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个人简介

教育经历 2012.02 新泽西州立大学 博士 环境科学/暴露评估 导师:Junfeng (Jim) Zhang,博士,杜克大学 2006.07 北京大学 硕士 环境科学 导师:朱彤,博士,北京大学 2003.07 北京大学 学士 环境科学 导师:朱彤,博士,北京大学 工作经历 2022.07- 北京大学环境科学与工程学院 长聘制副教授 2016.07-2022.07 北京大学环境科学与工程学院 预聘制助理教授 2013.10-2016.06 杜克大学尼古拉斯环境学院 博士后 2012.02-2013.09 南加州大学Keck医学院 博士后 2006.09-2012.01 新泽西州立大学公共卫生学院 研究助理

研究领域

大气污染暴露与人体心肺健康的关联和效应机制 大气污染暴露与健康效应生物标志物的分析方法开发 应用生物标志物揭示大气污染暴露影响人体心肺健康的作用机制 开展实验性人群研究,强化大气污染与人体健康间的因果性证据

近期论文

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Li, S.; Cao, S.; Duan, X.; Zhang, Y.; Gong, J.; Xu, X.; Guo, Q.; Meng, X.; Zhang, J. Household mold exposure in association with childhood asthma and allergic rhinitis in a northwestern city and a southern city of China. Journal of Thoracic Disease, 2022, 14: 1725-1737. Xu, Y.; Han, Y.; Wang, Y.; Gong, J.; Li, H.; Wang, T.; Chen, X.; Chen, W.; Fan, Y.; Qiu, X.; Wang, J.; Xue, T.; Li, W.; Zhu, T.*, Ambient air pollution and atherosclerosis: a potential mediating role of sphingolipids. Arteriosclerosis, Thrombosis, and Vascular Biology, doi: 10.1161/ATVBAHA.122.317753. Xue, T.; Geng, G.; Meng, X.; Xiao, Q.; Zheng, Y.; Gong, J.; Liu, J.; Wan, W.; Zhang, Q.; Kan, H.; Zhang, S.; Zhu, T*. New WHO Global Air Quality Guidelines Help Prevent Premature Deaths in China. National Science Review, 2022, https://doi.org/10.1093/nsr/nwac055. Shi, S.*; Zhang, J.; Gong, J.; Zhao, B*. Benefits from Disease Burden Reduction for Type-2 Diabetes and Obesity by Comprehensive Regulatory Restrictions on Phthalates Use in China. One Earth, 2022, 5: 380-391. Cao, S.#; Xie, M.#; Jia, C.; Zhang, Y.; Gong, J.; Wang, B.; Qin, N.; Zhao, L.; Yu, D.; Duan, X.*, Household second-hand smoke exposure and stunted growth among Chinese school-age children. Environmental Science and Innovation, 2022, 27: 102521. Xu, Y.; Chen, X.; Han, Y.; Chen, W.; Wang, T.; Gong, J.; Fan, Y.; Zhang, H.; Zhang, L.; Li, H.; Wang, Q.; Yao, Y.; Xue, T.; Wang, J.; Qiu, X.; Que, C.; Zheng, M.; Zhu, T.*, Ceramide metabolism mediates the impaired glucose homeostasis following short-term black carbon exposure: A targeted lipidomic analysis. Science of the Total Environment, 2022, 829: 154657. Jia, S.; Setyawati, M.; Liu, M.; Xu, T.; Loo, J.; Yan, M.; Gong, J.; Chotirmall, S.; Demokritou, P.; Ng, K.*; Fang, M.*, Association of nanoparticle exposure with serum metabolic disorders of healthy adults in printing centers. Journal of Hazardous Materials, 2022, 432: 128710. Yan, M.; Xie, Y.; Zhu, H.; Ban, J.; Gong, J.; Li, T.*, The exceptional heatwaves of 2017 and all-cause mortality: An assessment of nationwide health and economic impacts in China. Science of the Total Environment, 2022, 812: 152371. Li, S.; Wu, W.; Wang, G.; Zhang, X.; Guo, Q.; Wang, B.; Cao, S.; Yan, M.; Pan, X.; Xue, T.; Gong, J.; Duan, X*., Association between exposure to air pollution and risk of allergic rhinitis: A systematic review and meta-analysis. Environmental Research, 2022, 205: 112472. Xu, Y.; Li, H.; Han, Y.; Wang, T.; Wang, Y.; Gong, J.; Gao, K.; Chen, W.; Li, W.; Zhang, H.; Wang, J.; Qiu, X.; Zhu, T*., A simple and rapid method for extraction and measurement of circulating sphingolipids using LC-MS/MS: a targeted lipidomic analysis. Analytical and Bioanalytical Chemistry, 2022, 414: 2041-2054. Xu, R.; Meng, X.; Pang, Y.; An, H.; Wang, B.; Zhang, L.; Ye, R.; Ren, A.; Li, Z.