个人简介

Post-Doctoral Oak Ridge National Laboratory 1999; Ph.D. University of South Carolina 1998; B.S. Frostburg State University 1994

研究领域

Analytical Sensors and Imaging Spectroscopy/Dynamics

Bioanalytical and Environmental Spectroscopy Research in our group involves the development of novel sensing tools and strategies for the monitoring of biological and environmental systems at both the nano- and macro-scales. On the nano-scale, we are developing implantable sensors capable of being inserted into individual cells and optically positioned for the monitoring of cellular response to various external stimuli. On the macro-scale, we are developing new spectroscopic techniques for real-time disease (i.e., cancer) diagnosis in clinical and surgical settings.

近期论文

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B. M. Cullum, “Sample Collection and Preparation of Liquids and Solids,” in Handbook of Spectroscopy; Gunter Gauglitz and Tuan Vo-Dinh (eds.), Weinheim, Germany, Wiley-VCH Verlag GmbH & Co., 2nd edition, 2011, in press. T. Vo-Dinh and B. M. Cullum, “Fluorescence Spectroscopy for Biomedical Diagnostics,” in CRC Handbook of Biomedical Photonics; Tuan Vo-Dinh (ed.), Boca Raton, CRC Press, 2nd edition, 2011, in press. C. K. Klutse, T. Vo-Dinh and B. M. Cullum , “Nanosensors for Single-Cell Analyses,” in CRC Handbook of Biomedical Photonics; Tuan Vo-Dinh (ed.), Boca Raton, CRC Press, 2nd edition, 2011, in press. C. K. Klutse, and B. M. Cullum, “Development of SAM-based Multi-layer SERS Substrates for Intracellular Analyses”, Proc. SPIE – Soc. Opt. Eng., 7674, p. 767402-1 – 767402-12 (2010). J. B. Kiser and B. M. Cullum, Optical Cross-talk and Surface Characterization of SERS Nanoimaging Bundle Substrates:, Proc. SPIE – Soc. Opt. Eng., 7674, p. 76740D-1 – 76740D-7 (2010). B. M. Cullum, “Sub-Diffraction Limited Raman Chemical Imaging,” in Applications of Surface-Enhanced Raman Spectroscopy; Stuart Farquharson (ed.), New York, CRC Press, in press 2009. C. K. Klutse, H. Li and B. M. Cullum, “Optimization of Multilayer Surface-enhanced Raman Scattering (SERS) Immuno-nanosensors via Self-assembled Monolayer Spacers,” Proc. SPIE – Soc. Opt. Eng., 7313, p. 73130C1 – 73130C10 (2009). J. B. Kiser, M. E. Hankus and B. M. Cullum, “Tunable Fiber Optic Imaging Bundle SERS Substrates,” Proc. SPIE – Soc. Opt. Eng., 7313, p. 73130E1 – 73130E8 (2009). J. Sun, M. E. Hankus and B. M. Cullum, “SERS-based Immuno-microwell Arrays for Multiplexed Detection of Food-borne Pathogenic Bacteria,” Proc. SPIE – Soc. Opt. Eng., 7313, p. 73130K1- 73130K10 (2009). B. M. Cullum*, H. Li, M. V. Schiza and M. E. Hankus, “Characterization of Multi-Layer Enhanced SERS Substrates and Their Potential for SERS Nano-Imaging,” Nanobiotechnol., 3 (1), p. 1 – 11, (2007). H. Li, C. E. Baum, J. Sun and B. M. Cullum, “Multilayer Enhanced Gold Film Over Nanostructure (GFON) Surface-Enhanced Raman Substrates,” Appl. Spectrosc. 60 (12), p. 1377 – 1386, (2006). M. E. Hankus, G. J. Gibson and B. M. Cullum, “Surface Enhanced Raman Scattering (SERS)-based Nanoprobe for High Resolution, Non-scanning Chemical Imaging,” Anal. Chem. 78 (21), p. 7535 – 7546, (2006). H. Li, C. E. Baum and B. M. Cullum, “Characterization of Novel Gold SERS Substrates with Multilayer Enhancements,” SPIE Proceedings, 6380, p. 63800D1 – 63800D12 (2006). M. E. Hankus and B. M. Cullum, “SERS Probes for Imaging Individual Biochemical Species on the Nanoscale,” SPIE Proceedings, 6380, p. 638004/1 – 638004/12 (2006). H. Li, J. Sun and B. M. Cullum, “Label-Free Detection of Proteins Using SERS-Based Immuno-Nanosensors,”Nanobiotechnol., 2 (1-2), p. 17 – 28 (2006). H. Li, C. E. Baum, J. Sun and B. M. Cullum, “Multilayer Enhanced SERS Active Materials: Fabrication, Characterization, and Application to Trace Chemical Detection,” SPIE Proceedings , 6218, p. 22-33, (2006). H. Li and B. M. Cullum, “Dual Layer and Multilayer Enhancements from Silver Film over Nanostructured Surface-Enhanced Raman Substrates,” Appl. Spectrosc. 59 (4), p. 410 – 417, (2005). J. B. Kiser, N. Chandrasekharan and B. M. Cullum, “Sub-surface Brain Tumor Diagnosis Using a Portable NMPPAS-based Fiber Optic Microprobe,” SPIE Proceedings, 6007, p.133-142, (2005). H. Li., C. E. Baum, J. Sun and B. M. Cullum, “Label-free Detection of Antigens using Implantable SERS Nanosensors,” SPIE Proceedings, 6007, p. 58-70, (2005). M. E. Hankus, G. J. Gibson and B. M. Cullum, “Characterization and Optimization of Novel Surface-Enhanced Raman Scattering (SERS)-based Nanoimaging Probes for Chemical Imaging,” SPIE Proceedings,6007, p. 9 – 20, (2005).