Leung, Yuk Fai - Purdue University - Department of Biological Sciences

个人简介

Ph.D., Chinese University of Hong Kong, Hong Kong, 2002 M.Phil., Hong Kong University of Science and Technology, Hong Kong, 1998 B.Sc., Hong Kong University of Science and Technology, Hong Kong 1996

近期论文

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Zhang YQ, Bonilla S, Chong L, Leung YF. Irx7, a Smarca4-regulated gene for retinal differentiation, regulates other genes controlled by Smarca4 in zebrafish retinas. Gene Expr Patterns. 2013 Jun-Jul;13:177-82. Zhang LY, Cho J, Ptak D, Leung YF. The role of egr1 in early zebrafish retinogenesis. PLOS ONE. 2013; 8:e56108. Li Z, Zhang LY, Leung YF. Use of the zebrafish model to study refractive errors. Expert Rev Ophthalmol. 2013; 8:1-3. Zhang LY, Chong L, Cho J, Liao PC, Shen F, Leung YF. Drug Screening to Treat Early-Onset Eye Diseases: Can Zebrafish Expedite the Discovery? Asia-Pac J Ophthalmol 2012; 1:374-383. Zhang Y, Yang Y, Trujillo C, Zhong W, Leung YF. The expression of irx7 in the inner nuclear layer of zebrafish retina is essential for a proper retinal development and lamination. PLoS One. 2012;7(4):e36145. Li Z, Ptak D, Zhang L, Walls EK, Zhong W, Leung YF. Phenylthiourea specifically reduces zebrafish eye size. PLoS One. 2012;7(6):e40132. Hensley MR, Hessenplug E, McPhail R, Leung YF. ZeBase: An open-source relational database for zebrafish laboratories. Zebrafish. 2012 Mar;9(1):44-9. Hensley, M. R., Emran, F., Bonilla, S., Zhang, L., Zhong, W., Grosu, P., Dowling, J. E., Leung, Y. F. 2011. Cellular expression of Smarca4 (Brg1)-regulated genes in zebrafish retinas. BMC Develomental Biology. 45: 11. Pubmed PMID:21756345; PubMed Central PMCID: PMC3155967. Hensley, MR, Leung, YF. 2010. A Convenient Dry Feed for Raising Zebrafish Larvae. Zebrafish. 7: 219-231. Zhang, L, Leung, YF. 2010. Microdissection of Zebrafish Embryonic Eye Tissues. J. Vis. Exp. 40: pii: 2028. Leung YF, Ma P, Link BA, Dowling JE. 2008. Factorial microarray analysis of zebrafish retinal development. Proc Natl Acad Sci U S A. 105(35): 12909-14. Leung, Y. F., Ma, P., Dowling, J. E. 2007. Gene expression profiling of zebrafish embryonic retinal pigment epithelium in vivo. Invest Ophthalmol Vis Sci. 48: 881-890. Leung, Y. F., Dowling, J. E. 2005. Gene expression profiling of zebrafish embryonic retina. Zebrafish. 2: 269-283. Fan, B. J., Leung, Y. F., Pang, C. P., Baum, L., Tam, O. S., Wang, N., Lam, S. C. 2004. Single nucleotide polymorphisms of the myocilin gene in primary open-angle glaucoma patients. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 21: 70-73. Fan, B. J., Leung, Y. F., Pang, C. P., Fan, D. S., Wang, D. Y., Tong, W. C., Tam, P. O., Chua, J. K., Lau, T. C., Lam, D. S. 2004. Polymorphisms in the myocilin promoter unrelated to the risk and severity of primary open-angle glaucoma. J Glaucoma. 13: 377-384. Fan, B. J., Leung, Y. F., Wang, N., Lam, S. C., Liu, Y., Tam, O. S., Pang, C. P. 2004. Genetic and environmental risk factors for primary open-angle glaucoma. Chin Med J (Engl). 117: 706-710. Lam, D. S., Lee, W. S., Leung, Y. F., Tam, P. O., Fan, D. S., Fan, B. J., Pang, C. P. 2003. TGFbeta-induced factor: a candidate gene for high myopia. Invest Ophthalmol Vis Sci. 44: 1012-1015. Lam, D. S., Tam, P. O., Fan, D. S., Baum, L., Leung, Y. F., Pang, C. P. 2003. Familial high myopia linkage to chromosome 18p. Ophthalmologica. 217: 115-118. Leung, Y. F., Cavalieri, D. 2003. Fundamentals of cDNA microarray data analysis. Trends Genet. 19: 649-659. Leung, Y. F., Fan, B. J., Lam, D. S., Lee, W. S., Tam, P. O., Chua, J. K., Tham, C. C., Lai, J. S., Fan, D. S., Pang, C. P. 2003. Different optineurin mutation pattern in primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 44: 3880-3884. Leung, Y. F., Tam, P. O., Lee, W. S., Lam, D. S., Yam, H. F., Fan, B. J., Tham, C. C., Chua, J. K., Pang, C. P. 2003. The dual role of dexamethasone on anti-inflammation and outflow resistance demonstrated in cultured human trabecular meshwork cells. Mol Vis. 9: 425-439. Leung, Y. F. 2002. Unravelling the mystery of microarray data analysis. Trends Biotechnol. 20: 366-368. Leung, Y. F., Pang, C. P. 2002. EYE on bioinformatics: dissecting complex disease traits in silico. Appl Bioinformatics. 1: 69-80. Pang, C. P., Leung, Y. F., Fan, B., Baum, L., Tong, W. C., Lee, W. S., Chua, J. K., Fan, D. S., Liu, Y., Lam, D. S. 2002. TIGR/MYOC gene sequence alterations in individuals with and without primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 43: 3231-3235. Leung, Y. F., Lam, D. S., Pang, C. P. 2001. When drugs development meets genomics. Pharmacogenomics J. 1: 237-238.