个人简介
1989年毕业于华中科技大学物理系,1992年吉林大学理学硕士,1998年德国魏尔茨堡大学自然科学博士,同年到伊利诺伊大学芝加哥分校做博士后,2001年到物理所工作。2003年获国家“杰出青年”科学基金。IUPAP生物物理委员会委员(2015-2017;2018-2020), 中国晶体学会常务理事(2016-2019),中国生物物理学会常务理事(2018-2021)。现任中科院物理所研究员、学术委员会委员、SM4课题组组长
研究领域
单分子生物物理与技术 (分子马达、DNA修复、膜蛋白动力学、跨膜转运;单分子方法)
1)生物分子机器的运行原理
2)膜蛋白的跨膜与响应动力学
3)染色质的组装与调控
近期论文
查看导师新发文章
(温馨提示:请注意重名现象,建议点开原文通过作者单位确认)
Functions of FACT in Breaking the Nucleosome and Maintaining Its Integrity at the SingleNucleosome Level, Molecular Cell 71: 284–293, 2018
Helicase Stepping Investigated with One-Nucleotide Resolution Fluorescence Resonance Energy Transfer, Wenxia Lin, Jianbing Ma, Daguan Nong, Chunhua Xu, Bo Zhang, Jinghua Li, Qi Jia, Shuoxing Dou, Fangfu Ye, Xuguang Xi, Ying Lu, and Ming Li, Phys. Rev. Lett. 119, 138102 (2017)
FACT Remodels the Tetranucleosomal Unit of Chromatin Fibers for Gene Transcription. Wei Li, Ping Chen, Juan Yu, Liping Dong, Dan Liang, Jianxun Feng, Jie Yan, Peng-Ye Wang, Qing Li, Zhiguo Zhang, Ming Li and Guohong Li, Molecular Cell, 64: 120-133, 2016
Single molecule visualization of dynamic transitions of pore-forming peptides among multiple transmembrane positions. Ying Li, Zhenyu Qian, Li Ma, Shuxin Hu, Daguan Nong, Chunhua Xu, Fangfu Ye, Ying Lu, Guanghong Wei & Ming Li, Nature Communications, 7: 12906. 2016
Pif1 is a force-regulated helicase. Li,Jing-Hua; Lin,Wen-Xia; Zhang,Bo; Nong,Da-Guan; Xu,Chun-Hua; Ye,Fang-Fu; Xi,Xu Guang; Li,Ming; Lu,Ying; and Dou,Shuo-Xing, Nucleic Acids Research, 44: 4330-4339, 2016
Unwinding forward and sliding back: an intermittent unwinding mode of the BLM helicase. Shuang Wang, Wei Qin, Jing-Hua Li, Ying Lu, Ke-Yu Lu, Da-Guan Nong, Shuo-Xing Dou, Chun-Hua Xu, Xu-Guang Xi and Ming Li, Nucleic Acids Research, 43: 3736–3746, 2015
Direct Measurement of Sequential Folding Pathway and Energy Landscape of Human Telomeric G-quadruplex Structures. Li,Wei; Hou,Xi-Miao; Wang,Peng-Ye; Xi,Xu-Guang; and Li Ming, Journal of the American Chemical Society, 135: 6423−6426,2013
Impact of DNA Twist Accumulation on Progressive Helical Wrapping of Torsionally Constrained DNA. Li,Wei; Wang,Peng-Ye; Yan,Jie; Li,Ming, Physical Review Letters,109(21):218102,2012