欧阳证 - 清华大学 - 精密仪器系

个人简介

教育背景 1989/09-1993/07 清华大学，信息科学技术学院自动化系，工学学士 1993/09-1995/07 清华大学，信息科学技术学院自动化系，工学硕士 1995/09-1997/05 西弗吉尼亚大学，物理化学系，理学硕士 1997/08-2002/03 普渡大学，分析化学系，哲学博士 2002/03-2002/12 普渡大学，分析化学系，博士后工作履历 2003-2006 普渡大学化学系，助理研究员/副研究员 2007-2015 普渡大学生物医学工程系，助理教授/副教授/教授 2015-至今清华大学精密仪器系，教授 2016-至今清华大学精密仪器系，系主任

研究领域

质谱分析系统及方法主要研究质谱仪分析器基本原理，采样离子化方法，数据分析；研制气态离子化学科学研究仪器，离子阱质谱仪小型化，发展生物医学分析方法

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

X. Zhou, X. Liu and Z. Ouyang; "Statistical Algorithm Enables Rapid Computation of Space Charge Effect and Spectral Correction in a Miniature Ion Trap Mass Spectrometer", Journal of the American Society for Mass Spectrometry, 2020, 31, 429-433, DOI: 10.1021/jasms.9b0011 H.-F. Li, W. Cao, X. Ma, X. Xie, Y. Xia and Z. Ouyang; "Visible-Light-Driven [2 + 2] Photocycloadditions between Benzophenone and C=C Bonds in Unsaturated Lipids", Journal of the American Chemical Society, 2020, 142, 3499-3505, DOI: 10.1021/jacs.9b12120 M. Kang, W. Zhang, L. Dong, X. Ren, Y. Zhu, Z. Wang, L. Liang, J. Xue, Y. Zhang, W. Zhang and Z. Ouyang; "On-site testing of multiple drugs of abuse in urine by a miniature dual-LIT mass spectrometer", Analytica Chimica Acta, 2020, 1101, 74-80, DOI: https://doi.org/10.1016/j.aca.2019.12.028 X. Guo, H. Bai, X. Ma, J. Li, Y. Ren, Z. Ouyang and Q. Ma; "Online coupling of an electrochemically fabricated solid-phase microextraction probe and a miniature mass spectrometer for enrichment and analysis of chemical contaminants in infant drinks", Analytica Chimica Acta, 2020, 1098, 66-74, DOI: https://doi.org/10.1016/j.aca.2019.11.021 J. Fan, P. Lian, M. Li, X. Liu, X. Zhou and Z. Ouyang; "Ion Mobility Separation Using a Dual-LIT Miniature Mass Spectrometer", Analytical Chemistry, 2020, 92, 2573-2579, DOI: 10.1021/acs.analchem.9b0427 W. Cao, S. Cheng, J. Yang, J. Feng, W. Zhang, Z. Li, Q. Chen, Y. Xia, Z. Ouyang and X. Ma; "Large-scale lipid analysis with C=C location and sn-position isomer resolving power", Nature Communications, 2020, 11, 375, DOI: 10.1038/s41467-019-14180-4 F. Pu, S. Pandey, L. R. Bushman, P. L. Anderson, Z. Ouyang and R. G. Cooks; "Direct quantitation of tenofovir diphosphate in human blood with mass spectrometry for adherence monitoring", Analytical and Bioanalytical Chemistry, 2020, 412, 1243-1249, DOI: 10.1007/s00216-019-02304-0 X. Zhao, W. Zhang, D. Zhang, X. Liu, W. Cao, Q. Chen, Z. Ouyang and Y. Xia; "A lipidomic workflow capable of resolving sn- and CC location isomers of phosphatidylcholines", Chemical Science, 2019, 10, 10740-10748, DOI: 10.1039/C9SC03521D W. Zhang, D. Zhang, Q. Chen, J. Wu, Z. Ouyang and Y. Xia; "Online photochemical derivatization enables comprehensive mass spectrometric analysis of unsaturated phospholipid isomers", Nature Communications, 2019, 10, 79, DOI: 10.1038/s41467-018-07963-8 W. Zhang, Y. Ren, Z. Lin and Z. Ouyang; "High-Precision Quantitation of Biofluid Samples Using Direct Mass Spectrometry