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个人简介

教育经历: 2007 - 2009, 访问学者 , 生物科学系 , 美国加州大学圣地亚哥分校 2001 - 2003, 博士后 , 北京大学生命科学学院 1996 - 2001, 毕业 , 植物遗传育种 , 南京农业大学农学院,农学博士 1992 - 1996, 毕业 , 植物遗传育种 , 南京农业大学农学院,农学学士 工作经历: 2015 - 至今,教授,北京大学生命科学学院 2006 - 2015,副教授,北京大学生命科学学院 2001 - 2006, 讲师,北京大学生命科学学院 荣誉奖励: 2017年获国家杰出青年基金资助 2010年教育部新世纪优秀人才 2012年北京大学绿叶生物医药杰出青年学者奖 学术任职: 2013-至今 中国植物学会植物生理及分子生物学专业委员会,委员 2018-至今 北京市植物学会第十届理事会,理事

研究领域

植物叶片发育保守转录调控分子机制的研究: 叶片是光合作用的主要器官。叶片在地球上的出现彻底改变了地球表面和大气的环境,也改变了植物和动物的进化方向。早在300多年前,德国著名的自然科学家兼哲学家戈特弗里德•威廉•莱布尼茨 (Gottfried Wilhelm Leibniz) 就指出世界上没有两片完全相同叶片的自然现象,叶片形态的多样性使其成为重要的分类依据,但叶片也有统一性,比如很多叶片都是平整的。叶片如何进化而来?叶片如何根据不同的环境形成多种多样的大小和形态?又怎样形成平整的结构为进行光合作用来高效捕获光能?这些科学问题还远没有研究清楚。本课题组的研究方向主要是根据这些科学问题,以模式植物拟南芥和水稻为材料,利用遗传学、分子生物学和生物化学的方法,寻找和克隆调控叶片发育相关的重要保守关键基因,研究重要转录因子TCP、EXB蛋白家族、转录抑制因子TIE蛋白家族以及与染色质重塑因子相关的TPL/TPRs蛋白家族在调控叶片和其他器官发育中的保守分子机制,完善调控叶片发育的分子调控网络,为叶片与侧枝间的进化关系提供可能的分子证据,加深理解叶片形成平整以及不同形态和大小的分子机理,为通过分子设计育种改造植物株型和叶片大小和形态来提高农作物产量提供理论基础。

