梁璐 - 广州医科大学

个人简介

广州医科大学药学院讲师,2017年于香港科技大学博士毕业,2013年于东北林业大学获取医学硕士，2006、2007分别于东北林业大学和哈尔滨师范大学获取理学学士和实用日本语文学学士。曾从事肺癌转移的基础生物学研究，抗肿瘤药物、抗雌激素药物、抗氧化药物的筛选

研究领域

1、从事肺癌转移的基础生物学研究，研究初级纤毛在肺癌转移中扮演的角色，进一步揭示肺癌转移与纤毛形成有关靶基因的关系。 2、在细胞水平上建立一个国内先进的生物活性筛选、分析和评价体系。筛选和分析多种天然产物中有效活性物质；开发具有独特生物活性安全有效的纯天然抗肿瘤、抗病毒、抗氧化、抗感染的产品；研究和开发新型高效低毒药物。 3、从事肿瘤心脏病学的研究，降低常见抗肿瘤药物对心脏功能的毒副作用。减轻化疗对肿瘤患者生活方式的改变及带来的间接损伤

近期论文

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(1) Lu Liang#, Meng Luo#, Yujie Fu*, Yuangang Zu, Wei Wang, Chengbo Gu, Chunjian Zhao, Chunying Li and Thomas Efferth, Cajaninstilbene acid (CSA) exerts cytoprotective effects against oxidative stress through the Nrf2-dependent antioxidant pathway, Toxicology Letters, 2013, 219(3): 254-261. (2) Lu Liang#, Chang Gao#, Meng Luo, Wei Wang, Chunjian Zhao, Chunying Li, Yuangang Zu, Thomas Efferth and Yujie Fu*. Dihydroquercetin (DHQ) induce HO-1 and NQO1 expression against oxidative stress through the Nrf2-dependent antioxidant pathway, Journal of Agricultural and Food Chemistry, 2013, 61(11): 2755-2761. (3) Lu Liang, Chang Gao, Meng Luo, Chunjian Zhao, Wei Wang, Chengbo Gu, Jinghua Yu, and Yujie Fu*. The Phytoestrogenic Compound Cajanol from Pigeonpea Roots is Associated with the Activation of Estrogen Receptor α-dependent Signaling Pathway in Human Prostate Cancer Cells, Phytotherapy Research, 2013, 27(12): 1834-1841. (1) Yechang Shao, Lu Liang, Linjing Shi, Chengsong Wan*, Shouyi Yu, The Effect of Social Support on Glycemic Control in Patients with Type 2 Diabetes Mellitus: The Mediating Roles of Self-Efficacy and Adherence, J Diabetes Res, 2017, 2017: 2804178. (2) Ru-Jian Yu#, Hai-Bin Liu#, Yang Yua, Lu Liang, Rui Xu, Chun Liang*, Jin-Shan Tang*, Xin-Sheng Yao*, Anticancer activities of proanthocyanidins from the plant Urceola huaitingii and their synergistic effects in combination with chemotherapeutics, Fitoterapia, 2016, 112: 175-182. (3) Yining Huang, Aftab Amin, Yan Qin, Ziyi Wang, Huadong Jiang, Lu Liang, Linjing Shi, Chun Liang*, A Role of hIPI3 in DNA Replication Licensing in Human Cells, Plos One, 2016, 11(4): e0151803. (4) Yuan Gao, Jintong Zhao, Yuangang Zu, Yujie Fu*, Lu Liang, Meng Luo, Wei Wang, Thomas Efferth, Antioxidant properties, effects on Superoxide Dismutase and Glutathione Reductase activities in HepG2 cells with a fungal endophyte producing Apigenin from Pigeon Pea [Cajanus cajan (L.) Millsp.], Food Research International, 2012, 49(1): 147-152. (5) Yuangang Zu#, Huimin Yu#, Lu Liang, Yujie Fu*, Thomas Efferth, Xia Liu and Nan Wu, Activities of Ten Essential Oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 Cancer Cells, Molecules, 2010, 15(5): 3200-3210. (6) Yu Kong#, Wei Ma#, Xia Liu, Yuangang Zu, Yujie Fu* Nan Wu, Lu Liang, Liping Yao, Thomas Efferth. Cytotoxic Activity of Curcumin towards CCRF-CEM Leukemia Cells and Its Effect on DNA Damage, Molecules, 2009, 14(12): 5328-5338.