Analysis", Analytical Chemistry, 2019, 91, 6986-6990, DOI: 10.1021/acs.analchem.9b01694 W. Zhang, S. Chiang, Z. Li, Q. Chen, Y. Xia and Z. Ouyang; "A Polymer Coating Transfer Enrichment Method for Direct Mass Spectrometry Analysis of Lipids in Biofluid Samples", Angewandte Chemie International Edition, 2019, 58, 6064-6069, DOI: 10.1002/anie.201900011 J. Yang, W. Zhang, H. Zhang, M. Zhong, W. Cao, Z. Li, X. Huang, Z. Nie, J. Liu, P. Li, X. Ma and Z. Ouyang; "Polydopamine-Modified Substrates for High-Sensitivity Laser Desorption Ionization Mass Spectrometry Imaging", ACS Applied Materials & Interfaces, 2019, 11, 46140-46148, DOI: 10.1021/acsami.9b16260 Y. Su, X. Ma, J. Page, R. Shi, Y. Xia and Z. Ouyang; "Mapping lipid C=C location isomers in organ tissues by coupling photochemical derivatization and rapid extractive mass spectrometry", International Journal of Mass Spectrometry, 2019, 445, 116206, DOI: https://doi.org/10.1016/j.ijms.2019.116206 F. Pu, S. Chiang, W. Zhang and Z. Ouyang; "Direct sampling mass spectrometry for clinical analysis", Analyst, 2019, 144, 1034-1051, DOI: 10.1039/c8an01722k F. Pu, C. M. Alfaro, V. Pirro, Z. Xie, Z. Ouyang and R. G. Cooks; "Rapid determination of isocitrate dehydrogenase mutation status of human gliomas by extraction nanoelectrospray using a miniature mass spectrometer", Analytical and bioanalytical chemistry, 2019, 411, 1503-1508, DOI: 10.1007/s00216-019-01632-5 X. Liu, X. Wang, J. Bu, X. Zhou and Z. Ouyang; "Tandem Analysis by a Dual-Trap Miniature Mass Spectrometer", Analytical Chemistry, 2019, 91, 1391-1398, DOI: 10.1021/acs.analchem.8b03958 M. Li, X. Liu, X. Zhou and Z. Ouyang; "Ion-Neutral Collision Effects on Ion Trapping and Pseudopotential Depth in Ion Trap Mass Spectrometry", Journal of the American Society for Mass Spectrometry, 2019, 30, 2750-2755, DOI: 10.1021/jasms.8b0629 L. Chong, R. Tian, R. Shi, Z. Ouyang and Y. Xia; "Coupling the Paternò-Büchi (PB) Reaction With Mass Spectrometry to Study Unsaturated Fatty Acids in Mouse Model of Multiple Sclerosis", Frontiers in Chemistry, 2019, 7, DOI: 10.3389/fchem.2019.00807 S. Cheng, W. Cao, X. Zhao, N. Li, Z. Ouyang, Q. Ma and X. Ma; "Fast screening of prohibited chemicals in plastic toys using ambient ionization mass spectrometry", International Journal of Mass Spectrometry, 2019, 444, 116176, DOI: https://doi.org/10.1016/j.ijms.2019.116176 H. M. Brown, F. Pu, M. Dey, J. Miller, M. V. Shah, S. A. Shapiro, Z. Ouyang, A. A. Cohen-Gadol and R. G. Cooks; "Intraoperative detection of isocitrate dehydrogenase mutations in human gliomas using a miniature mass spectrometer", Analytical and Bioanalytical Chemistry, 2019, 411, 7929-7933, DOI: 10.1007/s00216-019-02198-y R. Zou, W. Cao, L. Chong, W. Hua, H. Xu, Y. Mao, J. Page, R. Shi, Y. Xia, T. Y. Hu, W. Zhang and Z. Ouyang; "Point-of-Care Tissue Analysis Using Miniature Mass Spectrometer", Analytical Chemistry, 2019, 91, 1157-1163, DOI: 10.1021/acs.analchem.8b04935