Schorey , Jeff - University of Notre Dame

个人简介

George B. Craig Jr. Professor of Biological Sciences 2014 - present Professor, Department of Biological Sciences, University of Notre Dame 2010 – present Associate Professor, Department of Biological Sciences, University of Notre Dame 2004 – 2010 Assistant Professor, Department of Biological Sciences, University of Notre Dame 1998 – 2004 Instructor of Medicine, Washington University School of Medicine, St. Louis, MO. 1996 – 1998 Post-Doctoral Fellow, Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO. 1993 – 1996 Ph.D., University of Texas Health Science Center, San Antonio Texas 1992

研究领域

Cellular & Moleculular Biology Microbiology & Immunology Infectious & Vector-Borne Diseases

近期论文

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Smith V.L., Jackson, L. and Schorey, J.S. (2015) Ubiquitination as a mechanism to transport soluble mycobacterial and eukaryotic proteins to exosomes. J. Immunol. 195(6):2722-30. Schorey J.S., Cheng Y., Singh P.P., Smith V.L., (2015) Exosomes and other extracellular vesicles in host-pathogen interactions. EMBO Rep. 16(1):24-43. Singh, P.P., *Li, L. and Schorey, J.S. (2015). Exosomal RNA from Mycobacterium tuberculosis infected cells is functional in recipient macrophages. Traffic. 16(6) 555-571. Kruh-Garcia NA, Wolfe LM, Chaisson LH, Worodria WO, Nahid P, Schorey JS, Davis JL, Dobos KM (2014) Detection of Mycobacterium tuberculosis Peptides in the Exosomes of Patients with Active and Latent M. tuberculosis Infection Using MRM-MS. PLoS One. 9(7):e103811. Cheng, Y. Moraski, G.C. Cramer, J. Miller, M.J. and Schorey, J.S. (2014) Bactericidal Activity of an Imidazo[1, 2-a]pyridine Using a Mouse M. tuberculosis Infection Model. PLoS ONE, 9(1) e87483. Cheng, Y. and Schorey, J.S. (2013) Exosomes carrying mycobacterial antigens can protect mice against an M. tuberculosis Infection. European Journal of Immunology. 43 (12) 3279-3290. Giri, P.K., Kruh, N.A., Dobos, K.M. and Schorey, J.S. (2010) Proteomic analysis identifies highly antigenic proteins on exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages. Proteomics. 10; 3190-3202. Yadav, M. and Schorey, J.S. (2006) The β-glucan receptor Dectin-1 functions together with TLR2 to mediate macrophage activation by mycobacteria. Blood. 108; 3168-3175. Krzywinska, E., Bhatnagar, S., *Sweet, L., Chatterjee, D. and Schorey, J.S. (2005) Modification of Mycobacterium avium glycopeptidolipid structure results in bacilli of attenuated virulence. Molecular Microbiology. 56; 1262-1273. Kelley, V.A. and Schorey, J.S. (2003) Endosome Fusion and Iron Acquisition is Required for Mycobacterial Retention in an Early Phagosomal Compartment in Primary Macrophages. Molecular Biology of the Cell. 14; 3366-77. Bohlson, S.S., Strasser, J.A., Bower, J.J., and Schorey, J.S. (2001) The role of complement in Mycobacterium avium pathogenesis: In vivo and in vitro analysis of the host response to infection in the absence of complement component C3. Infection & Immunity. 69; 7729-7735. Schorey, J.S., Carroll, M.C. and Brown, E.J. (1997) A macrophage invasion mechanism of pathogenic mycobacteria. Science. 277; 1091-1093.