*; Gong, J.*, Associations of maternal exposure to 41 metals during early pregnancy with the risk of spontaneous preterm birth: Does oxidative stress or DNA methylation play a crucial role? Environment International, 2022, 158: 106966. Wang, T.; Han, Y.; Li, H.; Fang, Y.; Liang, P.; Wang, Y.; Chen, X.; Qiu, X.; Gong, J.; Li, W.; Zhu, T*., Fine particulate matter and vasoactive 20-hydroxyeicosatetraenoic acid: insights into the mechanisms of the prohypertensive effects of particulate air pollution. Science of the Total Environment, 2022, 806 (Pt 3): 151298. Fang, M.; Hu, L.; Chen, D.; Guo, Y.; Liu, J.; Lan, C.; Gong, J.*; Wang, B.*, Exposome in human health: Utopia or wonderland? The Innovation, 2021, 2: 100172. (SCI citation: 3) Shi, Y.#; Han, Y. #; Wang, Y.#; Qi, L.; Chen, X.; Chen, W.; Li, W.; Zhang, H.; Zhu, T.; Gong, J.*, Serum Branched-Chain Amino Acids Modifies the Associations Between Air Pollutants and Insulin Resistance. Ecotoxicology and Environmental Safety, 2021, 225: 112780. Wang, T.#; Han, Y.#; Li, H.; Wang, Y.; Chen, X.; Chen, W.; Qiu, X.; Gong, J.; Li, W.; Zhu, T.*, Proinflammatory lipid signals trigger the health effects of air pollution in individuals with prediabetes. Environmental Pollution, 2021, 290: 118008. Li, S.#; Cao, S.#; Duan, X.*; Zhang, Y.; Gong, J.; Xu, X.; Guo, Q.; Meng, X.; Bertrand, M.; Zhang, J., Children’s lung function in relation to changes in socioeconomic, nutritional, and household factors over 20 years in Lanzhou. Journal of Thoracic Disease, 2021, 13: 4574-4588. Cao, S.; Wen, D.; Li, S.; Guo, Q.; Duan, X.*; Gong, J.; Xu, X.; Meng, X.; Qin, N.; Wang, B.; Zhang, J. Changes in children's lung function over two decades in relation to socioeconomic, parental and household factors in Wuhan, China. Journal of Thoracic Disease, 2021, 13: 4601-4613. He, L.; Hu, X.; Day, D.; Yan, M.; Teng, Y.; Liu, X.; Yan, E.; Xiang, J.; Qiu, X.; Mo, J.; Zhang, Y.; Zhang, J.; Gong, J.*, The Associations of Nitrated Polycyclic Aromatic Hydrocarbon Exposures with Plasma Glucose and Amino Acids. Environmental Pollution, 2021, 289: 117945. Yan, M.; Gong, J.*, Liu, Q.; Li W.; Duan, X.; Cao, S.; Li, S.; He, L.; Yin, Z.; Lin, W.; Zhang, J., The effects of indoor and outdoor air pollution on the prevalence of adults’ respiratory diseases in four Chinese cities: a comparison between 2017-2018 and 1993-1996. Journal of Thoracic Disease, 2021, 13: 4560-4573. Meng, X.#; Cao, S.#; Li, S.; Yan, M.; Guo, Q.; Gong, J.*; Liu, Q.; Zhang, J.; Duan, X.*, Household environmental factors and children’s respiratory health: comparison of two cross-sectional studies over twenty-five years in Wuhan, China. Journal of Thoracic Disease, 2021, 13: 4589-4600. Jiang, M.; Meng, X.; Qi, L.; Hu, X.; Xu, R.; Yan, M.; Shi, Y.; Meng, X.; Li, W.; Xu, Y.; Chen, S.; Zhu, T.; Gong, J.*, The health effects of wearing facemasks on cardiopulmonary system of healthy young adults: a double-blinded, randomized crossover trial. International Journal of Hygiene and Environmental Health, 2021, 236: 113806. Huang, L.; Cheng, H.; Ma, S.; He, R.; Gong, J.; Li, G.; An, T.