个人简介
教育经历:
2000 - 2002 , 博士后,日本通商产业省生命工学工业技术研究所(Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Central 6, Higashi, Tsukuba, Ibaraki, Japan)
1996 - 1999 , 医学博士,日本筑波大学基础医学院,生物化学与分子肿瘤学(Department of Biochemistry and Molecular Oncology, Institute of Basic Medical Sciences ,University of Tsukuba, Tsukuba, Ibaraki , Japan)
1988 - 1991 , 医学硕士,河北医科大学基础医学院,生物化学
1981 - 1986 , 医学学士, 河北医科大学, 医学系
工作经历:
2011 - 至今 , 博士生导师 , 北京大学生命科学学院
2002 - 至今 , 副教授 , 北京大学生命科学学院
荣誉奖励:
首届“北京大学参政议政服务发展同心奖”先进个人, 2022
北京大学教学优秀奖 ,2018
北京大学优秀班主任 , 2017
北京大学东宝教师奖 , 2016
北京大学东宝教师奖 , 2011
北京大学优秀班主任 , 2008
近期论文
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1. Du LP, Li JY, Tian YL, Feng RQ*. Pleckstrin-2-promoted PPM1B degradation plays an important role in transforming growth factor-β-induced breast cancer cell invasion and metastasis. Cancer Science. 2023: doi: 10.1111/cas.15791.
2. Yang L, Li RC, Xiang B, Li YC, Wang LP, Guo YB, Liang JH, Wang XT, Hou T, Xing X, Zhou ZQ, Ye H, Feng RQ, Lakatta EG, Chai Z, Wang SQ* (2021) Transcriptional regulation of intermolecular Ca2+ signaling in ground squirrel cardiomyocytes: the myocardin- junctophilin axis. Proc. Natl. Acad. Sci. U.S.A. 2021;118:/e2025333118. Doi:10.1073/pnas.2025333118.
3.Cheng H, Wang S, Feng R*. STIM1 plays an important role in TGF-β-induced suppression of breast cancer cell proliferation. Oncotarget. 2016, 7(13): 16866-16878. DOI: 10.18632/oncotarget.7619 .
4.Yu Y, Yang R, Zhao X, Qin D, Liu Z, Liu F, Song X, Li L, Feng R*, Gao N*. Abrin P2 Suppresses Proliferation and Induces Apoptosis of Colon Cancer Cells via Mitochondrial Membrane Depolarization and Caspase Activation. Acta Biochimica et Biophysica Sinica, 2016, 48(5): 420-429.doi: 10.1093/abbs/gmw023
5. Mahdi SHA.,Cheng H., Li J.,Feng R*. The effect of TGF-beta-induced epithelial-mesenchymal transition on the expression of intracellular calcium-handling proteins in T47D and MCF-7 human breast cancer cells. Archives of Biochemistry and Biophysics, 2015, 583: 18-26. doi: 10.1016/j.abb.2015.07.008
6. Liu X; Du L; Feng R* , c-Src regulates cell cycle proteins expression through protein kinase B/glycogen synthase kinase 3 beta and extracellular signal-regulated kinases 1/2 pathways in MCF-7 cells , Acta Biochimica et Biophysica Sinica , 2013 , 45: 586-592. doi: 10.1093/abbs/gmt042.
7. Liu X, Feng R* , Inhibition of epithelial to mesenchymal transition in metastatic breast carcinoma cells by c-Src suppression , Acta Biochimica et Biophysica Sinica , 2010 , 42(7): 496-501. DOI: 10.1093/abbs/gmq043.
8. Liu X,Feng R*, Du L. , The role of enoyl-CoA hydratase short chain 1 and peroxiredoxin 3 in PP2-induced apoptosis in human breast cancer MCF-7 cells. , FEBS Letters. , 2010 , 584: 3185-3192. DOI: 10.1016/j.febslet.2010.06.002
9. Feng R*, Guo Z , Li J. , Efficient purification of GP-1D8 glycoprotein from human breast carcinoma tissue by immunoaffinity chromatography , Preparative Biochemistry and Biotechnology , 2008 , 38(4): 321-333
10. Feng R*, Liu X, Guo Z , Li J. Purification and characterization of 66-kDa glycoprotein from human breast carcinoma , Cancer Sci , 2007 , 98: 1344-1349
11. Feng R*, Du L, Guo Z , In vitro cultivation and differentiation of fetal liver stem cells from mice . Cell Res. , 2005 , 15(5):401-405
12. Feng R, Kabayama A, Uchida K, Hoshino H, Miwa M. Cell-free entry of human T-cell leukemia virus type 1 to mouse cells. , Jpn J Cancer Res , 2001 , 92(4):410-6.
13. Sun B, Feng R, Shoda M, Nitta T, Hanai S, Uchida K,Hoshino H, Miwa M. Cell-free HTLV-1 infection to mouse cells and expression , AIDS Research and Human Retrovirus , 2001 , 17(Suppl.1): S46-46
14. Feng R, Tanaka M, Abe H, Arashi N, Sun B, Uchida K, Miwa M. , Human T-cell leukemia virus type 1 can infect a wide variety of cells in mice , Jpn J Cancer Res , 1999 , 90(1):48-54
15. Fang J, Kushida S, Feng R, Tanaka M, Kawamura T, Abe H, Maeda N, Onobori M, Hori M, Uchida K, Miwa M. Transmission of human T-cell leukemia virus type 1 to mice . J Virol , 1998 , 72(5):3952-7.
16. Fang J, Kushida S, Feng R, Tanaka M, Kikukawa H, Kawamura T, Uchida K, Miwa M. , Integration of HTLV-1 provirus into mouse transforming growth factor-alpha gene , Biochem Biophys Res Commun , 1997 , 233(3):792-5.