Belkin, Alexey M. - University of Maryland-Baltimore - Department of Biochemistry and Molecular Biology

研究领域

Cell-matrix interactions, cell migration, integrins, transglutaminases

近期论文

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Akimov S.S., D. Krylov, L.F. Fleischman, and A.M. Belkin. (2000). Tissue transglutaminase is an integrin-binding adhesion coreceptor for fibronectin. J. Cell Biol., 148:825-838. Belkin, A.M., and M.A. Stepp. (2000). Integrins as receptors for laminins. Microsc. Res. Tech., 51:280-301. Belkin, A.M., S.S. Akimov, L.S. Zaritskaya, B.I. Ratnikov, E.I. Deryugina, and A.Y. Strongin. (2001). Matrix-dependent proteolysis of surface transglutaminase by membrane-type metalloproteinase regulates cancer cell adhesion and locomotion. J. Biol. Chem., 276:18415-18422. Akimov, S.S., and A.M. Belkin. (2001). Cell surface transglutaminase promote fibronectin assembly via interaction with the gelatin-binding domain of fibronectin: a role in TGFb-dependent matrix deposition. J. Cell Sci., 114:2989-3000. Akimov, S.S., and A.M. Belkin. (2001). Cell surface tissue transglutaminase is involved in adhesion and migration of monocytic cells on fibronectin. Blood, 98:1567-1576. Akimov, S.S., and A.M. Belkin. (2003). Opposing roles of H-Ras/Raf-1 oncogenes and the MEK1/ERK signaling module in regulation of expression and adhesive function of surface transglutaminase. J. Biol. Chem., 278:35609-35619. Belkin, A.M., E.A. Zemskov, J. Hang, S.S. Akimov, S. Sikora, and A.Y. Strongin. (2004). Cell-surface-associated tissue transglutaminase is a target of MMP-2 proteolysis. Biochemistry, 43:11760-11769. Belkin A.M, G. Tsurupa, E. Zemskov, Y. Veklich, J.W. Weisel, and L. Medved. (2005). Transglutaminase-mediated oligomerization of the fibrin(ogen) alphaC-domains promotes integrin-dependent cell adhesion and signaling. Blood, 105:3561-3568. Hang, J., E. Zemskov, L Lorand, and A.M. Belkin. (2005). Identification of a novel recognition sequence for fibronectin within the NH2-terminal beta-sandwich domain of tissue transglutaminase. J. Biol. Chem., 280:23675-23683. Zemskov, E., A. Janiak, J. Hang, A. Waghray, and A.M. Belkin. (2006). The role of tissue transglutaminase in cell-matrix interactions. Frontiers in Bioscience, 11:1057-1076.