*, The exposures and health effects of benzene, toluene and naphthalene for Chinese chefs in multiple types kitchen. Environment International, 2021, 156: 106721. (SCI citation: 1) Hu, X.#; Yan, M.#; He, L.; Qiu, X.; Zhang, J.; Zhang Y.; Mo, J.; Day, D.; Xiang, J.; Gong, J.*, Associations between time-weighted personal air pollution exposure and amino acid metabolism in healthy adults. Environment International, 2021,156:106623. (SCI citation: 1) Jiang X.#; Han, Y.#; Qiu, X.*; Chai, Q.; Zhang, H.; Chen, X.; Cheng, Z.; Wang, Y.; Fan, Y.; Xue, T.; Li, W.; Gong, J.; Zhu, T., Organic Components of Personal PM2.5 Exposure Associated with Inflammation: Evidence from an Untargeted Exposomic Approach. Environmental Science & Technology, 2021, 55: 10589-10596. He, L.; Lin, Y.; Day, D.; Teng, Y.; Wang, X.; Liu, X.; Yan, E.; Gong, J.; Qin, J.; Wang, X.; Xiang, J.; Mo, J.; Zhang, Y.; Zhang, J.*, Nitrated Polycyclic Aromatic Hydrocarbons and Arachidonic Acid Metabolisms Relevant to Cardiovascular Pathophysiology: Findings from a Panel Study in Healthy Adults. Environmental Science & Technology, 2021, 55: 3867-3875. (SCI citation: 5) Lu, Y.#; Wu, J.#; Gu, W.; Huang, Z.; Shu, Z.; Huang, M.; Chen, J.; Zhou, M.; Bai, Y.; Chen, X.; Xiao, Y.; Shen, M.; Luo, D; Deng, Q.; Chai, L.; He, M.; Gong, J.; Yuan, H.; Xu, Q.; Cai, J.*, Single-cell transcriptomics uncovers phenotypic alterations in the monocytes in a Chinese population with chronic cadmium exposure. Ecotoxicology and Environmental Safety, 2021, 211: 111881. Wang, T.#; Han, Y.#; Li, H.; Wang, Y.; Xue, T.; Chen, X.; Chen, W.; Fan, Y.; Qiu, X.; Gong, J.; Xu, Y.; Wang, J.; Li, W.; Zhu, T.*, Changes in bioactive lipid mediators in response to short-term exposure to ambient air particulate matter: A targeted lipidomic analysis of oxylipin signaling pathways. Environment International, 2021,147: 106314. (SCI citation: 2) Liu, M.; Jia, S.; Dong, T.; Zhao, F.; Xu, T.; Yang, Q.; Gong, J.; Fang, M.*, Metabolomics and transcriptomic analysis of MCF-7 cells exposed to 23 chemicals at human-relevant levels: estimation of individual chemical contribution to effects. Environmental Health Perspectives, 2020, 128: 127008. (SCI citation: 6) Li, S.#; Cao, S. #; Duan, X.*; Zhang, Y.; Gong, J.; Xu, X.; Guo, Q.; Meng, X.; Bertrand, M.; Zhang, J., Long-term exposure to PM2.5 and Children’s lung function: a dose-based association analysis. Journal of Thoracic Disease, 2020, 12: 6379-6395. (SCI citation: 3) Cao, S.; Wen, D.; Li, S.; Duan, X.*; Zhang, Y.; Gong, J.; Guo, Q.; Xu, X.; Qin, N.; Meng, X.; Zhang, J., Changes in children’s asthma prevalence over two decades in Lanzhou: effects of socioeconomic, parental and household factors. Journal of Thoracic Disease, 2020, 12: 6365-6378. (SCI citation: 5) Wang, T.; Li, H.; Han, Y.; Wang, Y.; Gong, J.; Gao, K.; Li, W.; Zhang, H.; Wang, J.; Qiu, X.; Zhu, T.*, A rapid and high-throughput approach to quantify non-esterified oxylipins for epidemiological studies using online SPE-LC-MS/MS. Analytical and Bioanalytical Chemistry, 2020, 412: 7989-8001. (SCI citation: 2) He, L.; Hu, X.; Gong, J.