傅肃能 - 生物岛实验室 - 神经代谢与再生研究中心

个人简介

傅肃能博士，男，1998年本科毕业于复旦大学遗传系，2004年博士毕业于美国佐治亚大学植物系。2004-2013年在美国哈佛大学公共卫生学院遗传与疾病系担任博士后、助理研究员；2013-2020年在清华大学生命学院担任研究员、博导；2020年全职加入生物岛实验室担任研究员。其曾入选国家重大青年人才项目，并获得过Naomi Berry Award in Diabetes Research，2008 NIH Roadmap Fellowship。

研究领域

综合运用生化、细胞和系统生物学的手段从事代谢及代谢相关疾病的研究和新药的筛选。主要相关联的研究领域： 1.代谢相关的细胞器功能调控，特别是内质网和线粒体功能调控机理 2.蛋白质翻译对代谢及细胞器功能的调控 3.系统生物学水平研究代谢的综合调控

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Fangfang Sun, Yilie Liao, Xingfan Qu,Xia Xiao, Shaocong Hou, Zheqin Chen, Haipeng Huang, Pingping Li, Suneng Fu. Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity.Cell Rep. 2020, 30(6):1835-1847. Xiaojie Bai, Suneng Fu*. GetArtemisininsByAnymeans (GABA): artemisinins path to conquer diabetes go through GABA receptors. Science Bulletin, 2017, 62, 383-385 Suneng Fu*. From glucose sensing to a unified model of AMPK and mTOR regulation. Science Bulletin, 2017, 62, 1233-1234. 黄海鹏, 傅肃能*. 人体与哺乳动物的生物钟同步机制及疾病[J]. 科学通报, 2017(25):15-24. Yi Yao, Shouhong Jin, Haizhou Long, Yingting Yu, Zhenming Zhang, Ge Cheng, Chengwei Xu, Yan Ding, Qian Guan, Ning Li, Suneng Fu, Xiang-Jun Chen, Yong-Bin Yan, Hanshuo Zhang, Pei Tong,Yue Tan, Yang Yu, Shushu Fu, Juan Li, Guang-Jun He, Qiong Wu. RNAe: an effective method for S. Fu - page 2 targeted protein translation enhancement by artificial non-coding RNA with SINEB2 repeat. Nucleic Acids Res. 2015, 43:e58. Ling Yang, Ediz S. Calay, Jason Fan, Alessandro Arduini, Ryan C. Kunz, Steven P. Gygi, Abdullah Yalcin, Suneng Fu, Gökhan S. Hotamisligil*. S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction. Science. 2015, 349, 500-6. Suneng Fu#, Abdullah Yalcin#, Grace Y. Lee#, Ping Li, Jason Fan, Ana Paula Arruda, Benedicte M. Pers, Mustafa Yilmaz, Kosei Eguchi, Gökhan S. Hotamisligil*，Phenotypic assays identify a small molecule modulator of the unfolded protein response with anti-diabetic activity. Sci. Transl. Med.2015, 7, 292-98. Suneng Fu, Steve M. Watkins*, Gökhan S. Hotamisligil*，The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signaling. Cell Metab. 2012, 15, 623-34. Suneng Fu, Yang, L., Li, P., Hofmann, O., Dicker, L., Hide, W., Lin, X., Watkins, S.M., Ivanov, A.R., Hotamisligil, G.S. (2011) Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity. Nature. 473, 528-31. Ling Yang, Ping Li, Suneng Fu, Ediz S. Calay, Gokhan S. Hotamisligil. Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. Cell Metab. 2010, 11, 467-78. Matthew R. Jones, Lee J. Quinton, Matthew T. Blahna, Joel R. Neilson, Suneng Fu, Alexander R. Ivanov, Dieter A. Wolf & Joseph P. Mizgerd. Zcchc11-dependent uridylation of microRNA directs cytokine expression. Nat Cell Biol. 2009, 11(9):1157-63. Suneng Fu, Peter Rogowsky, Lutz Nover, Michael J. Scanlon. The maize heat shock factor-binding protein paralogs EMP2 and HSBP2 interact non-redundantly with specific heat shock factors. Planta. 2006, 224, 42-52. Suneng Fu, Michael J. Scanlon. Clonal mosaic analysis of EMPTY PERICARP2 reveals nonredundant functions of the duplicated HEAT SHOCK FACTOR BINDING PROTEINs during maize shoot development. Genetics. 2004, 167, 1381-94. Suneng Fu, Robert Meeley, Michael J. Scanlon. Empty pericarp2 encodes a negative regulator of the heat shock response and is required for maize embryogenesis. Plant Cell. 2002, 14, 3119-32.