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Ph.D., University of California - Berkeley, 1995.

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Kandachar, V., T. Bai, and H. C. Chang. 2008. The clathrin-binding motif and the J-domain of Drosophila auxilin are essential for facilitating Notch ligand endocytosis. BMC Dev Biol. 8: 50. Hagedorn, E. J., Bayraktar, J. L., Kandachar, V. R., Bai, T., Englert, D. M., Chang, H. C. 2006. Drosophila melanogaster auxilin regulates the internalization of Delta to control activity of the Notch signaling pathway. J Cell Biol. 173: 443-452. Delamarre, L., Pack, M., Chang, H., Mellman, I., Trombetta, E. S. 2005. Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate. Science. 307: 1630-1634. Chang, H. C., Hull, M., Mellman, I. 2004. The J-domain protein Rme-8 interacts with Hsc70 to control clathrin-dependent endocytosis in Drosophila. J Cell Biol. 164: 1055-1064. Chang, H. C., Newmyer, S. L., Hull, M. J., Ebersold, M., Schmid, S. L., Mellman, I. 2002. Hsc70 is required for endocytosis and clathrin function in Drosophila. J Cell Biol. 159: 477-487. Chang, H. C., Rubin, G. M. 1997. 14-3-3 epsilon positively regulates Ras-mediated signaling in Drosophila. Genes Dev. 11: 1132-1139. Rubin, G. M., Chang, H. C., Karim, F., Laverty, T., Michaud, N. R., Morrison, D. K., Rebay, I., Tang, A., Therrien, M., Wassarman, D. A. 1997. Signal transduction downstream from Ras in Drosophila. Cold Spring Harb Symp Quant Biol. 62: 347-352. Allard, J. D., Chang, H. C., Herbst, R., McNeill, H., Simon, M. A. 1996. The SH2-containing tyrosine phosphatase corkscrew is required during signaling by sevenless, Ras1 and Raf. Development. 122: 1137-1146. Karim, F. D., Chang, H. C., Therrien, M., Wassarman, D. A., Laverty, T., Rubin, G. M. 1996. A screen for genes that function downstream of Ras1 during Drosophila eye development. Genetics. 143: 315-329. Wassarman, D. A., Solomon, N. M., Chang, H. C., Karim, F. D., Therrien, M., Rubin, G. M. 1996. Protein phosphatase 2A positively and negatively regulates Ras1-mediated photoreceptor development in Drosophila. Genes Dev. 10: 272-278. Chang, H. C., Solomon, N. M., Wassarman, D. A., Karim, F. D., Therrien, M., Rubin, G. M., Wolff, T. 1995. Phyllopod functions in the fate determination of a subset of photoreceptors in Drosophila. Cell. 80: 463-472. Therrien, M., Chang, H. C., Solomon, N. M., Karim, F. D., Wassarman, D. A., Rubin, G. M. 1995. KSR, a novel protein kinase required for RAS signal transduction. Cell. 83: 879-888. Chang, H. C., Karim, F. D., O'Neill, E. M., Rebay, I., Solomon, N. M., Therrien, M., Wassarman, D. A., Wolff, T., Rubin, G. M. 1994. Ras signal transduction pathway in Drosophila eye development. Cold Spring Harb Symp Quant Biol. 59: 147-153. Gaul, U., Chang, H., Choi, T., Karim, F., Rubin, G. M. 1993. Identification of ras targets using a genetic approach. Ciba Found Symp. 176: 85-92 discussion 92-85.

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