邢东明 - 清华大学 - 生命科学学院

个人简介

邢东明，籍贯山东，中国协和医科大学医学硕士、生物医学工程博士，清华大学博士后（新药创制方向），美国约翰霍普金斯大学高级访问学者。清华大学生命科学院药物药理研究室主任。青岛大学青岛肿瘤研究院执行理事、执行院长，青岛大学肿瘤医工研协同创新中心主任。特聘教授、博导。两项国家重大新药创制首席专家，全球首个有效部位群新药（获国家一类新药证书）第一发明人，累计获得新药临床批件6项、新药证书3项。临床医学、生物医学工程的医工交叉教育、科研的履历，具有从临床问题提炼科学问题、从理论研究到技术实现的创新及组织能力，具有从新药成药关键技术到临床研究、工业化GMP生产全过程经验。与近十家上市公司建立了成功的创新研究与转化合作，被《人民日报》等知名媒体进行报道。

研究领域

有效部位天然药物的关键技术研究与新药创制；中药以及天然产物新功能因子研究新型肿瘤靶向药物的关键技术研究与创制智能医械、再生材料、诊断试剂的研究与创制

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

YugangWang, Yusong R Guo, Ke Liu, Zheng Yin, Rui Liu, Yan Xia, Lin Tan, Peiying Yang,Jong-Ho Lee, Xin-Jian Li, David Hawke, Yanhua Zheng, Xu Qian, Jianxin Lyu, JieHe, Dongming Xing*, Yizhi Jane Tao, Zhimin Lu. KAT2A coupled with theα-KGDH complex acts as a histone H3 succinyltransferase. Nature. 2017,552(7684):273-277. Zhang R*, Song Z, Wang X, XueJ, Xing D* One-step modification to identify dual-inhibitors targetingboth pancreatic triglyceride lipase and Niemann-Pick C1-like 1. Eur J MedChem. 2021 Apr 15;216:113358. Tingting Zhang, NannanLu, Chao Wang, Renshuai Zhang, Wujun Chen, Zhiquan Zhang, Dongming Xing*. Biomimetic cascade nanoreactor with triple-enzymemimetic activities for colorimetric detection of acid phosphatase. Chemical Engineering Journal. 2022, 437, 135267. DOI:10.1016/j.cej.2022.135267. Zhang T, Liu Y, Pi J, LuN, Zhang R, Chen W, Zhang Z, Xing D*.A novel artificial peroxisome candidate based on nanozyme with excellentcatalytic performance for biosensing. Biosens Bioelectron. 2022, 196:113686. Binghuan Huang, BingLiang, Renshuai Zhang, DongmingXing*.Molecule fluorescent probes for adenosine triphosphate imaging in cancer cellsand in vivo. Coordination Chemistry Reviews. Volume 452, 1 February 2022. Xing Jiyao, Liu Ning, XuNanan, Chen Wujun, Xing Dongming*. Engineering complex anisotropic scaffolds beyond simply uniaxialalignment for tissue engineering. Advanced Functional Materials. 2021.DOI: 10.1002/adfm.202110676 JieWang, Qian Li, Jiao Xue, Wujun Chen, Renshuai Zhang, Dongming Xing*. Shape matters: Morphologicallybiomimetic particles for improved drug delivery. Chemical Engineering Journal. 2021, 410, 127849. DOI: 10.1016/j.cej.2020.127849. Wu Y, Cui S, Li Q, ZhangR, Song Z, Gao Y, Chen W, Xing D*.Recent advances in duplex-specific nuclease-based signal amplificationstrategies for microRNA detection. Biosens Bioelectron. 2020, 165:112449.