姚睿 - 清华大学 - 机械工程系

个人简介

教育背景 2005/09-2010/07,清华大学，博士 2008/08-2009/03,麻省理工学院，公派联培博士生 2001/09-2005/07,华中科技大学，学士工作履历 2013/06-2017/04, 清华大学机械工程系，助理研究员 2017/04-2017/08, 清华大学机械工程系，助理教授 2017/08至今, 清华大学机械工程系，副教授

研究领域

具有多学科交叉领域的训练和研究背景，研究兴趣集中在：开发和利用生物三维打印、细胞微球、微纳制造、组织芯片和材料支架制造等生物制造工程的技术构建基于活细胞、生物材料和特定因子的仿生的体外三维类组织模型，用于组织的体内再生修复、病理/药理模型构建、干细胞生物发育以及药物检测和筛选等方面的研究。

近期论文

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Yang Li, Ling Li, Zhi-Nan Chen, Ge Gao, Rui Yao*, Wei Sun*. Engineering-derived approaches for iPSC preparation, expansion, differentiation and applications. Biofabrication. 2017, 9(3):032001 Long Zhao, Karen Chang Yan, Rui Yao, Feng Lin, Wei Sun. Modeling on Micro-droplet Formation for Cell Printing Based on Alternating Viscous-Inertial Force Jetting. Journal of Manufacturing Science and Engineering. 2017, 139(1): 011005-011014 Rui Yao, Gang Xu, Shuang-Shuang Mao, Hua-Yu Yang, Xin-Ting Sang, Wei Sun, Yi-Lei Mao. Three-dimensional printing: review of application in medicine and hepatic surgery. Cancer Biol Med. 2016; 13(4): 443–451. Liliang Ouyang, Rui Yao*, Yu Zhao, Sun Wei. Effect of bioink properties on printability and cell viability for 3D bioplotting of embryonic stem cells. Biofabrication. 2016 Sep 16;8(3):035020. Yu Zhao, Yang Li, Shuangshuang Mao, Wei Sun, Rui Yao*. The influence of printing parameters on cell survival rate and printability in microextrusion-based 3D cell printing technology. Biofabrication. 2015, 7(4):045002(Correspondence author, Featured as Key Scientific Article by Global Medical Discovery) Liliang Ouyang+, Rui Yao+, Shuangshuang Mao, Xi Chen,Jie Na, Wei Sun*. Three-dimensional bioprinting of embryonic stem cells directs highly uniform embryoid body formation. Biofabrication. 2015;7(4):044101. (Co-first author, Special issue, Featured article) Liliang Ouyang+; Rui yao+; Xi Chen; Jie Na; Wei Sun*. 3D printing of HEK 293FT cell-laden hydrogel into macroporous constructs with high cell viability and normal biological functions. Biofabrication. Biofabrication, 2015, 7(1): 015010. (Co-first author) Long Zhao, Karen Chang Yan, Rui Yao, Feng Lin, Wei Sun. Alternating Force Based Drop-on-demand Micro-droplet Formation and 3D Deposition. Journal of Manufacturing Science and Engineering, 2015, 137(1): 031009-031018 Rui Yao, Jingyu Wang, Xiaokang Li, Jung Da, Hao Qi, Keh Kooi Kee, Yanan Du*. Hepatic Differentiation of Human Embryonic Stem Cells as Microscaled Multilayered Colonies Leading to Enhanced Homogeneity and Maturation. Small. 2014; 10(21): 4311-23.(Frontispiece Report) Yu Zhao+, Rui Yao+, Liliang Ouyang, Hongxu Ding, Ting Zhang, Kaitai Zhang, Shujun Cheng, Wei Sun*. 3D printing of Hela cells for cervical tumor model in vitro. Biofabrication. 2014; 6(3): 035001 (Co-first author, Featured Article) Chengyang Wang, Zhenyu Tang, Yu Zhao, Rui Yao, Lingsong Li, Wei Sun*. Three-dimensional in vitro Cancer Models: A Short Review. Biofabrication, 2014; 6(2): 022001. Rui Yao*, Yanan Du, Renji Zhang, Feng Lin, Jie Luan. A biomimetic physiological model for human adipose tissue by adipocytes and endothelial cell cocultures with spatially controlled distribution. Biomedical Materials. 2013. 8(4): 045005. (Correspondence author, Featured Article, 2013 Highlight, 2013 Editor’s Pick) Rui Yao*, Renji Zhang, Feng Lin, Jie Luan. Biomimetic injectable HUVEC-adipocytes/collagen/ alginate microsphere co-cultures for adipose tissue engineering. Biotechnology and Bioengineering. 2013. 110(5): 1430-1443 (Correspondence author, Spotlight Article) Renji Zhang, Rui Yao, Ting Zhang, Lei Zhang, Feng Lin, Wei Sun. Exploration of industrialization of 3D printing technology in Beijing. New Industry of Materials. 2013. 8: 25-30 Rui Yao*, Renji Zhang, Lin Feng, Jie Luan. Injectable cell/hydrogel microspheres induce the formation of fat lobule-like microtissues and vascularized adipose tissue regeneration. Biofabrication, 4(4): 045003, 2012 Rui Yao*, Renji Zhang, Jie Luan, Lin Feng. Alginate and alginate/gelatin microspheres for human adipose-derived stem cell encapsulation and differentiation. Biofabrication, 4(2): 025007, 2012 Rui Yao, Renji Zhang, Xiaohong Wang*. Cell Microencapsulation by Noncontact High Potentiometric Dispersion Technology. Chinese Journal of Mechanical Engineering, 2010; 46(5): 116-121. Mingen Xu*, Xiaohong Wang, Yongnian Yan, Rui Yao, Yakun Ge. A cell-assembly derived physiological 3D model of the metabolic syndrome, based on adipose-derived stromal cells and a gelatin/alginate/fibrinogen matrix. Biomaterials, 2010, 31 (14): 3868 - 3877. Rui Yao, Renji Zhang, Xiaohong Wang*. Design and Evaluation of a Cell Microencapsulating Device for Cell Assembly Technology. Journal of Bioactive and Compatible Polymers, 2009; 24: 48 - 62. Rui Yao, Renji Zhang, Yongnian Yan, Xiaohong Wang*. In vitro Angiogenesis of Three-dimensional Tissue Engineered Adipose Tissue. Journal of Bioactive and Compatible Polymers, 2009; 24: 5 - 24.