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个人简介

教育背景 1990-1995 北京大学化学系,学士 1995-2001 美国 The University of Iowa化学系,博士 1998-2001 美国 The University of Iowa计算机科学系,硕士 工作履历 2002-2005 美国 Ames Lab / Iowa State University化学系,博士后 2005-2016 湖南大学化学化工学院,教授,博士生导师 2016- 清华大学化学系,教授,博士生导师

研究领域

生命分析化学(研究方向:基于单分子单细胞分析的复杂活性体系研究)

近期论文

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Pan, Q.; Sun, D.; Xue, J.; Hao, J.; Zhao, H.; Lin, X.; Yu, L.;He, Y.*, Real-Time Study of Protein Phase Separation with Spatiotemporal Analysis of Single Nanoparticle Trajectories.ACS Nano,2021, 15 (1), 539-549. Feng, J.; Zhang, Z.; Wen, X.; Xue, J.;He, Y.*, Single Nanoparticle Tracking Reveals Efficient Long-Distance Undercurrent Transport in Upper Fluid of Bacterial Swarms.iScience,2019, 22: 123-132. Pan, Q.; Zhao, H.; Lin, X.;He, Y.*,Spatiotemporal Heterogeneity of Reactions in Solution Observed with High Speed Single Nanorod Rotational Sensing.Angewandte Chemie International Edition,2019, 58 (25), 8389-8393. Peng, Y.; Xiong, B.; Peng, L.; Li, H.; He, Y.*; Yeung, E. S.*, Recent Advances in Optical Imaging with Anisotropic Plasmonic Nanoparticles. Anal. Chem. 2015, 87 (1), 200-215. Xu, D.; He, Y.*; Yeung, E. S., Direct Observation of the Orientation Dynamics of Single Protein-Coated Nanoparticles at Liquid/Solid Interfaces. Angew. Chem. Int. Ed. 2014, 53 (27), 6951-6955. Xiong, B.; Zhou, R.; Hao, J.; Jia, Y.; He, Y.*; Yeung, E. S., Highly sensitive sulphide mapping in live cells by kinetic spectral analysis of single Au-Ag core-shell nanoparticles. Nat. Commun. 2013, 4:1708. Zhou, R.; Zhou, H.; Xiong, B.; He, Y.*; Yeung, E. S., Pericellular Matrix Enhances Retention and Cellular Uptake of Nanoparticles. J. Am. Chem. Soc. 2012, 134 (32), 13404-13409. Xiao, L.; Qiao, Y.; He, Y.*; Yeung, E. S., Imaging Translational and Rotational Diffusion of Single Anisotropic Nanoparticles with Planar Illumination Microscopy. J. Am. Chem. Soc. 2011, 133 (27), 10638-10645. Hao, J.; Xiong, B.; Cheng, X.; He, Y.*; Yeung, E. S., High-Throughput Sulfide Sensing with Colorimetric Analysis of Single Au–Ag Core–Shell Nanoparticles. Anal. Chem. 2014, 86 (10), 4663-4667. Xu, D.; He, Y.*; Yeung, E. S., Direct Imaging of Transmembrane Dynamics of Single Nanoparticles with Darkfield Microscopy: Improved Orientation Tracking at Cell Sidewall. Anal. Chem. 2014, 86 (7), 3397-3404. Cheng, X.; Dai, D.; Xu, D.; He, Y.*; Yeung, E. S., Subdiffraction-Limited Plasmonic Imaging with Anisotropic Metal Nanoparticles. Anal. Chem. 2014, 86 (5), 2303-2307. Xiao, L.; Wei, L.; Cheng, X.; He, Y.*; Yeung, E. S., Noise-Free Dual-Wavelength Difference Imaging of Plasmonic Resonant Nanoparticles in Living Cells. Anal. Chem. 2011, 83 (19), 7340-7347. Cheng, J.; Liu, Y.; Cheng, X.; He, Y.*; Yeung, E. S., Real Time Observation of Chemical Reactions of Individual Metal Nanoparticles with High-Throughput Single Molecule Spectral Microscopy. Anal. Chem. 2010, 82 (20), 8744-8749.

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