Lin, Yao - University of Connecticut - Department of Chemistry

个人简介

George W. Beadle Postdoctoral Fellow, Argonne National Laboratory and the University of Chicago (2005-2008) Ph.D. University of Massachusetts, Amherst B.S. Fudan University, Shanghai, P.R.C.

研究领域

The Lin Group studies bio-inspired macromolecules and materials. In nature, there are many examples in which the whole is much greater than the sum of its parts. We are very curious on the mechanisms and implications of such cooperative behaviors, especially at the molecular and macromolecular levels. We believe that understanding the molecular cooperativity, and incorporating the concept into the design of synthetic and hybrid macromolecules will lead to the development of new functional materials with unprecedented collective properties. We use the techniques of polymer synthesis, macromolecular characterization, physical chemistry, molecular biology and biochemistry as tools to study and manipulate various macromolecular systems.

近期论文

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H. Lu, J. Wang, Z. Song, L. Yin, Y. Zhang, H. Tang, C. Tu, Y. Lin and J. Cheng, "Recent Advances in Amino Acid N-carboxyanhydrides and Synthetic Polypeptides: Chemistry, Self-assembly and Biological Applications," Chemical Communications 50, 139-155 (2014). J. Wang, H. Xia, Y. Zhang, H. Lu, R. Kamat, A. V. Dobrynin, J. Cheng & Y. Lin, “Nucleation-Controlled Polymerization of Nanoparticles into Supramolecular Structures,” Journal of the American Chemical Society 135, 11417–11420 (2013). [Cover Article] R. K. Kamat, W. Ma, Y. Yang, Y. Zhang, C. Wang, C. V. Kumar & Y. Lin, “Adsorption and Hydrolytic Activity of Polycatalytic Cellulase Nano-complex on Cellulose,” ACS Applied Materials & Interfaces, 5, 8486–8494 (2013). F. Liu, R. K. Kamat, I. Noshadi, D. Peck, R. Parnas, C. Qi & Y. Lin, “Depolymerization of Crystalline Cellulose Catalyzed by Acidic Ionic Liquids Grafted on Sponge-Like Nanoporous Polymers,” Chemical Communications, 49, 8456-8458 (2013). Y. Zhang, Q. Yin, H. Lu, H. Xia, Y. Lin & J. Cheng, “PEG-Polypeptide Dual Brush Block Copolymers: Synthesis and Application in Nanoparticle Surface PEGylation,” ACS Macro Letters 2, 809-813 (2013). Y. Zhang, Y. Yang, W. Ma, J. Guo, Y. Lin & C. Wang, “Uniform Magnetic Core/Shell Microspheres Functionalized with Ni2+-Iminodiacetic Acid for One Step Purification and Immoblization of His-Tagged Enzymes,” ACS Applied Materials & Interfaces 5, 2626-33 (2013). J. Wang, H. Lu, Y. Ren, Y. Zhang, M. Morton, J. Cheng & Y. Lin, “Interrupted helical structures of grafted-polypeptides in brush-like macromolecules,” Macromolecules, 44, 8699–8708 (2011). J. Wang, H. Lu, R. Kamat, S. V. Pingali, V. S. Urban, J. Cheng & Y. Lin, “Supramolecular polymerization from polypeptide-grafted comb polymers,” Journal of the American Chemical Society, 133, 12906-12909 (2011). H. Lu, J. Wang, Y. Bai, J. W. Lang. S. Liu, Y. Lin & J. Cheng, “Ionic polypeptides with unusual helical stability,” Nature Communications, 2, 206, DOI: 10.1038/ncomms1209 (2011). H. Lu, Y. Bai, J. Wang, N. P. Gabrielson, F. Wang, Y. Lin, and J. Cheng, "Ring-Opening Polymerization of γ-(4-Vinylbenzyl)-l-glutamate N-Carboxyanhydride for the Synthesis of Functional Polypeptides," Macromolecules, 44, 6237-6240 (2011). W. P. Hall, J. Modica, J. Anker, Y. Lin, M. Mrksich & R. P. Van Duyne, “A conformation- and ion-sensitive plasmonic biosensor,” Nano Letters, 11, 1098-1105 (2011). B. Luo, S. Xu, A. Luo, W. L. Wang, S. L. Wang, J. Guo, Y. Lin, D. Y. Zhao & C. C. Wang, “Mesoporous Biocompatible and acid-degradable magnetic colloidal nanocrystal clusters with sustainable stability and high hydrophobic drug loading capacity,” ACS Nano, 5, 1428-1435 (2011). Y. Zhang, H. Lu, Y. Lin & J. Cheng, "Water-Soluble Polypeptides with Elongated, Charged Side Chains Adopt Ultrastable Helical Conformations," Macromolecules, 44, 6641–6644 (2011). W. Ma, S. Xu, J. Li, J. Guo, Y. Lin & C. C. Wang, “Hydrophilic dual-responsive magnetite/PMAA core/shell microspheres with high magnetic susceptibility and pH sensitivity via distillation-precipitation polymerization," Journal of Polymer Science Part A: Polymer Chemistry, 49, 2725-2733 (2011). H. Lu, J. Wang, Y. Lin & J. Cheng, “One-pot synthesis of brush-like polymers via integrated ring-opening metathesis polymerization and polymerization of amino acids N-carboxyanhydrides,” Journal of the American Chemical Society, 131, 13582-13593 (2009). W. P. Hall, J. N. Anker, Y. Lin, J. Modica, M. Mrksich & R. P. Van Duyne, “A calcium-modulated plasmonic switch,” Journal of the American Chemical Society, 130, 5836–5837 (2008). Y. Lin, A. Böker, J. He, K. Sill, H. Xiang, C. Abetz, X. Li, J. Wang, T. Emrick, S. Long, Q. Wang, A. Balazs & T.P. Russell, “Self-directed assembly of nanoparticles/copolymer mixtures,” Nature, 434, 55-59 (2005). Y. Lin, A. Böker, H. Skaff, D. Cookson, A.D. Dinsmore, T. Emrick & T.P. Russell, “Structure and dynamics of nanoparticle assembly at liquid-liquid interfaces,” Langmuir, 21, 191-194 (2005). J.T. Russell, Y. Lin (co-first author), A. Böker, L. Su, P. Carl, H. Zettl, J. He, K. Sill, R. Tangirala, T. Emrick, K. Littrell, P. Thiyagarajan, D. Cookson, A. Fery, Q. Wang & T.P. Russell, “Self-assembly and cross-linking of bionanoparticles at liquid-liquid interfaces,” Angewandte Chemie International Edition, 44, 2420-2426 (2005). [Cover Article] H. Skaff, Y. Lin, R. Tangirala, K. Breitenkamp, A. Böker, T.P. Russell & T. Emrick, “Crosslinked Capsules of Quantum Dots by Interfacial Assembly and Ligand Crosslinking,” Advanced Materials, 17, 2082-2086 (2005).