赵昕 - 广州医科大学

个人简介

2012年于中国科学院广州生物医药与健康研究院取得药物化学专业博士学位。2012年-2016年于中国科学院广州生物医药与健康研究院历任助理研究员、副研究员。2016年国家公派赴美国亚利桑那大学进行访问研究。2017年任广州医科大学药学院副教授。

研究领域

目前研究集中于药物化学生物学领域开展具有生物活性小分子的设计、合成及作用机制研究。

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Xie, H.; Zeng, S.; He, Y.; Zhang, G.; Yu, P.; Zhong, G.; Xu, H.; Yang, L.; Wang, S.; Zhao, X*, Hu, W*. Rapid generation of a novel DPP-4 inhibitor with long-acting properties: SAR study and PK/PD evaluation. Eur. J. Med. Chem., 2017, 141, 519-529. 2. Li, R.; Yang, C.; Du, Q.; Zhao, X; Jiang, H.; Hu, W*; Yang, Z *. Pinanamine Is a Promising Lead Compound against Influenza A Virus: Evidence from in Vitro and in Vivo Efficacy Compared to Amantadine. Biol. Pharm. Bull. 2017, 40, 954–959 3. Zhao, X*; Zhang, Z. W.‡; Cui, W.; Chen, S, Zhou, Y.; Dong, J.; Jie, Y.; Wan, J.; Xu, Y.*; Hu, W.* Identification of camphor derivatives as novel M2 ion channel inhibitors of influenza A virus. Med. Chem. Comm. 2015, 6,727-731 4. Cui, W.; Chen, S.; Wu, J. Q.; Zhao, X*; Hu, W.*; Wang, H.* Palladium-Catalyzed Remote C(sp3)−H Arylation of 3‑Pinanamine. Org. Lett., 2014, 16, 4288−4291. 5. Zhao, X; Jie, Y.; Rosenberg, M. R.; Wan, J.; Zeng, S.; Cui, W.; Xiao, Y.; Li, Z.; Tu, Z.; Casarotto, M. G.; Hu, W.* Design and synthesis of pinanamine derivatives as anti-influenza A M2 ion channel inhibitors. Antiviral Res, 2012, 96, 91–99. 6. Zhao, X.; Li, C.; Zeng, S, Hu, W* Discovery of highly potent agents against influenza A virus. Eur. J. Med. Chem. 2011, 46, 52–57. 7. Xie, H.; Zeng, L; Zeng, S.; Lu, X.; Zhao, X..; Zhang, G.; Tu, Z.; Xu, H.; Yang, L.; Zhang, X.; Wang, S.; Hu W*. Highly potent dipeptidyl peptidase IV inhibitors derived from Alogliptin through pharmacophore hybridization and lead optimization. Eur. J. Med. Chem. 2013, 68, 312–320. 8. Zeng, S.; Xie, H.; Zeng, L; Lu, X.; Zhao, X.; Zhang, G.; Tu, Z.; Xu, H.; Yang, L.; Zhang, X.; Hu W*. Discovery of potent dipeptidyl peptidase IV inhibitors through pharmacophore hybridization and hit-to-lead optimization. Bioorg. Med. Chem., 2013, 21, 1749-1755. 9. Xie, H.; Zeng, L.; Zeng, S.; Lu, Xin.; Zhang, G.; Zhao, X.; Cheng, N.; Tu, Z.; Li, Z.; Xu, H.; Yang, L.; Zhang, X.; Huang, M.; Zhao, J.; Hu, W*. Novel pyrrolopyrimidine analogues as potent dipeptidyl peptidase IV inhibitors based on pharmacokinetic property-driven optimization. Eur. J. Med. Chem. 2012, 52, 205–212.