*; Day, D.; Xiang, J.; Mo, J.; Zhang, Y.; Zhang, J.*, Endogenous melatonin mediation of systemic inflammatory responses to ozone exposure in healthy adults. Science of the Total Environment, 2020, 749: 141301. (SCI citation: 3) Yan, M.; Gong, J.*; Liu, Q.; Li W.; Duan, X.; Cao, S.; Li, S.; He, L.; Yin, Z.; Lin, W.; Zhang, J., Prevalence of respiratory diseases in relation to smoking rate in adults in four Chinese cities: A comparison between 2017-2018 and 1993-1996. Journal of Thoracic Disease, 2020, 12: 6315-6326. (SCI citation: 2) Lin, J.#; Lin, W. # *; Yin, Z.; Fu, X.; Mai, D.; Fu, S.; Zhang, J.; Gong, J.; Feng, N.; He, L., Respiratory health effects of residential individual and cumulative risk factors in children living in two cities of the Pearl River Delta Region, China. Journal of Thoracic Disease, 2020, 12: 6342-6355. (SCI citation: 2) Cui, X.; Li, Z.; Teng, Y.; Barkjohn, K.K.; Norris, C.L.; Fang, L.; Daniel, G.N.; He, L.; Lin, L.; Wang, Q.; Day, D.B.; Zhou, X.; Hong, J.; Gong, J.; Li, F.; Mo, J.; Zhang, Y.; Schauer, J. J.; Black, M.S.; Bergin, M.H.; Zhang, J.*, Association between bedroom particulate matter filtration and changes in airway pathophysiology in children with asthma. JAMA Pediatrics, 2020, 174: 533-542. (SCI citation: 24) Hu, X.#; He, L.#; Zhang, J.; Qiu, X.; Zhang, Y.; Mo, J.; Day, D.; Xiang, J.; Gong, J.*, Inflammatory and oxidative stress responses of healthy adults to changes in personal air pollutant exposure. Environment Pollution, 2020, 263:114503. (SCI citation: 12) Liang, W.; Wang, B.; Shen, G.; Cao, S.; Mcswain, B.; Qin, N.; Zhao, L.; Yu, D.; Gong, J.; Zhao, S.; Zhang, Y.; Duan, X.*, Association of solid fuel use with risk of stunting in children living in China, Indoor Air, 2020, 30: 264-274. (SCI citation: 5) He, L.; Cui, X.; Xia, Q.; Li, F.; Mo, J.; Gong J.; Zhang, Y.; Zhang, J.*, Effects of personal air pollutant exposure on oxidative stress: Potential confounding by natural variation in melatonin levels. International Journal of Hygiene and Environmental Health, 2020, 223: 116-123. (SCI citation: 10) Qi, L.; Xu, RW.; Gong, J.*, Monitoring DNA adducts in human blood samples using magnetic Fe3O4@graphene oxide as a nano-adsorbent and mass spectrometry. Talanta, 2020, 209: 120523. (SCI citation: 4) Qi, L. and Gong, J.*, Facile in-situ polymerization of polyaniline-functionalized melamine sponge preparation for mass spectrometric monitoring of perfluorooctanoic acid and perfluorooctane sulfonate from biological samples. Journal of Chromatography A, 2020, 1616: 460777. (SCI citation: 2) Xu, M.; Wang, L.; Wang, M.; Wang, H.; Zhang, H.; Chen, Y.; Wang, X.; Gong, J.; Zhang, J.; Adcock, I.; Chung, K.; Li, F.*, Mitochondrial ROS and NLRP3 inflammasome in acute ozone-induced murine model of airway inflammation and bronchial hyperresponsiveness. Free Radical Research, 2019, 53: 780-790. (SCI citation: 40) Gong, J.; Zhu, T.*; Hu, M.; Wu, Z.; Zhang, J.*, Different Metrics (Number, Surface Area, and Volume Concentration) of Urban Particles with Varying Sizes in Relation to Fractional Exhaled Nitric Oxide (FeNO). Journal of Thoracic Disease, 2019, 11: 1714-1726. (SCI citation: 6) Zhang, J.