Lu, Chung-Dar - Georgia State University

个人简介

Ph.D. Molecular Genetics & Biochemistry Georgia State University 1991 Molecular Genetics and Biochemistry Research Group Molecular Genetics and Microbiology

研究领域

The main research interests of the LU group are (i) the metabolic versatility and regulatory mechanisms in P. aeruginosa; and (ii) exploration of new molecular targets for antibacterial development. Currently we are working on three projects: 1. Functional Genomics of D-Amino Acid Metabolism in P. aeruginosa 2. Molecular Mechanisms of Resistance and Stress Response against Polyamine Toxicity in Bacteria 3. Modulation of Type III Secretion System (T3SS) in P. aeruginosa by Environmental Cues

近期论文

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Induction of the pho regulon and polyphosphate synthesis against spermine stress in Pseudomonas aeruginosa. Peng YC, Lu C, Li G, Eichenbaum Z, Lu CD. Mol Microbiol. 2017 Jun;104(6):1037-1051. doi: 10.1111/mmi.13678. Epub 2017 Apr 12. Molecular characterization of LhpR in control of hydroxyproline catabolism and transport in Pseudomonas aeruginosa PAO1. Li G, Lu CD. Microbiology. 2016 Jul;162(7):1232-42. doi: 10.1099/mic.0.000300. Epub 2016 May 4. Molecular characterization of lysR-lysXE, gcdR-gcdHG and amaR-amaAB operons for lysine export and catabolism: a comprehensive lysine catabolic network in Pseudomonas aeruginosa PAO1. Madhuri Indurthi S, Chou HT, Lu CD. Microbiology. 2016 May;162(5):876-88. doi: 10.1099/mic.0.000277. Epub 2016 Mar 11. The Cryptic dsdA Gene Encodes a Functional D-Serine Dehydratase in Pseudomonas aeruginosa PAO1. Li G, Lu CD. Curr Microbiol. 2016 Jun;72(6):788-94. doi: 10.1007/s00284-016-1021-0. Epub 2016 Mar 8. Feedback control of prion formation and propagation by the ribosome-associated chaperone complex. Kiktev DA, Melomed MM, Lu CD, Newnam GP, Chernoff YO. Mol Microbiol. 2015 May;96(3):621-32. doi: 10.1111/mmi.12960. Epub 2015 Mar 11. A novel Pseudomonas aeruginosa strain with an oprD mutation in relation to a nosocomial respiratory infection outbreak in an intensive care unit. Yan Y, Yao X, Li H, Zhou Z, Huang W, Stratton CW, Lu CD, Tang YW. J Clin Microbiol. 2014 Dec;52(12):4388-90. doi: 10.1128/JCM.02782-14. Epub 2014 Oct 8. Functional characterization of the dguRABC locus for D-Glu and d-Gln utilization in Pseudomonas aeruginosa PAO1. He W, Li G, Yang CK, Lu CD. Microbiology. 2014 Oct;160(Pt 10):2331-40. doi: 10.1099/mic.0.081141-0. Epub 2014 Jul 31. Characterization of Staphylococcus aureus responses to spermine stress. Yao X, Lu CD. Curr Microbiol. 2014 Sep;69(3):394-403. doi: 10.1007/s00284-014-0603-y. Epub 2014 May 11.