个人简介

1999 - 2004 PhD. Science, University of Liege, Belgium (Dr. M. Hoebeke and Dr. M.P. Fontaine-Aupart) 1993 - 1997 B.Sc. Science, University of Liege, Belgium (Honours Dr. J. Beckers) 1993 - 1997 B. Sc. Education, University of Liege, Belgium

研究领域

bio-physical

Our research is highly multidisciplinary from synthesis to cell culture, our aim is to use photochemistry to understand and control the production of reactive oxygen species in biological environment.

近期论文

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V.L. Trudeau, B. Heyne, J. Blais, F. Temussi, S. Atkinson, F. Pakdel, J. Popesku, V. Marlatt, J.C. Scaiano, L. Previtera, D. Lean, 2011, “Lumiestrone is photochemically derived from estrone and is being released to the environment without detection.”, Frontiers in Experimental Endocrinology, 2: 83. J.F. Araneda, W.E. Piers, B. Heyne, M. Parvez and R. McDonald, 2011, “High Stokes Shift Anilido-Pyridine Boron Difluoride Dyes.”, Angew. Chem., Int. Ed., 50 (51), 12214-12217. J.C. Netto-Ferreira, B. Heyne and J.C. Scaiano, 2011, “Photophysics and Photochemistry of Aflatoxins B1 and B2”, Photochemical and Photobiological Science, 10 (10), 1701 - 1708. A.Z. Valencia-Perez and B. Heyne, 2010, “Singlet oxygen induces fluorescent proteins dimerization.”, ChemBioChem, 11(17): 2384–2388. T. Bitew, C. Sveen, B. Heyne and V. Zaremberg, 2010, “Vitamin E prevents lipid raft modifications induced by an anti-cancer lysophospholipid and abolishes a Yap1 mediated stress response in yeast.”, J. Biol. Chem., 285: 25731-25742. V. Lau and B. Heyne, 2010, “Calix[4]arene sulfonate as a template for forming fluorescent thiazole orange H-aggregates”, Chemical Communications, 46, 3595-3597. J.J. Harrison, V. Tremaroli V., M.A. Stan, C.S. Chan, C. Vacchi-Suzzi, B.J. Heyne, M.R. Parsek, H. Ceri and R.J. Turner, 2009, “Chromosomal antioxidant genes have metal ion-specific roles as determinants of bacterial metal tolerance”, Environmental Microbiology, 11(10), 2491-509. V. Lau and B. Heyne, 2009, “Does the DNA binding mode of a molecule affect its ability to interact with singlet oxygen?”, Photochemistry and Photobiology, 85, 1110-1115. W. Liu, C. Deng, C.R. McLaughlin, P. Fagerholm, N.S. Lagali, B. Heyne, J.C. Scaiano, M.A. Watsky, Y. Kato, R. Munger, N. Shinozaki, F. Li, M. Griffith, 2009, “Collagen-phosphorylcholine interpenetrating network hydrogels as corneal substitutes”, Biomaterials, 30(8), 1551-1559. W. Liu, K. Merrett, M. Griffith, P. Fagerholm, S. Dravida, B. Heyne, J.C. Scaiano, M.A. Watsky, N. Shinozaki, N. Lagali, R. Munger, F. Li, 2008, “Recombinant human collagen for tissue engineered corneal substitutes.”, Biomaterials, 29(9), 1147-1158. Heyne B., Ahmed S., Scaiano J.C., 2008, “Mechanistic Studies of Fluorescent Sensors for the Detection of Reactive Oxygen Species.”, Organic Biomolecular Chemistry, 6: 354-358. Heyne B., Beddie C., Scaiano J.C., 2007, “Design of a new fluorescent probe for reactive oxygen species.”, Organic Biomolecular Chemistry, 5(9): 1454-1458. Heyne B., Tfibel F., Hoebeke M., Hans P., Maurel V., Fontaine-Aupart M.-P. *, 2006, “Photochemistry of 2,6-diisopropylphenol (propofol)”, Photochemical and Photobiological Sciences, 5(11): 1059-1067. Delanaye L., Bahri M.A., Tfibel F., Fonatine-Aupart M.-P., Mouithys-Mickalad A., Heyne B., Piette J., Hoebeke M., 2006, “Physical and chemical properties of pyropheophorbide-a methyl ester in ethanol, phosphate buffer and aqueous dispersion of small unilamellar dimyristoyl-L-alpha-phosphatidylcholine vesicles.”, Photochemical and Photobiological Sciences, 5(3): 317-325. Attention error, published as Heine B. Heyne B., Maurel V., Scaiano J.C., 2006, “Mechanism of action of sensors for reactive oxygen species based on fluorescein-phenol coupling: the case of 2-[6-(4'-hydroxy)phenoxy-3H-xanthen-3-on-9-yl]benzoic acid.”, Organic Biomolecular Chemistry, 4(5):802-807. Heyne B., Brault D., Fontaine-Aupart M.-P., Kohnen S., Tfibel F., Mouithys-Mickalad A., Deby-Dupont G., Hans P. and Hoebeke M., 2005, “Reactivity towards singlet oxygen of propofol inside liposomes and neuronal cells.”, Biochimica et Biophysica Acta, 1724, 100-107. Bahri M.A., Heyne B.J., Hans P., Seret A.E., Mouithys-Mickalad A.A. and Hoebeke M.D., 2005, “Quantification of lipid bilayer effective microviscosity and fluidity effect induced by propofol”, Biophysical Chemistry, 114, 53-61. Heyne B., Kohnen S., Brault D., Mouithys-Mickalad A., Tfibel F., Hans P., Fontaine-Aupart M.-P., Hoebeke M., 2003, “Investigation of the singlet oxygen reactivity towards Propofol”, Photochemical and Photobiological Sciences, 2, 939-945. A. Giuliani, I.C. Walker, J. Delwiche, S.V.Hoffmann, P. Limao-Vieira, N.J. Mason, B. Heyne, M. Hoebeke and M.-J. Hubin-Franskin, 2003, “The electronic states of 2-furanmethanol (furfuryl alcohol) studied by photon absorption and electron impact spectroscopies”, Journal of Chemical Physics, 119(14), 7282-7288.