研究领域
Kozlowski's lab at DePaul University is focused on Traumatic Brain Injury (TBI) in a rodent model. They have examined numerous approaches aimed at repairing the injured brain following TBI including: gene therapy, bone marrow stem cell transplants, endogenous neurogenesis, and physical rehabilitation. Their current emphasis is on using a model of repeat concussions to understand how they are linked to neurodegenerative disease as well as whether APOE4 is a genetic risk factor for brain trauma related neurodegenerative disease. They utilize steretotaxic surgery, quantitative anatomical analysis, and sophisticated behavioral techniques in our studies. Their overall goal is to understand how the brain tries to repair itself, and how external therapies can help the brain do so.
近期论文
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Adkins, D.A., Ferguson, L., Lance, S., McDonough, K., Pevtsov, A., Jones, T.A. & Kozlowski, D.A. (2015) Combining motor rehabilitation tasks enhances behavioral recovery following experimental traumatic brain injury in rats. Neurorehabilitation and Neural Repair. 29(10): 989-1000.?
Kozlowski, D.A., Leasure, J.L., Schallert, T. (2013) The Control of Movement Following Traumatic Brain Injury. Comprehensive Physiology. 3(1) 121-139. doi: 10.1002/cphy.c110005
Kozlowski, D.A. & Jones, T.A. (2012) Plasticity and Recovery of the Injured Brain. In. (Morganti-Kossman, C., Raghupathi, R., & Maas, A. Editors) “Traumatic brain and spinal cord injury: Challenges and developments in research: Translating Research into Clinical Practice”. Cambridge University Press.
Jones, T.A., *Liput, D.J., Maresh, E., Donlan, N. Parikh, T., Marlowe, D., Jones, T.A. & Kozlowski, D.A. (2012) Use-dependent dendritic regrowth is limited following unilateral controlled cortical impact to the forelimb sensorimotor cortex. Journal of Neurotrauma 29(7):1455-1468. Article chosen to highlight for cover photo.*both authors contributed equally to this manuscript
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