近期论文

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1. Wenqi Qin, Ning Wang, Qi Yin, Huiling Li, Ai-Min Wu and Genji Qin* (2022) Activation tagging identifies WRKY14 as a repressor of plant thermomorphogenesis in Arabidopsis. Molecular Plant 15(11):1725-1743. 2. Qing He, Rongrong Yuan, Tiantian Zhang, Fengying An, Ning Wang, Jingqiu Lan, Xinxue Wang, Zeliang Zhang, Yige Pan, Xuanzhi Wang, Jinzhe Zhang, Dongshu Guo and Genji Qin* (2022) Arabidopsis TIE1 and TIE2 transcriptional repressors dampen cytokinin response during root development. Science Advances 8(36): eabn5057. 3. Xinhui Zheng, Jingqiu Lan, Hao Yu, Jingzhe Zhang, Yi Zhang, Yongmei Qin, Xiao-Dong Su and Genji Qin* (2022) Arabidopsis transcription factor TCP4 represses chlorophyll biosynthesis to prevent petal greening. Plant Communications 4: 100309. 4. Jingqiu Lan, Jinzhe Zhang, Rongrong Yuan, Hao Yu, Linhua Sun, Fengying An, Haodong Chen, Yue Zhou, Weiqiang Qian, Hang He and Genji Qin* (2021) TCP transcription factors suppress cotyledon trichomes by impeding a cell differentiation-regulating complex. Plant Physiology 186: 434-451. 5. Jingqiu Lan and Genji Qin* (2020) The regulation of CIN-like TCP transcription factors. International Journal of Molecular Sciences 21: 4498. 6. Xiang Han, Hao Yu, Rongrong Yuan, Yan Yang, Fengying An, Genji Qin* (2019) Arabidopsis transcription factor TCP5 controls plant thermomorphogenesis by positively regulating PIF4 activity. iScience 15: 611-622. 7. Rongrong Yuan, Jingqiu Lan, Yuxing Fang, Hao Yu, Jinzhe Zhang, Jiaying Huang and Genji Qin* (2018) The Arabidopsis USL1 controls multiple aspects of development by affecting late endosome morphology. New Phytologist 219: 1388-1405. 8. Yan Yang#, Michael Nicolas#, Jinzhe Zhang, Hao Yu, Dongshu Guo, Rongrong Yuan, Tiantian Zhang, Jianzhao Yang, Pilar Cubas*, Genji Qin* (2018) The TIE1 transcriptional repressor controls shoot branching by directly repressing BRANCHED1 in Arabidopsis. PLoS Genetics 14(3): e1007296. 9. Jinzhe Zhang, Baoye Wei, Rongrong Yuan, Jianhui Wang, Mingxin Ding, Zhuoyao Chen, Hao Yu, Genji Qin* (2017). The Arabidopsis RING-type E3 ligase TEAR1 controls leaf development by targeting the TIE1 transcriptional repressor for degradation. Plant Cell 29(2): 243-259. 10. Dongshu Guo, Genji Qin* (2016). EXB1/WRKY71 transcription factor regulates both shoot branching and responses to abiotic stresses. Plant Signaling & Behavior. 11(3): e1150404. 11. Shibai Li, Xiaochen Wang, Shan He, Jieru Li, Qingpei Huang, Takato Imaizumi, Leqing Qu, Genji Qin, Li-Jia Qu, and Hongya Gu* (2016). CFLAP1 and CFLAP2 Are Two bHLH Transcription Factors Participating in Synergistic Regulation of AtCFL1-Mediated Cuticle Development in Arabidopsis. PLoS Genetics. 12(1): e1005744. 12. Dongshu Guo, Jinzhe Zhang, Xinlei Wang, Xiang Han, Baoye Wei, Jianqiao Wang, Boxun Li, Hao Yu, Qingpei Huang, Hongya Gu, Li-Jia Qu, Genji Qin* (2015). The WRKY transcription factor WRKY71/EXB1 controls shoot branching by transcriptionally regulating RAX genes in Arabidopsis. Plant Cell 27: 3112-3127. (cover story) 13. Qing Liu, Gezhi Shen, Keqin Peng, Zhigang Huang, Jianhua Tong, Mohammed Humayun Kabir, Jianhui Wang, Jingzhe Zhang, Genji Qin* and Langtao Xiao* (2015). The alteration in the architecture of a T-DNA insertion rice mutant osmtd1 is caused by up-regulation of MicroRNA156f. Journal of Integrative Plant Biology 57(10):819-829. 14. Baoye Wei, Jinzhe Zhang, Changxu Pang, Hao Yu, Dongshu Guo, Hao Jiang, Mingxin Ding, Zhuoyao Chen, Qing Tao, Hongya Gu, Li-Jia Qu, Genji Qin* (2015). The molecular mechanism of SPOROCYTELESS/NOZZLE in controlling Arabidopsis ovule development. Cell Research 25:121-134. 