当前位置: X-MOL首页全球导师 海外导师 › Friedman, Alan

个人简介

Ph.D., Yale, 1989

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Avramova, L. V., Desai, J., Weaver, S., Friedman, A. M., Bailey-Kellogg, C. 2008. Robotic hierarchical mixing for the production of combinatorial libraries of proteins and small molecules. J Comb Chem. 10: 63-68. Williamson, T. E., Craig, B. A., Kondrashkina, E., Bailey-Kellogg, C., Friedman, A. M. 2008. Analysis of self-associating proteins by singular value decomposition of solution scattering data. Biophys J. 94: 4906-4923. Ye, X., Friedman, A. M., Bailey-Kellogg, C. 2007. Hypergraph model of multi-residue interactions in proteins: sequentially-constrained partitioning algorithms for optimization of site-directed protein recombination. J Comput Biol. 14: 777-790. Saftalov, L., Smith, P. A., Friedman, A. M., Bailey-Kellogg, C. 2006. Site-directed combinatorial construction of chimaeric genes: general method for optimizing assembly of gene fragments. Proteins. 64: 629-642. Schultz, D. A., Friedman, A. M., White, M. A., Fox, R. O. 2005. The crystal structure of the cis-proline to glycine variant (P114G) of ribonuclease A. Protein Sci. 14: 2862-2870. Pincas, H., Pingle, M. R., Huang, J., Lao, K., Paty, P. B., Friedman, A. M., Barany, F. 2004. High sensitivity EndoV mutation scanning through real-time ligase proofreading. Nucleic Acids Res. 32: e148. Potluri, S., Khan, A. A., Kuzminykh, A., Bujnicki, J. M., Friedman, A. M., Bailey-Kellogg, C. 2004. Geometric analysis of cross-linkability for protein fold discrimination. Pac Symp Biocomput. 447-458. Ye, X., O'Neil, P. K., Foster, A. N., Gajda, M. J., Kosinski, J., Kurowski, M. A., Bujnicki, J. M., Friedman, A. M., Bailey-Kellogg, C. 2004. Probabilistic cross-link analysis and experiment planning for high-throughput elucidation of protein structure. Protein Sci. 13: 3298-3313. Bennett, E. J., Bjerregaard, J., Knapp, J. E., Chavous, D. A., Friedman, A. M., Royer, W. E., Jr., O'Connor, C. M. 2003. Catalytic implications from the Drosophila protein L-isoaspartyl methyltransferase structure and site-directed mutagenesis. Biochemistry. 42: 12844-12853. Ng, P. S., Pingle, M. R., Balasundarum, G., Friedman, A., Zu, X., Bergstrom, D. E. 2003. Endcaps for stabilizing short DNA duplexes. Nucleosides Nucleotides Nucleic Acids. 22: 1635-1637. Zhu, Z., Zhou, J., Friedman, A. M., Xu, S. Y. 2003. Isolation of BsoBI restriction endonuclease variants with altered substrate specificity. J Mol Biol. 330: 359-372. Smith, C. D., Carson, M., Friedman, A. M., Skinner, M. M., Delucas, L., Chantalat, L., Weise, L., Shirasawa, T., Chattopadhyay, D. 2002. Crystal structure of human L-isoaspartyl-O-methyl-transferase with S-adenosyl homocysteine at 1.6-A resolution and modeling of an isoaspartyl-containing peptide at the active site. Protein Sci. 11: 625-635. van der Woerd, M. J., Pelletier, J. J., Xu, S., Friedman, A. M. 2001. Restriction enzyme BsoBI-DNA complex: a tunnel for recognition of degenerate DNA sequences and potential histidine catalysis. Structure. 9: 133-144. Skinner, M. M., Puvathingal, J. M., Walter, R. L., Friedman, A. M. 2000. Crystal structure of protein isoaspartyl methyltransferase: a catalyst for protein repair. Structure. 8: 1189-1201. Walter, R. L., Ealick, S. E., Friedman, A. M., Blake, R. C., 2nd, Proctor, P., Shoham, M. 1996. Multiple wavelength anomalous diffraction (MAD) crystal structure of rusticyanin: a highly oxidizing cupredoxin with extreme acid stability. J Mol Biol. 263: 730-751. Friedman, A. M., Fischmann, T. O., Steitz, T. A. 1995. Crystal structure of lac repressor core tetramer and its implications for DNA looping. Science. 268: 1721-1727. Shamoo, Y., Friedman, A. M., Parsons, M. R., Konigsberg, W. H., Steitz, T. A. 1995. Crystal structure of a replication fork single-stranded DNA binding protein (T4 gp32) complexed to DNA. Nature. 376: 362-366. Paliwal, V., Friedman, A. M., Ptak, W., Askenase, P. W. 1994. Monoclonal, antigen-specific, T cell contrasuppressor factor expresses determinants of TCR alpha-chain (not necessarily TCR beta-chain), having a molecular mass of about 40 kDa. J Immunol. 152: 2811-2820. Ptak, W., Friedman, A. M., Flood, P. M. 1994. Generation of anti-hapten T cell cytotoxicity in vivo. Relationship to contact sensitivity and the role of contrasuppression. Arch Immunol Ther Exp (Warsz). 42: 185-192. Friedman, A. M., Ptak, W., Brewer, E., Green, D. R., Reuter, P. A., Flood, P. M. 1990. Generation of a T-cell hybridoma producing a contrasuppressor factor for contact sensitivity. Immunology. 71: 282-289. Friedman, A. M., Ptak, W., Freedman, J., Green, D. R., Flood, P. M. 1989. Prevention of tumor growth and enhancement of cell-mediated immunity by an antigen-specific contrasuppressor factor from a T cell hybridoma. Prog Clin Biol Res. 288: 281-288. Green, D. R., Friedman, A., Ptak, W., McGhee, J., Flood, P. M. 1989. Contrasuppression, tolerance, and tumor immunity. Prog Clin Biol Res. 288: 245-258. Flood, P. M., Friedman, A., Freedman, J., Horvat, B., Reuter, P., Ptak, W. 1988. The role of contrasuppression in tumor regression. Immunol Res. 7: 12-22. Ptak, W., Friedman, A., Bereta, M., Marcinkiewicz, J., Horvat, B., Reuter, P., Green, D. R., Flood, P. M. 1988. The role of contrasuppressor T cells in the adoptive transfer of contact sensitivity responses to picryl chloride. Immunol Res. 7: 1-11. Flood, P. M., Friedman, A., Horvat, B., Reuter, P., Rodriquez, A., Ptak, W. 1987. Contrasuppression and tumor rejection. Immunol Lett. 16: 297-303.

推荐链接
down
wechat
bug