个人简介
EDUCATION
2005 Diplomate of the American Board of Medical Genetics (August 2005) - Clinical Molecular Genetics Specialty. Yale University School of Medicine, Department of Genetics - Medical Genetics Training Program (2002-2005)
2002-2005 Postdoctoral Training, Yale University School of Medicine, Department of Genetics (Supervisor: Kenneth K. Kidd)
1999-2002 National University of Athens, PhD
1999-2000 University of Oxford, “Wellcome Trust Centre for Human Genetics” – Training Fellowship
POSITIONS
2015 Associate Professor of Population Genetics, (tenured) Democritus University of Thrace, Department of Molecular Biology and Genetics
2010-2015 Assistant Professor of Population Genetics, Democritus University of Thrace, Department of Molecular Biology and Genetics
2011 Adjunct Investigator, National Institute of Child Health and Human Development, Bethesda, USA
2005-2010 Lecturer in Population Genetics, Democritus University of Thrace, Department of Molecular Biology and Genetics
2007 Visiting Scientist, Center for Neurobehavioral Genetics, Medical School, University of California Los Angeles, USA
2006 Visiting Specialist, Institute for Human Genetics, University of California San Francisco, USA
2002-2005 Postdoctoral Fellow, Department of Genetics, Yale University School of Medicine, USA
1999-2002 Research Associate, National University of Athens - European Cooperation Project: “Diabetes Prediction and Prevention - DIPP DEMO Project”
Boards of scientific societies
2014-2017 Board Member European Society for the Study of Tourette Syndrome (ESSTS)
2011-2014 Chair of the European Society for the Study of Tourette Syndrome (ESSTS)
2011-2012 Treasurer of the Board of Directors - Hellenic Association for Medical Genetics
Editorial boards
2009-today Academic Editor - Journal of Medical Genetics
2011-today Review Editor - Frontiers in Evolutionary and Population Genetics
2012-today Academic Editor - PLOS ONE
2015 Editor – Frontiers Research Topic: The Neurobiology and Genetics of Gilles de la Tourette Syndrome
近期论文
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Le Guennec K, Quenez O, Nicolas G, Wallon D, Rousseau S, Richard AC, Alexander J, Paschou P, Charbonnier C, Bellenguez C, Grenier-Boley B, Lechner D, Bihoreau MT, Olaso R, Boland A, Meyer V, Deleuze JF, Amouyel P, Munter HM, Bourque G, Lathrop M, Frebourg T, Redon R, Letenneur L, Dartigues JF, Martinaud O, Kalev O, Mehrabian S, Traykov L, Str?bel T, Le Ber I, Caroppo P, Epelbaum S, Jonveaux T, Pasquier F, Rollin-Sillaire A, Génin E, Guyant-Maréchal L, Kovacs GG, Lambert JC, Hannequin D, Campion D, Rovelet-Lecrux A (2016). 17q21.31 duplication causes prominent tau-related dementia with increased MAPT expression. Mol Psychiatry, in press.
Alexander J, Kalev O, Mehrabian S, Traykov T, Raycheva M, Kanakis D, Drineas P, Lutz MI, Str?bel T, Penz T, Schuster M, Bock C, Ferrer I, Paschou P, Kovacs G (2016). Familial early-onset dementia with complex neuropathological phenotype and genomic background. Neurobiology of Aging, 42:199-204.
Tsetsos F, Padmanabhuni SS, Alexander J, Karagiannidis I, Tsifintaris M, Topaloudi A, Mantzaris D, Georgitsi M, Drineas P, Paschou P (2016). Meta-Analysis of Tourette Syndrome and Attention Deficit Hyperactivity Disorder GWAS Provides Support for a Shared Genetic Basis. Front Neurosci 10:340.
Zilh?o NR, Padmanabhuni SS, Pagliaroli L, Barta C; BIOS Consortium, Smit DJ, Cath D, Nivard MG, Baselmans BM, van Dongen J, Paschou P, Boomsma DI (2015). Epigenome-Wide Association Study of Tic Disorders.Twin Res Hum Genet, 18(6):699-709.