*; Adcock, I.; Bai, Z.; Chung, K.; Duan, X.; Fang, Z.; Gong, J.; Li, F.; Miller, R.; Qiu, X.; Rich, D.; Wang, B.; Wei, Y.; Xu, D.; Xue, T.; Zhang, Y.; Zheng, M.; Zhu, T. Health effects of air pollution: what we need to know and to do in the next decade. Journal of Thoracic Disease, 2019, 11: 1727-1730. (SCI citation: 4) Li, F.; Xu, M.; Wang, M.; Wang, L.; Wang, H.; Zhang, H.; Chen, Y.; Gong, J.; Zhang, J.; Adcock, I.; Chung, K.; Zhou, X.*, Roles of mitochondrial ROS and NLRP3 inflammasome in multiple ozone-induced lung inflammation and emphysema. Respiratory Research, 2018, 19: 230. (SCI citation: 51) Day, D.; Clyde, M.; Xiang, J.; Li, F.; Cui, X.; Mo, J.; Gong, J.; Weschler, C.; Zhang, Y.; Zhang, J.*, Age modification of ozone association with cardiovascular disease risk in adults: a potential role for soluble P-selectin and blood pressure. Journal of Thoracic Disease, 2018, 10: 4643-4652. (SCI citation: 3) Cui, X.; Li, F.; Xiang, J.; Fang, L.; Chung, M.; Day, D.; Mo, J; Weschler, C.; Gong, J.; He, L.; Zhu, D.; Lu, C.; Han, H.; Zhang, Y.; Zhang, J.*, Cardiopulmonary effects of overnight indoor air filtration in healthy non-smoking adults: A double-blind randomized crossover study. Environment International, 2018, 114: 27-36. (SCI citation: 56) Cui, X.; Gong, J.; Han, H.; He, L.; Teng, Y.; Tetley, T.; Sinharay, R.; Chung, KF.; Islam, T.; Gilliland, F.; Grady, S.; Garhick, E.; Li, Z.; Zhang, J, Relationship between free and total malondialdehyde, a well-established marker of oxidative stress, in various types of human biospecimens. Journal of Thoracic Disease, 2018, 10: 3088-3097. (SCI citation: 32) Sinharay, R.#; Gong, J.#; Barratt, B.; Ohman-Strickland, P.; Ernst, S.; Kelly, F.; Zhang, J.; Collins, P.; Cullinan, P.*; Chung, K.F., Respiratory and cardiovascular responses to walking down a traffic-polluted road compared with walking in a traffic-free area in participants aged 60 years and older with chronic lung or heart disease and age-matched healthy controls: a randomised, crossover study. Lancet, 2018, 391: 339-349. (SCI citation: 164, highly cited paper) Wheelock, K.; Zhang, J.*; McConnell, R; Tang, D.; Volk, HE.; Wang, Y.; Herbstman, JB.; Wang, S.; Phillips, DH.; Camann, D.; Gong, J.; Perera, F.*, A novel method for source-specific hemoglobin adducts of nitro-polycyclic aromatic hydrocarbons. Environmental Science: Processes & Impacts, 2018, 20: 780-789. (SCI citation: 5) Grady, S.*; Koutrakis, P.; Hart, J.; Coull, B.; Schwartz, J.; Laden, F.; Zhang, J.; Gong, J.; Moy, M.; Garshick, E., Indoor Black Carbon of Outdoor Origin and Oxidative Stress Biomarkers in Patients with Chronic Obstructive Pulmonary Disease. Environment International, 2018, 115: 188-195. (SCI citation: 15) Day, D.; Xiang, J.; Mo J.; Clyde, M.; Weschler, C.; Li F.; Gong, J.; Chung, M.; Zhang, Y.*; Zhang, J.*, Combined Use of an Electrostatic Precipitator and a High-Efficiency Particulate Air Filter in Building Ventilation Systems: Effects on Cardiorespiratory Health Indicators in Healthy Adults. Indoor Air, 2018, 28: 360-372. (SCI citation: 44)

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