个人简介

Post-Doctoral Iowa State University 1988; Ph.D. Northeastern University 1987; B.S. Charter Oak College 1982

研究领域

Analytical Forensic/Toxicological Sensors and Imaging

Dr. LaCourse’s research interests include basic and applied research on hydrodynamic electroanalytical techniques in liquid chromatography and capillary electrophoresis, adsorption phenomena at noble metal electrodes, and advanced sample preparation techniques (e.g., microdialysis and pressurized-fluid extraction). A major thrust of his efforts is to further understand and expand the limits of pulsed electrochemical detection (PED) techniques for the determination of polar aliphatic compounds. Dr. LaCourse applies PED to (bio)analytical problems of critical significance in the areas of pharmaceutical, toxicological, forensic, environmental, pharmaceutical, and life science arenas.

近期论文

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Lu, Hua; Salimian, Sasan; Gamelin, Emily; Wang, Guoying; Fedorowski, Jennifer; LaCourse, William; Greenberg, Jean, Genetic analysis of acd6-1 reveals complex defense networks and leads to identification of novel defense genes in Arabidopsis, The Plant Journal, 2008, submitted for publication. S. Ge, H. Lam, S.J. Modi, W.R. LaCourse, G. Rao, and L. Tolosa, Comparing the Performance of the Optical Glucose Assay Based on Glucose Binding Protein with HPAEC-PED: Efforts to Design a Low-Cost-Point-of-Care Glucose Sensor. J. of Diabetes Science and Tech., 2007, 1(6), 864-872. An improved method to detect ethyl glucuronide in urine using reversed-phase liquid chromatography and pulsed electrochemical detection, R. Kaushik, and W.R. LaCourse, Anal. Chim. Acta, 2007, 576(2), 239-245. Determination of ethyl glucuronide in urine using reversed-phase HPLC and pulsed electrochemical detection (Part II), Kaushik, R.; LaCourse, W. R.; Levine, B. Anal. Chim. Acta, 2006, 556(2), 267-274. A brief review: HPLC methods to directly detect drug glucuronides in biological matrices (Part I). Kaushik, R.; Levine, B.; LaCourse, W. R. Anal. Chim. Acta, 2006, 556(2), 255-266. Application of Photoassisted Electrochemical Detection to Explosive-Containing Environmental Samples. Marple, R. L.; LaCourse, W.R. Anal. Chem., 2005, 77(20), 6709-6714. Microelectrode applications of pulsed electrochemical detection. LaCourse, W. R.; Modi, S. J. Electroanalysis, 2005, 17(13), 1141-1152. A platform for on-site environmental analysis of explosives using high performance liquid chromatography with UV absorbance and photo-assisted electrochemical detection. Marple, R. L.; LaCourse, W. R. Talanta, 2005, 66(3), 581-590.