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个人简介

B.A. Biology, Emmanuel College, Boston, MA, 1976 Ph.D., Molecular Biology, Brown University, Providence, RI, 1982 Postdoc, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1982-1984 Postdoc, University of Virginia School of Medicine, Charlottesville, VA, 1984-1986

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Karki, A., Humphrey, S. E., Steele, R. E., Hess, D. A., Taparowsky, E. J., and Konieczny, S. F. 2015. Silencing Mist1 gene expression is essential for recovery from acute pancreatitis. PLoS One 10:e0145724. Kim, M. H., Taparowsky, E. J., and Kim, C. H. 2015. Retinoic acid differentially regulates the migration of innate lymphoid cell subsets to the gut. Immunity 43:107-119. Yao, S., Buzo, B. F., Pham, D., Jiang, L., Taparowsky, E. J., Kaplan, M. H., and Sun, J. 2013. Interferon regulatory factor 4 sustains CD8+ T cell expansion and effector differentiation. Immunity 39:833-845. Jabeen, R., Goswami, R., Awe, O., Kulkarni, A., Nguyen, E. T., Attenasio, A., Walsh, D., Olson, M. R., Kim, M. H., Tepper, R. S., Sun, J., Kim, C. H., Taparaowsky, E. J., Zhou, B., and Kaplan, M. H. 2013. Th9 cell development requires a BATF-regulated transcriptional network. J. Clin. Invest. 123:4641-4653. Jordan-Williams, K. L., Poston, S., and Taparowsky, E. J. 2013. BATF regulates the development and function of IL-17 producing iNKT cells. BMC Immunol. 14:16. doi: 10.1186/1471-2172-14-16. Wang, C., Thangamani, S., Kim, M., Gu, B.-H., Lee, J. H., Taparowsky, E. J. and Kim, C. H. 2013. BATF is required for normal expression of gut-homing receptors by T helper cells in response to retinoic acid. J. Exp. Med. 210:475-489. Xiao, X., Balasubramanian, S., Liu, W., Chu, X., Wang, H., Taparowsky, E. J., Fu, Y.-X., Choi, Y., Walsh, M. C., and Li, X. C. 2012. OX40 signaling favors the induction of TH9 cells and airway inflammation. Nat. Immunol. 13:981-990. Logan, M. R., Jordan-Williams, K. L., Poston, S., Liao, S., and Taparowsky, E. J. 2012. Overexpression of Batf induces an apoptotic defect and an associated lymphoproliferative disorder in mice. Cell Death Dis. e310. doi: 10.1038/cddis.2012.49. Liao, J., Humphrey, S. E., Poston, S., Taparowsky, E. J. 2011. Batf promotes growth arrest and terminal differentiation of mouse myeloid leukemia cells. Mol Cancer Res. 9: 350-362. Betz, B. C., Jordan-Williams, K. L., Wang, C., Kang, S. G., Liao, J., Logan, M. R., Kim, C. H., Taparowsky, B. J. 2010. Batf coordinates multiple aspects of B and T cell function required for a normal antibody response. J Exp Med. 207: 933-942. Zullo, A. J., Benlagha, K., Bendelac, A., Taparowsky, E. J. 2007. Sensitivity of NK1.1-negative NKT cells to transgenic BATF defines a role for activator protein-1 in the expansion and maturation of immature NKT cells in the thymus. J Immunol. 178: 58-66. view article Burton, R. A., Mattila, S., Taparowsky, E. J., Post, C. B. 2006. B-myc: N-terminal recognition of myc binding proteins. Biochemistry. 45: 9857-9865. Deppmann, C. D., Alvania, R. S., Taparowsky, E. J. 2006. Cross-species Annotation of Basic Leucine Zipper Factor Interactions: Insight Into the Evolution of Closed Interaction Networks. Mol Biol Evol. 23: 1480-1492. Liu, H., Deng, X., Shyu, Y. J., Li, J. J., Taparowsky, E. J., Hu, C. D. 2006. Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization. Embo J. 25: 1058-1069. Thornton, T. M., Zullo, A. J., Williams, K. L., Taparowsky, E. J. 2006. Direct manipulation of activator protein-1 controls thymocyte proliferation in vitro. Eur J Immunol. 36: 160-169. Tuveson, D. A., Zhu, L., Gopinathan, A., Willis, N. A., Kachatrian, L., Grochow, R., Pin, C. L., Mitin, N. Y., Taparowsky, E. J., Gimotty, P. A., Hruban, R. H., Jacks, T., Konieczny, S. F. 2006. Mist1-KrasG12D knock-in mice develop mixed differentiation metastatic exocrine pancreatic carcinoma and hepatocellular carcinoma. Cancer Res. 66: 242-247. Vinson, C., Acharya, A., Taparowsky, E. J. 2006. Deciphering B-ZIP transcription factor interactions in vitro and in vivo. Biochim Biophys Acta. 1759: 4-12. Zullo, A. J., Brutkiewicz, R. R., Taparowsky, E. J. 2006. Selective identification of Vα14i T cells using slide-immobilized, CD1d-antigen complexes. J Immunoassay Immunochem. 27: 207-212. Mitin, N., Konieczny, S. F., Taparowsky, E. J. 2005. RAS and the RAIN/RasIP1 Effector. Methods Enzymol. 407: 322-335. Deppmann, C. D., Acharya, A., Rishi, V., Wobbes, B., Smeekens, S., Taparowsky, E. J., Vinson, C. 2004. Dimerization specificity of all 67 B-ZIP motifs in Arabidopsis thaliana: a comparison to Homo sapiens B-ZIP motifs. Nucleic Acids Res. 32: 3435-3445. Mitin, N. Y., Ramocki, M. B., Zullo, A. J., Der, C. J., Konieczny, S. F., Taparowsky, E. J. 2004. Identification and characterization of rain, a novel Ras-interacting protein with a unique subcellular localization. J Biol Chem. 279: 22353-22361. Deppmann, C. D., Taparowsky, E. J. 2003. Reverse-polarity PAGE for examining DNA binding domain phosphorylation. Biotechniques. 34: 56-59. Deppmann, C. D., Thornton, T. M., Utama, F. E., Taparowsky, E. J. 2003. Phosphorylation of BATF regulates DNA binding: a novel mechanism for AP-1 (activator protein-1) regulation. Biochem J. 374: 423-431. Johansen, L. M., Deppmann, C. D., Erickson, K. D., Coffin, W. F., 3rd, Thornton, T. M., Humphrey, S. E., Martin, J. M., Taparowsky, E. J. 2003. EBNA2 and activated Notch induce expression of BATF. J Virol. 77: 6029-6040. Williams, K. L., Zullo, A. J., Kaplan, M. H., Brutkiewicz, R. R., Deppmann, C. D., Vinson, C., Taparowsky, E. J. 2003. BATF transgenic mice reveal a role for activator protein-1 in NKT cell development. J Immunol. 170: 2417-2426.

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