Orgel, Joseph - Illinois Institute of Technology

个人简介

B.Sc. (Hons) University of Stirling Ph.D. University of Stirling

近期论文

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2016 Varma S, Orgel JP, Schieber JD. Nanomechanics of Type I Collagen. Biophysical journal. 111(1):50-6. PMID: 27410733, PMCID: PMC4945622 2016 Dutov P, Antipova O, Varma S, Orgel JP, Schieber JD. Measurement of Elastic Modulus of Collagen Type I Single Fiber. PloS one. 11(1):e0145711. PMID: 26800120, PMCID: PMC4723153 2015 Varma S, Botlani M, Hammond JR, Scott HL, Orgel JP, Schieber JD. Effect of intrinsic and extrinsic factors on the simulated D-band length of type I collagen. Proteins. 2015; 83(10):1800-12. PMID: 26214145 2015 Kim T, Sridharan I, Zhu B, Orgel J, Wang R. Effect of CNT on collagen fiber structure, stiffness assembly kinetics and stem cell differentiation. Materials science & engineering. C, Materials for biological applications. 49:281-9. PMID: 25686951 2014 Barrea RA, Antipova O, Gore D, Heurich R, Vukonich M, Kujala NG, Irving TC, Orgel JP. X-ray micro-diffraction studies on biological samples at the BioCAT Beamline 18-ID at the Advanced Photon Source. Journal of synchrotron radiation. 21(Pt 5):1200-5. PMID: 25178013, PMCID: PMC4151685 2014 Zeltz C, Orgel J, Gullberg D. Molecular composition and function of integrin-based collagen glues-introducing COLINBRIs. Biochimica et biophysica acta. 1840(8):2533-48. PMID: 24361615 2014 Orgel JP, Persikov AV, Antipova O. Variation in the helical structure of native collagen. PloS one. 9(2):e89519. PMID: 24586843, PMCID: PMC3933592 2014 Orgel JP, Irving TC. Advances in Fiber Diffraction of Macromolecular Assembles. Encyclopedia of Analytical Chemistry. 1-26. 2012 Sampath S, Isdebski T, Jenkins JE, Ayon JV, Henning RW, Orgel JP, Antipoa O, Yarger JL. X-ray diffraction study of nanocrystalline and amorphous structure within major and minor ampullate dragline spider silks. Soft matter. 8(25):6713-6722. NIHMSID: NIHMS380877 PMID: 23569461, PMCID: PMC3617558 2012 Bertassoni LE, Orgel JP, Antipova O, Swain MV. The dentin organic matrix -limitations of restorative dentistry hidden on the nanometer scale. Acta biomaterialia. 8(7):2419-33. PMID: 22414619, PMCID: PMC3473357 2012 Antipova O, Orgel JP. Non-enzymatic decomposition of collagen fibers by a biglycan antibody and a plausible mechanism for rheumatoid arthritis. PloS one. 7(3):e32241. PMID: 22427827, PMCID: PMC3302792 2011 Landahl EC, Antipova O, Bongaarts A, Barrea R, Berry R, Binder LI, Irving T, Orgel J, Vana L, Rice SE. X-ray diffraction from intact tau aggregates in human brain tissue. Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment. 649(1):184-187. NIHMSID: NIHMS263705 PMID: 21876609, PMCID: PMC3162212 2011 Cloe AL, Orgel JP, Sachleben JR, Tycko R, Meredith SC. The Japanese mutant Aβ (ΔE22-Aβ(1-39)) forms fibrils instantaneously, with low-thioflavin T fluorescence: seeding of wild-type Aβ(1-40) into atypical fibrils by ΔE22-Aβ(1-39). Biochemistry. 50(12):2026-39. NIHMSID: NIHMS430818 PMID: 21291268, PMCID: PMC3631511 2011 Orgel JP, San Antonio JD, Antipova O. Molecular and structural mapping of collagen fibril interactions. Connective tissue research. 52(1):2-17. PMID: 21182410 2011 Orgel JP, Antipova O, Sagi I, Bitler A, Qiu D, Wang R, Xu Y, San Antonio JD. Collagen fibril surface displays a constellation of sites capable of promoting fibril assembly, stability, and hemostasis. Connective tissue research. 52(1):18-24. NIHMSID: NIHMS342341 PMID: 21117898, PMCID: PMC3244825 2011 San Antonio JD, Schweitzer MH, Jensen ST, Kalluri R, Buckley M, Orgel JP. Dinosaur peptides suggest mechanisms of protein survival. PloS one. 6(6):e20381. PMID: 21687667, PMCID: PMC3110760 2010 Antipova O, Orgel JP. In situ D-periodic molecular structure of type II collagen. The Journal of biological chemistry. 2010; 285(10):7087-96. PMID: 20056598, PMCID: PMC2844158 2009 Orgel JP, Eid A, Antipova O, Bella J, Scott JE. Decorin core protein (decoron) shape complements collagen fibril surface structure and mediates its binding. PloS one. 4(9):e7028. PMID: 19753304, PMCID: PMC2737631 2009 Tycko R, Sciarretta KL, Orgel JP, Meredith SC. Evidence for novel beta-sheet structures in Iowa mutant beta-amyloid fibrils. Biochemistry. 48(26):6072-84. NIHMSID: NIHMS153357 PMID: 19358576, PMCID: PMC2910621 2009 Orgel JP. On the molecular packing of collagen. Acta. Cryst. D65:1009-1010. 2008 Sweeney SM, Orgel JP, Fertala A, McAuliffe JD, Turner KR, Di Lullo GA, Chen S, Antipova O, Perumal S, Ala-Kokko L, Forlino A, Cabral WA, Barnes AM, Marini JC, San Antonio JD. Candidate cell and matrix interaction domains on the collagen fibril, the predominant protein of vertebrates. The Journal of biological chemistry. 283(30):21187-97. PMID: 18487200, PMCID: PMC2475701 2008 Perumal S, Antipova O, Orgel JP. Collagen fibril architecture, domain organization, and triple-helical conformation govern its proteolysis. Proceedings of the National Academy of Sciences of the United States of America. 105(8):2824-9. PMID: 18287018, PMCID: PMC2268544 2007 Darnell G, Orgel JP, Pahl R, Meredith SC. Flanking polyproline sequences inhibit beta-sheet structure in polyglutamine segments by inducing PPII-like helix structure. Journal of molecular biology. 374(3):688-704. PMID: 17945257 2007 Twardowski T, Fertala A, Orgel JP, San Antonio JD. Type I collagen and collagen mimetics as angiogenesis promoting superpolymers. Current pharmaceutical design. 13(35):3608-21. PMID: 18220798 2006 Orgel JP. Surface-active helices in transmembrane proteins. Current protein & peptide science. 7(6):553-60. PMID: 17168788