谭英 - 清华大学 - 深圳国际研究生院

个人简介

2001年09月-2005年07月，华中师范大学应用化学专业本科毕业 2005年09月-2010年07月，华中师范大学/南开大学化学专业博士 2010年07月-2012年07月，清华大学博士后 2012年10月至今，清华大学深圳研究生院生命与健康学部讲师、副教授 2016年10月-2017年10月，新加坡国立大学访问学者荣誉奖项 2021年深圳市优秀教师清华大学第九届青年教师教学大赛三等奖清华大学优秀硕士学位论文指导教师

研究领域

研究方向包括肿瘤相关的化学生物学、分子生物学、细胞生物学、生物信息学，围绕药物分子（小分子、核酸、多肽）的研发及作用机制、生物传感器与分子诊断、人工智能与生物信息学等领域展开研究。

近期论文

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Bao-Cheng Wang, Tingting Fan, Fen-Ya Xiong, Peng Chen, Kai-Xin Fang, Ying Tan,* Liang-Qiu Lu,* and Wen-Jing Xiao. De Novo Construction of Chiral Aminoindolines by Cu-Catalyzed Asymmetric Cyclization and Subsequent Discovery of an Unexpected Sulfonyl Migration. Journal of the American Chemical Society, 2022, https://doi.org/ 10.1021 /jacs.2c08090. Xinyan Zhang, Zhilin Zhang, Xiaoqi Xue, Tingting Fan, Chunyan Tan, Feng Liu, Ying Tan,*and Yuyang Jiang. PROTAC Degrader of Estrogen Receptor α Targeting DNA-Binding Domain in Breast Cancer. ACS Pharmacology & Translational Science, 2022, https://doi.org/10.1021/ acsptsci.2c00109. Junyue Chen, Gerile Oudeng, Hongtao Feng, Sixi Liu, Hung-Wing Li, Yi-Ping Ho, Yan Chen,* Ying Tan,* and Mo Yang*. 2D MOF Nanosensor-Integrated Digital Droplet Microfluidic Flow Cytometry for In Situ Detection of Multiple miRNAs in Single CTC Cells. Small, 2022, 2201779. Weijie Chen, Huijuan Chen, Yurou Huang, Ying Tan,* Chunyan Tan,* Yuan Xie, and Jun Yin*. Molecular Design and Photothermal Application of Thienoisoindigo Dyes with Aggregation-Induced Emission. ACSApplied Bio Materials. 2022, 5, 3428-3437. Weijie Chen, Chen Zhang, Huijuan Chen, Kun Zang, Sheng Hua Liu, Yuan Xie, Ying Tan,*and Jun Yin*. Near-Infrared Thienoisoindigos with Aggregation-Induced Emission: Molecular Design, Optical Performance, and Bioimaging Application. Analytical Chemistry, 93, 3378-3385, 2021. (cover paper) Bifei Li, Jianhui Li, Wei Gan*, Ying Tan*, and Qunhui Yuan*. Unveiling the Molecular Dynamics in a Living Cell to the Subcellular Organelle Level Using Second-Harmonic Generation Spectroscopy and Microscopy. Analytical Chemistry, 2021, 93, 42, 14146–14152. Junyue Chen, Tian Jin, Jingfeng Li, Xinyan Zhang, Feng Liu, Chunyan Tan, and Ying Tan*. One-Pot Simultaneous Detection of Multiple DNA and MicroRNA by Integrating the Cationic-Conjugated Polymer and Nuclease-Assisted Cyclic Amplification. ACS Applied Bio Materials. 4, 820-828, 2021. Xiaoxie Ma, Chen Zhang, Lan Feng, Sheng Hua Liu, Ying Tan,* Jun Yin*. Construction and Bioimaging Application of Novel Indole Heptamethine Cyanines Containing Functionalized Tetrahydropyridine Ring. Journal of Materials Chemistry B, 8, 9906, 2020. Junyue Chen, Tingting Fan, Yan Chen, Lizhen Ye, Chen Zhang, Feng Liu, Ying Qin, Ying Tan*, Yuyang Jiang*. Zeptomolar-level one-pot simultaneous detection of multiple colorectal cancer microRNAs by cascade isothermal amplification. Biosensors and Bioelectronics. 169, 112631, 2020. Tian Jin, Jiewen Zhang, Yuanfang Zhao, Xiaoting Huang, Chunyan Tan, Shuqing Sun*, Ying Tan*. Magnetic bead-gold nanoparticle hybrids probe based on optically countable gold nanoparticles with dark-field microscope for T4 polynucleotide kinase activity assay. Biosensors and Bioelectronics. 150, 111936, 2020. Huan Shi, Tian Jin, Jiewen Zhang, Xiaoting Huang, Chunyan Tan, Yuyang Jiang,* Ying Tan*, A novel aptasensor strategy for protein detection based on G-quadruplex and exonuclease III-aided recycling amplification. Chinese Chemical Letters. 31, 155-158, 2020. Zhiqiang Xu, Xiaoting Huang, Ming-Xing Zhang, Weijie Chen, Sheng Hua Liu, Ying Tan,* and Jun Yin*, Tissue Imaging of Glutathione-Speciﬁc Naphthalimide−Cyanine Dye with Two-Photon and Near-Infrared Manners.Analytical Chemistry,91, 11343-11348, 2019. Zhiqiang Xu, Xiaoting Huang, Xie Han, Di Wu, Bibo Zhang, Ying Tan*, Meijiao Cao, Sheng Hua Liu, Jun Yin*, Juyoung Yoon*. A Visible Near-Infrared, Dual Channel Fluorescence-On Probe for Highly Selective Tracking of Mitochondrial Glutathione. Chem. 4, 1609-1628, 2018. Shuwen Liu, Naihan Xu, Chunyan Tan, Wei Fang, Ying Tan*, Yuyang Jiang. A sensitive colorimetric aptasensor based on trivalent peroxidasemimic DNAzyme and magnetic nanoparticles. Analytica Chimica Acta. 1018, 86-93, 2018. Yu Liu, Pan Wu, Jianhua Jiang, Jiatao Wu, Yan Chen, Ying Tan*, Chunyan Tan*, and Yuyang Jiang. Conjugated Polyelectrolyte Nanoparticles for Apoptotic Cell Imaging.ACS Applied Materials & Interfaces. 8 (34), 21984-21989,2016. Chen, Z.; Wu, P.; Cong, R.; Xu, N.; Tan, Y.*; Tan, C*.; Jiang, Y., Sensitive Conjugated-Polymer- Based Fluorescent ATP Probes and Their Application in Cell Imaging. ACS Applied Materials & Interfaces.8, 3567-3574, 2016.