个人简介

1981 B.S. Western Kentucky University 1987 Ph.D. Purdue University 1987-1989 MIT 1989-2006 UC Davis

研究领域

Organic Chemistry

Interest - Synthetics Vectors for non-viral gene therapy Drug delivery Functionalized nanoparticles Synthetic methodology

近期论文

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M Li, D Yang, G Brock, RJ Knipp, M Bousamra, MH Nantz and X-A Fu Breath Carbonyl Compounds as Biomarkers of Lung Cancer Lung Cancer, Submitted. RJ Knipp, M Li, X-A Fu and MH Nantz A Versatile Probe for Chemoselective Capture and Analysis of Volatile Carbonyl Compounds from Exhaled Breath Analyst, Submitted. RJ Knipp, SJ Mattingly and MH Nantz Magnetic Field-Induced Hydrolysis as a Mechanism for Rapid Release of Nanoparticle-Bound Substrates Advanced Materials Interfaces, Submitted. SJ Mattingly, MG O’Toole, KT James, GJ Clark and MH Nantz Magnetic Nanoparticle–Supported Lipid Bilayers for Drug Delivery Langmuir, In Press (DOI: 10.1021/la504830z) AN Lane, S Arumugam, PK Lorkiewicz, RM Higashi, S Laulhé, MH Nantz, HNB Moseley and TW-M Fan Chemoselective Detection and Discrimination of Carbonyl-Containing Compounds in Metabolite Mixtures by 1H-Detected 15N NMR Magnetic Resonance in Chemistry, In Press (DOI: 10.1002/mrc.4199) ACG Grodzki, B Poola, N Pasupuleti, MH Nantz, PJ Lein and FA Gorin A Novel Carboline Derivative Inhibits Nitric Oxide Formation in Macrophages Independent of Effects on Tumor Necrosis Factor α and Interleukin-1β Expression Journal of Pharmacology and Experimental Therapeutics, 352, 438-447. KA Kang and MH Nantz Site Specific Fluorescence and Contrast Marker for Same United States Patent No. 8,758,727 Issued: June 24, 2014 M Bousamra, E Schumer, M Li, RJ Knipp, MH Nantz, VH van Berkel and X-A Fu Quantitative Analysis of Exhaled Carbonyl Compounds Distinguishes Benign From Malignant Pulmonary Disease Journal of Thoracic and Cardiovascular Surgery, 148, 1074-1081. SS Gori, P Lorkiewicz, DS Ehringer, AC Belshoff, RM Higashi, TW-M Fan and MH Nantz Profiling Thiol Metabolites and Quantification of Cellular Glutathione using FT-ICR-MS Spectrometry Analytical and Bioanalytical Chemistry, 406, 4371-4379. RJ Knipp, R Estrada, P Sethu and MH Nantz Thermally Induced Substrate Release Via Intramolecular Cyclizations of Amino Esters and Amino Carbonates Tetrahedron, 70, 3422-3429. X-A Fu, RM Higashi and MH Nantz Pre-Concentrator and Method of Using the Same United States Patent No. 8,663,581 Issued: March 4, 2014 X-A Fu, M Li, RJ Knipp, MH Nantz and M Bousamra Noninvasive Detection of Lung Cancer Using Exhaled Breath Cancer Medicine, 5, 174-181. FA Gorin and MH Nantz Inhibitors of Intracellular Urokinase Plasminogen Activator and Methods of Use Thereof United States Patent No. 8,546,322 Issued: October 1, 2013 S Laulhé, TE Geers, X Shi, X Zhang and MH Nantz Electron Ionization-Induced Release of Coded Isotopic Reporter Ions in an m/z Zone of Minimal Interference for Quantifiable Multiplexed GC-MS Analyses Analytical Methods, 5, 4701-4706. M Li, S Biswas, MH Nantz, RM Higashi and X-A Fu A Microfabricated Preconcentration Device for Breath Analysis Sensors and Actuators B: Chemical, 180, 130-136. SJ Mattingly, T Xu, MH Nantz, RM Higashi and TW-M Fan A Carbonyl Capture Approach for Profiling Oxidized Metabolites in Cell Extracts Metabolomics, 8, 989-996. S Laulhé, SS Gori and MH Nantz A Chemoselective, One-Pot Transformation of Aldehydes to Nitriles Journal of Organic Chemistry, 77, 9334-9337. S Laulhé, B Bogdanov, LM Johannes, O Gutierrez, GJ Harrison, DJ Tantillo, X Zhang and MH Nantz Fragmentation of Oxime and Silyl-Oxime Ether Odd-Electron Positive Ions by the McLafferty Rearrangement: New Insights on Structural Factors that Promote alpha-beta Fragmentation Journal of Mass Spectrometry, 47, 676-686. KA Kang, J Wang, MG O'Toole, MH Nantz, JD Moore, S Laulhé and S Achilefu Sensitivity Enhancement of NIR Fluorescence Contrast Agent Utilizing Gold Nanoparticles Advances in Experimental Medicine and Biology, 737, 285-291. AP Massey, WR Harley, N Pasupuleti, FA Gorin and MH Nantz 2-Amidino Analogs of Glycine-Amiloride Conjugates: Inhibitors of Urokinase-type Plasminogen Activator Bioorganic Medicinal Chemistry Letters, 22, 2635-2639.