Lippard, Stephen J. - Massachusetts Institute of Technology

研究领域

Biological/Inorganic/Environmental

近期论文

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Oxidative halogenation of cisplatin and carboplatin: Synthesis, spectroscopy, and crystal and molecular structures of Pt(iv) prodrugs. Timothy C. Johnstone, Sarah M. Alexander, Justin J. Wilson, and Stephen J. Lippard, Dalton Trans., 44, 119-129 (2015). Peptide targeting of fluorescein-based sensors to discrete intracellular locales. Robert J. Radford, Wen Chyan and Stephen J. Lippard , Chem. Sci., 5, 4512-4516 (2014). Synthesis of bis(imidazole) metal complexes and their use in rapid NO detection and quantification devices. Eric Victor, Sunghee Kim, and Stephen J. Lippard, Inorg. Chem., 53, 12809-12821 (2014). Component interactions and electron transfer in toluene/o-xylene monooxygenase. Alexandria D. Liang and Stephen J. Lippard, Biochemistry, 53, 7368-7375 (2014). Peptide targeting of fluorescein-based sensors to discrete intracellular locales. Robert J. Radford, Wen Chyan, and Stephen J. Lippard , Chem. Sci., 5, 4512-4516 (2014). A breast cancer stem cell-selective, mammospheres-potent osmium(VI) nitrido complex. Kogularamanan Suntharalingam, Wei Lin, Timothy C. Johnstone, Peter M. Bruno, Yao-Rong Zheng, Michael T. Hemann, and Stephen J. Lippard, J. Am. Chem. Soc., 136, 14413-14416 (2014). Light-induced N2O production from a non-heme iron-nitrosyl dimer. Yunbo Jiang, Takahiro Hayashi, Hirotoshi Matsumura, Loi H. Do, Amit Majumdar, Stephen J. Lippard, and Pierre Mo?nne-Loccoz, J. Am. Chem. Soc., 136, 12524-12527 (2014). Improvements in the synthesis and understanding of the iodo-bridged intermediate en route to the Pt(IV) prodrug satraplatin. Timothy C. Johnstone and Stephen J. Lippard, Inorg. Chim. Acta., 424, 254-259 (2014). Synthesis and characterization of a linear dinitrosyl-triiron complex. Eric Victor, Mikael A. Minier, and Stephen J. Lippard, Eur. J. Inorg. Chem., 33, 5640-5645 (2014). Electron transfer control in soluble methane monooxygenase. Weixue Wang, Roxana E. Iacob, Rebecca P. Luoh, John R. Engen, and Stephen J. Lippard, J. Am. Chem. Soc., 136, 9754-9762 (2014). Addition of a second binding site increases the dynamic range but alters the cellular localization of a red fluorescent probe for mobile zinc. Andrei Loas, Robert J. Radford , and Stephen J. Lippard, Inorg. Chem., 53, 6491-9493 (2014). Structural and mechanistic studies of polymerase η bypass of phenanthriplatin DNA damage. Mark T. Gregorya, Ga Young Park, Timothy C. Johnstone, Young-Sam Lee, Wei Yang, and Stephen J. Lippard, Proc. Natl. Acad. Sci. USA, 111, 9133-9138 (2014). Pt(IV) prodrugs designed to bind non-covalently to human serum albumin for drug delivery. Yao-Rong Zheng, Kogularamanan Suntharalingam, Timothy C. Johnstone, Hyunsuk Yoo, Wei Lin, Jamar G. Brooks, and Stephen J. Lippard, J. Am. Chem. Soc., 136, 8790-8798 (2014). A flexible glutamine regulates the catalytic activity of toluene o -xylene monooxygenase. Alexandria D. Liang, Alexandra T. Wrobel, and Stephen J. Lippard, Biochemistry, 53, 3585-3592 (2014). A tetranitrosyl [4Fe-4S] cluster forms en route to roussins black anion: Nitric oxide reactivity of [Fe4S4(LS3)L] 2-. Eric Victor and Stephen J. Lippard, Inorg. Chem., 53, 5311-5320 (2014). Two-photon imaging of Zn2+ dynamics in mossy fiber boutons of adult hippocampal slices. Mustafa Khana, Christian R. Goldsmith, Zhen Huang, John Georgiou, Thomas T. Luybena, John C. Rodera, Stephen J. Lippard, and Kenichi Okamotoa, Proc. Natl. Acad. Sci. USA, 111, 6786-6791 (2014). Synthetic methods for the preparation of platinum anticancer complexes. Justin J. Wilson and Stephen J. Lippard, Chem. Rev., 114, 4470-4495 (2014). A fast and selective near-infrared fluorescent sensor for multicolor imaging of biological nitroxyl (HNO). Alexandra T. Wrobel, Timothy C. Johnstone, Alexandria D. Liang, Stephen J. Lippard , and Pablo Rivera-Fuentes, J. Am. Chem. Soc., 136, 4697-4705 (2014). Conversion between doubly and triply carboxylate bridged Bis(ethylzinc) Complexes and Formation of the (μ-Oxo)tetrazinc Carboxylate [Zn 4O(ArTolCO2)6]. Mikael A. Minier and Stephen J. Lippard, Organometallics, 33, 1462-1466 (2014). Conjugation of vitamin e analog α-TOS to Pt(iv) complexes for dual-targeting anticancer therapy. Kogularamanan Suntharalingam, Ying Song, and Stephen J. Lippard, Chem. Comm., 50, 2465-2468 (2014).