个人简介
教育经历:
1993 - 1996 , 工学博士 , 应用化学 , 北京理工大学
1990 - 1993 , 理学硕士 , 物理化学 , 吉林大学
1986 - 1990 , 理学学士 , 有机化学 , 辽宁大学
工作经历:
2000 - 至今 , 副教授 , 北京大学生命科学学院
1998 - 2000 , 讲师 , 北京大学生命科学学院
1996 - 1998 , 博士后 , 军事医学科学院药物与毒物研究所
研究领域
1. 利用泛癌基因组数据整合分析复杂疾病中的遗传机制;
2. 系统注释和分析转运蛋白的功能及与复杂疾病的关系;
3. 构建和拓扑分析代谢转运网络;
4. 计算模拟分析生物大分子的结构和功能;
5. 验证MSKCC Nomogram预后分析模型在中国结肠癌和胃癌人群中的的适用度
6. 研究circular RNA作为竞争性内源RNA在癌症转移中的调控作用
近期论文
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1. Peng L, Zhao M, Liu T, Chen J, Gao P, Chen L, Xing P, Wang Z, Di J, Xu Q, Hong Qu*, Jiang B, Su X. A stop-gain mutation in GXYLT1 promotes metastasis of colorectal cancer via the MAPK pathway. Cell Death Dis. 2022 Apr 22;13(4):395. doi: 10.1038/s41419-022-04844-3.
2. Liu Y, Chen L, Liu T, Su X, Peng L, Chen J, Tan F, Xing P, Wang Z, Di J, Jiang B, Hong Qu*. Genome-wide circular RNA (circRNA) and mRNA profiling identify a circMET-miR-410-3p regulatory motif for cell growth in colorectal cancer. Genomics. 2022 Jan;114(1):351-360. doi: 10.1016/j.ygeno.2021.11.038.
3. Zhao M, Liu Y, Hong Qu*. circExp database: an online transcriptome platform for human circRNA expressions in cancers. Database (Oxford). 2021 Jul 23;2021:baab045. doi: 10.1093/database/baab045.
4. Zhao M, Liu Y, Ding G, Qu D, Hong Qu*. Online database for brain cancer-implicated genes: exploring the subtype-specific mechanisms of brain cancer. BMC Genomics. 2021 Jun 18;22(1):458. doi: 10.1186/s12864-021-07793-x.
5. Min Zhao, Hong Qu*, circVAR database: genome-wide archive of genetic variants for human circular RNAs. BMC Genomics. 2020 Oct 29; 21(1): 750. doi: 10.1186/s12864-020-07172-y.
6. Min Zhao, Yining Liu, Chong Zheng, Hong Qu*, dbEMT 2.0: An updated database for epithelial-mesenchymal transition genes with experimentally verified information and precalculated regulation information for cancer metastasis, Journal of Genetics and Genomics, 2019 Dec 20;46(12):595-597.
7. Haokai Sang, Shuli Guo, Hong Qu*, Min Zhao*, and Dacheng Qu*, Development of omics data based survival models for four female cancers using machine learning approaches. Sci Sin Vitae, 2019, 49, doi: 10.1360/N052018-00265.
8. Yining Liu, Mingyu Luo, Qijun Li, Jiachun Lu, Min Zhao*, and Hong Qu*, CIGene: a literature-based online resource for cancer initiation genes. BMC Genomics. 2018; 19: 552.
9. Yining Liu, Mingyu Luo, Zhaochen Jin, Min Zhao*, and Hong Qu*, dbLGL: an online leukemia gene and literature database for the retrospective comparison of adult and childhood leukemia genetics with literature evidence. Database (Oxford). 2018. doi: 10.1093/database/bay062.
10. Yining Liu, Zhe Li, Jiachun Lu, Min Zhao*, Hong Qu*. CMGene: A literature-based database and knowledge resource for cancer metastasis genes. J Genet Genomics. 44(5):277-279 (2017)
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