3d Transition Metal-Catalyzed C-H Functionalization'Org. Biomol. Chem. 2022, 20, 4061-4073 Zhang, Q.; Wu, L.-S.; Shi, B.-F.* 'Forging C-Heteroatom Bonds by Transition Metal-Catalyzed Enantioselective C-H Functionalization' Chem 2022, 8, 1-30 Liao, G.;† Zhang, T.;† Jin, L.;†Wang, B.-J.; Xu, C.-K.; Lan, Y.;* Zhao, Y.;* Shi, B.-F.* 'Experimental and Computational Studies on the Directing Ability of Chalcogenoethers in Palladium-Catalyzed Atroposelective C–H Olefination and Allylation' Angew. Chem. Int. Ed. 2022, DOI: 10.1002/anie.202115221 Zhan, B.-B.; Jin, L.; Shi, B.-F.* 'Palladium-Catalyzed Enantioselective C-H Functionalization via C-H Palladation' Trends in Chem. 2022, DOI: 10.1016/j.trechm.2021.12.005 Wu, Y.-J.; Liao, G.; Shi, B.-F.* 'Stereoselective Construction of Atropisomers Featuring a C-N Chiral Axis' Green Synth. Catal. 2022, DOI: 10.1016/j.gresc.2021.12.005. Jia, Z.-S.;† Wu, Y.-J.;† Yao, Q.-J.;* Xu, X.-T.;* Zhang, K.;* Shi, B.-F.* 'Pd(II)-Catalyzed Atroposelective C-H Allylation: Synthesis of Enantioenriched N-Aryl Peptoid Atropisomers' Org. Lett. 2022, DOI: 10.1021/acs.orglett.1c03967 Yu, X.;† Zhang, Z.-Z.;† Niu, J.-L.;* Shi, B.-F.* 'Coordination-Assisted, Transition-Metal-Catalyzed Enantioselective Desymmetric C-H Functionalization' Org. Chem. Front. 2022, DOI: 10.1039/D1QO01884A Liu, Y.-H.;† Xie, P.-P.;† Liu, L.; Fan, J.; Zhang, Z.-Z.; Hong, X.;* Shi, B.-F.* 'Cp*Co(III)-Catalyzed Enantioselective Hydroarylation of Unactivated Terminal Alkenes via C-H Activation' J. Am. Chem. Soc. 2021, 143, 19112-19120 Liu, B.;† Romine, A. M.;† Rubel, C. Z.; Engle, K.;* Shi, B.-F.* 'Transition-Metal-Catalyzed, Coordination-Assisted Functionalization of Nonactivated C(sp3)-H Bonds' Chem. Rev. 2021, 121, 14957-15074

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