15. Yan Yang, Bin Ou, Jinzhe Zhang, Hongya Gu, Genji Qin and Li-Jia Qu (2014). The Arabidopsis Mediator subunit MED16 regulates iron homeostasis by associating with EIN3/EIL1 through subunit MED25. Plant Journal 77(6):838-851. 16. Ruixi Li, Jieru Li, Shibai Li, Genji Qin, Ondrej Novak, Ales Pencik, Karin Ljung,Takashi Aoyama, Jingjing Liu, Angus Murphy, Hongya Gu, Tomohiko Tsuge, Li-Jia Qu (2014). ADP1 Affects Plant Architecture by Regulating Local Auxin Biosynthesis. PLOS Genetics 10(1): e1003954. 17. Jin Miao#, Dongshu Guo#, Jinzhe Zhang#, Qingpei Huang#, Genji Qin#, Xin Zhang,Jianmin Wan, Hongya Gu, Li-Jia Qu* (2013). Targeted mutagenesis in rice using CRISPR-Cas system. Cell Research 23(10):1233-1236. 18. Tong Wei, Bin Ou, Jinbin Li, Yang Zhao, Dongshu Guo, Youyong Zhu, Zhangliang Chen, Hongya Gu, Chengyun Li*, Genji Qin* and Li-Jia Qu* (2013). Transcriptional profiling of rice early response to Magnaporthe oryzae identified OsWRKYs as important regulators in rice blast resistance. PLoS ONE 8(3): e59720. 19. Qing Tao, Dongshu Guo, Baoye Wei, Fan Zhang, Changxu Pang, Hao Jiang, Jinzhe Zhang, Tong Wei, Hongya Gu, Li-Jia Qu, Genji Qin* (2013). The TIE1 Transcriptional Repressor Links TCP Transcription Factors with TOPLESS/TOPLESS-RELATED Corepressors and Modulates Leaf Development in Arabidopsis. Plant Cell 25: 421-437 20. Yan Chen, Zhangliang Chen, Juqing Kang, Dingming Kang, Hongya Gu, Genji Qin* (2013). AtMYB14 Regulates Cold Tolerance in Arabidopsis. Plant Molecular Biology Reporter 31: 87-97. 21. Mingqiu Dai, Chen Zhang, Urszula Kania, Fang Chen, Qin Xue, Tyra Mccray, Gang Li, Genji Qin, Michelle Wakeley, William Terzaghi, ,Jianmin Wan, Yunde Zhao, Jian Xu, Jiří Friml, Xing Wang Deng and Haiyang Wang (2012). A novel PP6-type phosphatase holoenzyme directly regulates PIN phosphorylation and auxin efflux in Arabidopsis. Plant Cell 24: 2497-2514. 22. Wei-ying Wang, Li Zhang, Shufan Xing, Zhiqiang Ma, Jingjing Liu, Hongya Gu, Genji Qin* and Li-jia Qu* (2012). Arabidopsis AtVPS15 plays essential roles in pollen germination possibly by interacting with AtVPS34. Journal of Genetics and Genomics 39: 81-92. 23. Yang Zhao, Tong Wei, Kang-Quan Yin, Zhangliang Chen, Hongya Gu, Li-Jia Qu and Genji Qin*(2012). Arabidopsis RAP2.2 plays an important role in plant resistance to Botrytis cinerea and ethylene responses. New Phytologist 195: 450-460. 24. Renhong Wu, Shibai Li, Shan He, Friedrich Waßmann, Caihong Yu, Genji Qin, Lukas Schreiber, Li-Jia Qu, and Hongya Gu (2011). CFL1, a WW domain protein, regulates cuticle development by modulating the function of HDG1, a Class IV homeodomain transcription factor, in rice and Arabidopsis. Plant Cell 23(9): 3392-3411. 25. Yu Luo, Genji Qin, Jun Zhang, Yuan Liang,Yingqi Song,Meiping Zhao,Tomohiko Tsuge,Takashi Aoyama,Jingjing Liu,Hongya Gu, and Li-Jia Qu (2011). D-myo-Inositol-3-Phosphate Affects Phosphatidylinositol-Mediated Endomembrane Function in Arabidopsis and Is Essential for Auxin-Regulated Embryogenesis. Plant Cell 23(4): 1352-72. 26. Yanxia Zhang, Renhong Wu, Genji Qin, Zhangliang Chen, Hongya Gu, Li-Jia Qu (2011). Over-expression of WOX1 leads to defects in meristem development and polyamine homeostasis in Arabidopsis. Journal of Integrative Plant Biology 53: 493-506. 27. Lihua Han, Genji Qin, Dingming Kang, Zhangliang Chen, Hongya Gu, Li-Jia Qu (2010). A nuclear-encoded mitochondrial gene AtCIB22 is essential for plant development in Arabidopsis. Journal of Genetics and Genomics 37: 667-683. 28. Shufan Xing, Jin Miao, Shuang Li, Genji Qin, Si Tang, Haoni Li, Hongya Gu, Li-Jia Qu, (2010) Disruption of the 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) results in albino, dwarf and defects in trichome initiation and stomata closure in Arabidopsis. Cell Research 20:688-700.

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