个人简介
Ph.D. Mechanical Engineering and Materials Science, Duke University Durham, NC
M.S. Chemistry, University of Wisconsin, Milwaukee, WI
B.S. Chemistry and Philosophy, University of Wisconsin, Madison, WI
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James M. Smith, Rachna Rastogi, Ryan S. Teller, Priya Srinivasan, Pedro M. M. Mesquita, Umadevi Nagaraja, Janet M. McNicholl, R. Michael Hendry, Chuong T. Dinh, Amy Martin, Betsy C. Herold, and Patrick F. Kiser, Intravaginal ring eluting tenofovir disoproxil fumarate completely protects macaques from multiple vaginal simian-HIV challenges, PNAS, 2013, 110, no. 40, 16145–16150 (link)
Rachna Rastogi, Ryan S. Teller, Pedro M.M. Mesquita, Betsy C. Herold, Patrick F. Kiser, Osmotic pump tablets for delivery of antiretrovirals to the vaginal mucosa, Antiviral Research 2013, 100, 255–258 (link)
Justin T. Clark, Todd J. Johnson, Meredith R. Clark, Joel S. Nebeker, Judit Fabian, Anthony L. Tuitupou Satya Ponnapalli, Eric M. Smith, David R. Friend, Patrick F. Kiser, Quantitative evaluation of a hydrophilic matrix intravaginal ring for the sustained delivery of tenofovir , Journal of Controlled Release, 2012, 163, 240–248 (link)
Todd J. Johnson, Meredith R. Clark, Theodore H. Albright, Joel S. Nebeker, Anthony L. Tuitupou, Justin T. Clark, Judit Fabian, R. Tyler McCabe, Neelima Chandra, Gustavo F. Doncel, David R. Friend and Patrick F. Kiser, A 90-Day Tenofovir Reservoir Intravaginal ring for Mucosal HIV Prophylaxis, Antimicrob. Agents Chemother. 2012, 56(12):6272. (link)
Alamelu Mahalingam, Julie I. Jay, Kristofer Langheinrich, Shetha Shukair, Mike D. McRaven, Lisa C. Rohan, Betsy C. Herold, Thomas J. Hope, Patrick F. Kiser, Inhibition of the transport of HIV in vitro using a pH-responsive synthetic mucin-like polymer system, Biomaterials 2011, 32, 8343-8355 (link)
Alamelu Mahalingam, Anthony R. Geonnotti, Jan Balzarini, and Patrick F. Kiser, Activity and Safety of Synthetic Lectins Based on Benzoboroxole-Functionalized Polymers for Inhibition of HIV Entry, Mol. Pharmaceutics 2011, 8, 2465–2475 (link)
Alamelu Mahalingam, Eric Smith, Judit Fabian, Festo R. Damian, Jennifer J. Peters, Meredith R. Clark, David R. Friend, David F. Katz, Patrick F. Kiser, Design of a Semisolid Vaginal Microbicide Gel by Relating Composition to Properties and Performance, Pharm Res 2010, 27:2478–2491 (link)
Julie I. Jay, Bonnie E. Lai, David G. Myszka, Alamelu Mahalingam, Kris Langheinrich, David F. Katz, and Patrick F. Kiser, Multivalent Benzoboroxole Functionalized Polymers as gp120 Glycan Targeted Microbicide Entry Inhibitors, Mol Pharm 2010, 7(1), 116–129 (link)
Julie I. Jay, Shetha Shukair, Kristofer Langheinrich, Melissa C. Hanson, Gianguido C. Cianci, Todd J. Johnson, Meredith R. Clark, Thomas J. Hope, Patrick F. Kiser, Modulation of Viscoelasticity and HIV Transport as a Function of pH in a Reversibly Crosslinked Hydrogel, Adv. Funct. Mater. 2009, 19, 2969–2977 (link)
Meredith C. Roberts, Alamelu Mahalingam, Melissa C. Hanson, and Patrick F. Kiser, Chemorheology of Phenylboronate-Salicylhydroxamate Cross-Linked Hydrogel Networks with a Sulfonated Polymer Backbone, Macromolecules 2008, 41, 8832-8840 (link)
Meredith C. Roberts, Melissa C. Hanson, Archna P. Massey, Elliott A. Karren, and Patrick F. Kiser, Dynamically Restructuring Hydrogel Networks Formed with Reversible Covalent Crosslinks, Adv. Mater. 2007, 19, 2503–2507 (link)
Kenneth D. Eichenbaum, Allen A. Thomas, Gary M. Eichenbaum, Brian R. Gibney, David Needham, and Patrick F. Kiser, Oligo-R-hydroxy Ester Cross-Linkers: Impact of Cross-Linker Structure on Biodegradable Hydrogel Networks, Macromolecules 2005, 38, 10757-10762 (link)