当前位置: X-MOL首页全球导师 国内导师 › 王银银

个人简介

关注学科前沿, 科研模式教学,助力未来卓越医师科学家的科研思维 王银银,西北农林科技大学硕士,现任清华大学医学院基础医学系高级工程师。主要从事基础医学实验教学工作,课程包括《医学免疫学》、《医学遗传学》、《基础医学综合实验》、《神奇的免疫学》、《科研探究-人体免疫防御系统及现代免疫技术》等。以培养“卓越医师科学家”为课程培养目标,关注免疫学,遗传学,分子与细胞生物学等多个基础医学学科前沿,将课程内容形成一个整体,开展以小课题为主的科研模式实验教学,培养学生科研思维及创新能力。主编或参编国家级实验教材4本,承担课程获得北京市优质课程,清华大学精品课、挑战性课程等多项奖项。 履历 2003年11月-至今 清华大学医学院,工程师 2001年7月-2003年10月清华大学生物科学与技术系,初级工程师 1998年9月-2001年7月 西北农林科技大学农学系,硕士

研究领域

肿瘤基因,信号转导,蛋白降解,蛋白修饰,转录调控 肿瘤相关基因的功能与机制研究

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Xuanzi Fan#, Juan Zhao#, Fangli Ren,Yinyin Wang, Yarui Feng, Lidan Ding, Linpeng Zhao, Jun Li, Jianquan Ni, Baoqing Jia, Zhijie Chang*. Dimerization of p15RS mediated by a leucine-zipper-like motif is critical for its inhibitory role on Wnt signaling. J Biol Chem, Accepted, 2018. Yanquan Zhang, Shiyan Wang, Wei Kang, Chunxiao Liu, Yujuan Dong, Fangli Ren,Yinyin Wang, Jinglin Zhang, Guoping Wang, Ka-Fai To, Xueji Zhang, Joseph Sung, and Zhijie Chang*, Jun Yu*. CREPT facilitates colorectal cancer growth through inducing Wnt/b-catenin pathway by enhancing p300-mediated b-catenin acetylation. Oncogene, Accepted, 2018 Liang, Jiao(#); Li, Jun; Fu, Yanxia; Ren, Fangli; Xu, Jiake; Zhou, Mengyu; Li, Peiyu(*); Feng, Haotian(*);Wang, Yinyin(*),GdX/UBL4A null mice exhibit mild kyphosis and scoliosis accompanied by dysregulation of osteoblastogenesis and chondrogenesis.Cell Biochem Funct, 2018.2.20, 36: 1~8 (通讯作者) Shang, Y.(#); He, J.;Wang, Y.; Feng, Q.; Zhang, Y.; Guo, J.; Li, J.; Li, S.; Wang, Y.; Yan, G.; Ren, F.; Shi, Y.; Xu, J.; Zeps, N.; Zhai, Y.; He, D.; Chang, Z.(*),CHIP/Stub1 regulates the Warburg effect by promoting degradation of PKM2 in ovarian carcinoma, ONCOGENE, 2017.7.20, 36(29): 4191~4200 Liang, Jiao(#); Qiu, Ying;Wang, Yinyin; Ren, Fangli; Chang, Zhijie(*),CREPT expression correlates with esophageal squamous cell carcinoma histological grade and clinical outcome, INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2017, 10(2): 2030~2035 Kuang, Yan-Shen(#); Wang, Yi(#); Ding, Li-Dan; Yang, Liu; Wang, Ying; Liu, Si-Han; Zhu, Bing-Tao; Wang, XuNing; Liu, Hong-Yi; Li, Jun; Chang, Zhi-Jie;Wang, Yin-Yin; Jia, Bao-Qing(*),Overexpression of CREPT confers colorectal cancer sensitivity to fluorouracil.World J Gastroenterol, 2018.1.28, 24(4): 475~483 Li, Chunlei(#); Fu, Yanxia;Wang, Yinyin; Kong, Yanhua; Li, Mengdi; Ma, Danhui; Zhai, Wanli; Wang, Hao; Lin, Yuting; Liu, Sihan; Ren, Fangli; Li, Jun; Wang, Yi(*),Mesenchymal stromal cells ameliorate acute allergic rhinitis in rats., Cell Biochem Funct, 2017.10, 35(7): 420~425 Yang, Shigao(#);Wang, Yinyin(#); Mei, Kunrong; Zhang, Sen; Sun, Xiaojun; Ren, Fangli; Liu, Sihan; Yang, Zi; Wang, Xinquan; Qin, Zhihai; Chang, Zhijie(*),Tumor necrosis factor receptor 2 (TNFR2).interleukin-17 receptor D (IL17RD) heteromerization reveals a novel mechanism for NF-kappaB activation., J Biol Chem, 2015.1.9, 290(2): 861~871 (共同第一作者) Liu, Chunxiao(#); Zhang, Yanquan; Li, Jun;Wang, Yinyin; Ren, Fangli; Zhou, Yifan; Wu, Yinyuan; Feng, Yarui; Zhou, Yu; Su, Fuqin; Jia, Baoqing; Wang, Dong; Chang, Zhijie(*),p15RS/RPRD1A (p15INK4b-related sequence/regulation of nuclear pre-mRNA domain-containing protein 1A) interacts with HDAC2 in inhibition of the Wnt/beta-catenin signaling pathway.J Biol Chem, 2015.4.10, 290(15): 9701~9713 Ren, Fangli(#); Geng, Yongtao; Minami, Takayuki; Qiu, Ying; Feng, Yarui; Liu, Chunxiao; Zhao, Juan;Wang, Yinyin; Fan, Xuanzi; Wang, Yangmeng; Li, Mengdi; Li, Jun(*); Chang, Zhijie(*),Nuclear termination of STAT3 signaling through SIPAR (STAT3-Interacting Protein As a Repressor)-dependent recruitment of T cell tyrosine phosphatase TC-PTP.FEBS Lett, 2015.7.8, 589(15): 1890~1896 Xiao, Kang(#);Wang, Yinyin; Chang, Zhijie; Lao, Yuanzhi(*); Chang, Donald C(*),p32, a novel binding partner of Mcl-1, positively regulates mitochondrial Ca(2+) uptake and apoptosis., Biochem Biophys Res Commun, 2014.8.22, 451(2): 322~328 Ren, Fangli(#); Wang, Ruoke; Zhang, Yanquan; Liu, Chunxiao;Wang, Yinyin; Hu, Jim; Zhang, Linqi; Chang, Zhijie(*),Characterization of a monoclonal antibody against CREPT, a novel protein highly expressed in tumors., Monoclon Antib Immunodiagn Immunother, 2014.12.01, 33(6): 401~408

推荐链接
down
wechat
bug