张曼 - 广州医科大学

个人简介

香港浸会大学中医药学院访问学者并获得博士学位。近年来主要从事药理毒理学及中药学方面的研究，

研究领域

近年来主要从事药理毒理学及中药学方面的研究，主要包括：蛇毒、蝎毒等生物毒素抗炎组分的分离、抗炎机制、毒理机制、内脏痛与胃肠运动功能紊乱、溃疡性结肠炎病理生理机制及治疗的研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. 赵莉，覃媛，蔡轶，顾少菊，卞兆祥，张曼(通讯作者）. 新生期母子分离对大鼠2型糖尿病进程的影响. 暨南大学学报( 自然科学与医学版).2017;38(1):69-74 2. Li YH, Zhang M（共同一作）, Xiao HT, Fu HB, Ho A, Lin CY, Huang Y, Lin G, Bian ZX. Addition of Berberine to 5-Aminosalicylic Acid for Treatment of Dextran Sulfate Sodium-Induced Chronic Colitis in C57BL/6 Mice. PLoS One. 2015 Dec 7;10(12):e0144101. 3. Hu DD, Han QB, Zhong LL, Li YH, Lin CY, Ho HM, Zhang M, Lin SH, Zhao L, Huang T, Mi H, Tan HS, Xu HX, Bian ZX. Simultaneous determination of ten compounds in rat plasma by UPLC-MS/MS: Application in the pharmacokinetic study of Ma-Zi-Ren-Wan. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Sep 1;1000:136-46. 4. Lin CY, Zhang M（共同一作）, Huang T, Yang LL, Fu HB, Zhao L, Zhong LL, Mu HX, Shi XK, Leung CF, Fan BM, Jiang M, Lu AP, Zhu LX, Bian ZX. Spexin Enhances Bowel Movement through Activating L-type Voltage-dependent Calcium Channel via Galanin Receptor 2 in Mice. Sci Rep. 2015 Jul 10;5:12095. 5. Cai Y, Zhao L, Qin Y, Zhang M, He Y. Resveratrol inhibits proliferation and induces apoptosis of nasopharyngeal carcinoma cell line C666-1 through AMPK activation. Pharmazie 70: 399-403, 2015. 6. 覃媛，张曼，黄劭，顾少菊. 东亚钳蝎钙通道样毒素的重组表达及活性研究.实用医学杂志. 2015；31(16):2611-2614 7. 顾少菊，覃媛，黄劭，张曼(通讯作者). 眼镜蛇毒C组份对白血病细胞中的MMP-2和MMP-9的表达影响. 广东医学，2014，35（5）：645-647 8. Xiao HT, Lin CY, Ho DH, Peng J, Chen Y, Tsang SW, Wong M, Zhang XJ, Zhang M, Bian ZX (Corresponding author). Inhibitory effect of the gallotannin corilagin on dextran sulfate sodium-induced murine ulcerative colitis. J Nat Prod. 2013 Nov 22;76(11):2120-5. 9. Zhang M, Zang KH, Luo JL, Leung FP, Huang Y, Lin CY, Yang ZJ, Lu AP, Tang XD, Xu HX, Sung JJ, Bian ZX (Corresponding author). Magnolol inhibits colonic motility through down-regulation of voltage-sensitive L-type Ca2+ channels of colonic smooth muscle cells in rats. Phytomedicine. 2013; 20(14):1272-9. 10. 郭绮祺，刘静雯，王方宇，张曼(通讯作者). 罗红霉素和四磨汤联合用药对小鼠胃肠运动与胃动素的影响. 新中医.2013,45(8):195-197 11. 张曼, 顾少菊, 孔天翰, 黄劭, 覃媛. 蝎毒多肽促进创伤皮肤溃疡愈合的实验研究.中国医药导报.2012;9(10):22-23 12. Zhang M, Leung FP, Huang Y, Bian ZX (Corresponding author). Increased colonic motility in a rat model of irritable bowel syndrome is associated with up-regulation of L-type calcium channels in colonic smooth muscle cells. Neurogastroenterol Motil. 2010 22(5): e162-70. 13. Bian ZX (Corresponding author), Zhang M, Han QB, Xu HX, Sung JJ. Analgesic effects of JCM-16021 on neonatal maternal separation-induced visceral pain in rats. World J Gastroenterol. 2010, 21;16 (7):837-45. 14. Bian ZX (Corresponding author), Li Z, Huang ZX, Zhang M, Chen HL, Xu HX, Sung JJ.J Unbalanced expression of protease-activated receptors-1 and -2 in the colon of diarrhea-predominant irritable bowel syndrome patients. J Gastroenterol. 2009; 44(7):666-74.