Paschou P, Drineas P, Yannaki E, Razou A, Kanaki K, Tsetsos F , Padmanabhuni SS, Michalodimitrakis M, Renda MC, Pavlovic S, Anagnostopoulos A, Stamatoyannopoulos JA, Kidd KK, Stamatoyannopoulos G (2014). A maritime route of colonization of Europe. Proceedings of the National Academy of Sciences USA, 111:9211-9216.
Paschou P, Yu, D, Gerber G, Evans P, Tsetsos F, Davis LK, Karagiannidis I et al. Genetic association signal near NTN4 in Tourette Syndrome (2014). Annals of Neurology, 76:310-315.
Karagiannidis I, Dehning S, Sandor P, Tarnok Z, Rizzo R, Wolanczyk T, Madruga-Garrido M, Hebebrand J, N?then MM, Lehmkuhl G, Farkas L, Nagy P, Szymanska U, Anastasiou Z, Stathias V, Androutsos C, Tsironi V, Koumoula A, Barta C, Zill P, Mir P, Müller N, Barr C, Paschou P (2013). Support of the histaminergic hypothesis in Tourette syndrome: association of the histamine decarboxylase gene in a large sample of families. J Med Genet 50(11):760-764.
Hughey JR, Paschou P, Drineas P, Mastropaolo D, Lotakis DM, Navas PA, Michalodimitrakis M, Stamatoyannopoulos JA, Stamatoyannopoulos G (2013). A European Population in the Minoan Bronze Age Crete. Nature Communications, 4: 1861.
Donnelly MP, Paschou P, Grigorenko E, Gurwitz D, Barta C, Lu RB, Zhukova OV, Kim JJ, Siniscalco M, New M, Li H, Kajuna S, Manolopoulos VG, Speed WC, Pakstis AJ, Kidd JR, Kidd KK (2012). A global view of the OCA2-HERC2 region and pigmentation. Human Genetics 131(5): (683-696).
Karagiannidis I, Rizzo R, Tarnok Z, Wolanczyk T, Hebebrand J, Noethen MM, Lehmkuhl G, Farkas L, Nagy P, Barta C, Szymanska U, Panteloglou G, Miranda DM, Feng Y, Sandor P, Barr C, Paschou P. The most common worldwide haplotype across SLITRK1 is associated with Tourette Syndrome in a large sample of families (2011). Molecular Psychiatry 17(7): 665-668 .
Donnelly MP, Paschou P, Grigorenko E, Gurwitz D, Mehdi SQ, Kajuna SL, Barta C, Kungulilo S, Karoma NJ, Lu RB, Zhukova OV, Kim JJ, Comas D, Siniscalco M, New M, Li P, Li H, Manolopoulos VG, Speed WC, Rajeevan H, Pakstis AJ, Kidd JR, Kidd KK (2010). The distribution and most recent common ancestor of the 17q21 inversion in humans. Am J Hum Genet 86, 161-171.
Paschou P, Lewis J, Javed A, Drineas P (2010). Ancestry informative markers for fine-scale individual assignment to worldwide populations. Journal of Medical Genetics 47, 835-847.
Paschou P, Drineas P, Lewis J, Nievergelt CM, Nickerson DA, Smith JD, Ridker PM, Chasman DI, Krauss RM, Ziv E (2008). Tracing sub-structure in the European American population with PCA-informative markers. PLoS Genetics 4:e1000114.
Paschou P, Mahoney M, Pakstis A, Kidd JR, Kidd KK, Drineas P (2007). Inter- and intrapopulation genotype reconstruction from tagging SNPs. Genome Research 17, 96-107.
Paschou P, Ziv E, Burchard EG, ChoudryS, Rodriguez-Cintron W, Mahoney MW, Drineas P (2007). PCA-correlated SNPs for structure identification in worldwide human populations. PLoS Genetics 3, e160.
Paschou P, Feng Y, Pakstis AJ, Speed WC, DeMille MM, Kidd JR, Jaghori B, Kurlan R, Pauls DL, Sandor P, Barr CL, Kidd KK (2004). Indications of linkage and association of Gilles de la Tourette syndrome in two independent family samples: 17q25 is a putative susceptibility region. Am J Hum Genet 75,545-560.