Kaur, Parjit - Georgia State University

个人简介

Ph.D. Microbiology Panjab University 1986 Molecular Genetics and Biochemistry Molecular Genetics of Membrane Transport

研究领域

The focus of research in this laboratory is on understanding function of membrane transport proteins. Transport of nutrients into or toxic substances out of the cell is integral to life, and is carried out by dedicated proteins located in the cell membrane. Most transport processes require input of energy – either in the form of ATP or membrane potential. When ATP is the source of energy, transport also requires the function of a dedicated ATPase. Four major classes of transport ATPases are known: F, A, P, and ABC. The molecular mechanisms of transport ATPases are poorly understood. It is not known how the energy is transduced to carry out transport, or what determines the polarity of transport. An intriguing question also concerns the substrate specificty of the transport proteins.

近期论文

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Using Atomic Force Microscopy to Characterize the Conformational Properties of Proteins and Protein-DNA Complexes That Carry Out DNA Repair. LeBlanc S, Wilkins H, Li Z, Kaur P, Wang H, Erie DA. Methods Enzymol. 2017;592:187-212. doi: 10.1016/bs.mie.2017.04.004. Epub 2017 Jun 16. Design of anti-thyroid drugs: Binding studies and structure determination of the complex of lactoperoxidase with 2-mercaptoimidazole at 2.30 Å resolution. Sirohi HV, Singh PK, Iqbal N, Sharma P, Singh AK, Kaur P, Sharma S, Singh TP. Proteins. 2017 Jun 27. doi: 10.1002/prot.25342. [Epub ahead of print] CpG and methylation-dependent DNA binding and dynamics of the methylcytosine binding domain 2 protein at the single-molecule level. Pan H, Bilinovich SM, Kaur P, Riehn R, Wang H, Williams DC Jr. Nucleic Acids Res. 2017 Jun 20. doi: 10.1093/nar/gkx548. [Epub ahead of print] Morphometric and scanning electron microscopy based identification of Ancylostoma caninum parasites in dog. Uppal HS, Bal MS, Singla LD, Kaur P, Sandhu BS. J Parasit Dis. 2017 Jun;41(2):517-522. doi: 10.1007/s12639-016-0841-y. Epub 2016 Oct 7. Detection of anthelmintic resistance in sheep and goat against fenbendazole by faecal egg count reduction test. Singh R, Bal MS, Singla LD, Kaur P. J Parasit Dis. 2017 Jun;41(2):463-466. doi: 10.1007/s12639-016-0828-8. Epub 2016 Aug 23. Effect of rhizobacteria on arsenic uptake by macrophyte Eichhornia crassipes (Mart.) Solms. Kaur P, Singh S, Kumar V, Singh N, Singh J. Int J Phytoremediation. 2017 Jun 14:0. doi: 10.1080/15226514.2017.1337071. [Epub ahead of print] Body dysmorphic disorder: Diagnosis, clinical aspects and treatment strategies. Ahluwalia R, Bhatia NK, Kumar PS, Kaur P. Indian J Dent Res. 2017 Mar-Apr;28(2):193-197. doi: 10.4103/ijdr.IJDR_669_15. Review. Recent Advances In Pathophysiology Of Traumatic Brain Injury. Kaur P, Sharma S. Curr Neuropharmacol. 2017 Jun 12. doi: 10.2174/1570159X15666170613083606. [Epub ahead of print]