个人简介

PhD, University of Toronto, Toronto, Canada, 1998 (Physical Chemistry).

研究领域

Photodynamic therapy; enhanced spectroscopy; photon upconversion; sensing; nanomaterials

Nanoscience is at the unexplored frontiers of science and engineering, and it offers one of the most exciting opportunities for innovation in technology. One of the hopes for nanoscience and technology is that the combination of a number of areas - from physics and chemistry to material science and biology - will create a new area and lead to major advances both in understanding of science and in their applications in technology. Key to this new era is research across many disciplinary interfaces. As illustrated in the following diagram, the central theme of this research program is metal-enhanced spectroscopies and their applications, typically bio-related, based on various types of nanomaterials.

近期论文

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C. Lee, P. Zhang*. Highly stable gelatin layer-protected gold nanoparticles as surface-enhanced Raman scattering substrates. J. Nanoscience and Nanotechnology. 14, 4325-30 (2014). Y. Zhou, P. Zhang*. Simultaneous SERS and surface-enhanced fluorescence from dye-embedded metal core-shell nanoparticles. PhysChemChemPhys. 16 (19), 8791 - 8794 (2014). P. Wang, P. Joshi, A. Alazemi, P. Zhang*. Upconversion nanoparticle-based ligase-assisted method for specific and sensitive detection of T790M mutation in epidermal growth factor receptor. Biosens. Bioelectron. 62, 120-126 (2014). B. Hu, X. Cao, K. Nahan, J. Caruso, H. Tang,* P. Zhang*. Surface Plasmon-Photosensitizer Resonance Coupling: An Enhanced Singlet Oxygen Production Platform for Broad-Spectrum Photodynamic Inactivation of Bacteria. J. Mater. Chem. B. 2, 7073-7081 (2014). P. Joshi, Y. Zhou, Tevhide Ozkaya Ahmadov, P. Zhang*. Quantitative SERS-based detection using Ag-Fe3O4 nanocomposites with internal reference. J. Mater. Chem. C. 2, 9964-9968 (2014). P. Wang, P. Zhang*. Upconversion luminescence resonance energy transfer-based ligase-assisted method for specific and sensitive detection of V600E mutation in BRAF gene. RSC Advances. 4, 56235-56240 (2014). Xinjun Yu, Xian Cao, Xiaoping Chen, Neil Ayres,* P. Zhang*. Triplet-Triplet Annihilation Upconversion from Rationally Designed Polymeric Emitters with Tunable Inter-Chromophore Distances. Chem. Comm. 51, 588 (2015). C. Lee, M. Gaston, A. Weiss, P. Zhang*. Colorimetric viral detection based on sialic acid stabilized gold nanoparticles. Biosens. Bioelectron. 42, 236-241 (2013). B. Hu, X. Cao, P. Zhang*. Selective Colorimetric Detection of Glutathione Based on Quasi-Stable Gold Nanoparticles Assembly. New J. Chem. 37, 3853-3856 (2013). B. Hu, X. Cao, P. Zhang*. Dual control of interparticle forces in gold nanoparticles assembly. ChemPlusChem.78(6), 506-514 (2013). doi:10.1002/cplu.201300091 Y. Zhou, C. Lee, J. Zhang, P. Zhang*. Engineering versatile SERS-active nanoparticles by embedding reporters between Au-core/Ag-shell through layer-by-layer deposited polyelectrolytes. J. Mater. Chem. C. 1(23), 3695 – 3699 (2013). DOI: 10.1039/C3TC30561A. C. Lee, P. Zhang*. Facile synthesis of gelatin-protected silver nanoparticles for SERS applications. J. Raman Spectroscopy. 44, 823-826 (2013). DOI: 10.1002/jrs.4304. X. Cao, B. Hu, P. Zhang*. High Upconversion Efficiency from Hetero Triplet-Triplet Annihilation in Multi-Acceptor Systems. J. Phys. Chem. Letters. 4, 2334-2338 (2013). DOI: 10.1021/jz041213w. P. Wang, T. Ozkaya Ahmadov, C. Lee, P. Zhang*. Ligase-assisted signal-amplifiable DNA detection using upconversion nanoparticles. RSC Advances. 3(37), 16326-16329 (2013). DOI: 10.1039/c3ra42421a. Effect of a second metal (Y, K, Ca, Mn or Cu) addition on the carbon dioxide reforming of methane over nanostructured palladium catalysts.C. Shi, P. Zhang. Appl. Catal. B: Environmental. V115-116, 190 (2012). N. Liu, M. Gong, P. Zhang, L. Li, W. Li, R. Lee. Silver-embedded zeolite crystals as substrates for surface-enhanced Raman scattering. J. Mater. Sci. 46, 3162-8 (2011). W. Li, X. Miao, T. S. Luk, P. Zhang. Enormous average enhancement factors from SERS-tags of TiO2-core mixed metal-shell nanoparticles. J. Phys. Chem. C.115, 3318 (2011). W. Li, J. Zhang, Y. Zhou, P. Zhang. Highly enhanced fluorescence of fluorophores inside a metallic nanocavity. Chem. Comm. 47(20), 5834-6 (2011). M. Kumar, P. Zhang. Highly Sensitive and Selective Label-Free Optical Detection of Mercuric Ions Using Photon Upconverting Nanoparticles. Biosens. Bioelectron. 25, 2431 (2010). H. Tang, P. Zhang, T.L. Kieft, S.J. Ryan, S.M. Baker, W.P. Wiesmann, S. Rogelj. Antibacterial action of a novel functionalized chitosan-arginine against gram-negative bacteria. Acta Biomaterialia. 6(7), 2562 (2010).