个人简介
2012年毕业于中山大学药学院获理学博士学位。2012年进入广州医科大学药学院从事教学和科研工作,2017年入选广州医科大学“南山学者”人才计划,主要研究方向为心血管药理学和中药药理学。目前,作为项目负责人主持国家自然科学基金1项,广东省自然科学基金2项,广州市科技计划-科学研究专项1项,广州市教育局市属高校科研项目1项。指导本科生获得国家级大学生创新创业训练计划立项项目、广东大学生科技创新培育专项、广州医科大学课外科研重点项目等多项科研立项。近年来,在Toxicol Appl Pharmacol、Arch Biochem Biophys、 Br J Pharmacol、FEBS Lett等杂志上发表SCI论文10余篇。
近期论文
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(1) Xiao, Y., Ye, J., Zhou, Y., Huang, J., Liu, X., Huang, B., Zhu, L., Wu, B., Zhang, G. & Cai, Y *. (2018) Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-beta/Smads signaling pathway, Arch Biochem Biophys. 640, 37-46. (corresponding author) (2) Cai Y *, W. Ma, Y. Xiao, B. Wu, X. Li, F. Liu, J. Qiu, G. Zhang*, High doses of baicalin induces kidney injury and fibrosis through regulating TGF-beta/Smad signaling pathway, Toxicol Appl Pharmacol. 333 (2017) 1-9. (corresponding author) (3) Cai Y*, He SQ, Hong HQ, Cai YP, Zhao L, Zhang M. High doses of (-)-epigallocatechin-3-gallate from green tea induces cardiac fibrosis in mice. Biotechnol Lett. 2015, 37(12): 2371-2377. (corresponding author) (4) Cai Y*, Hong HQ, Zhao L, Cai YP, Qin Y. (-)-Epicatechin-3-gallate (a polyphenol from green tea) potentiates doxorubicin-induced apoptosis in H9C2 cardiomyocytes. Biotechnol Lett. 2015, 37(10): 1937-1943. (corresponding author) (4) Cai Y*, Zhao L, Qin Y, He Y. High dose of epigallocatechin-3-gallate inhibits proliferation and induces apoptosis of H9C2 cardiomyocytes through down-regulation of SIRT1. Pharmazie. 2015, 70(1): 12-16. (corresponding author) (6) Cai Y*, Zhao L, Qin Y, Wu XQ*. EGCG Blocked Phenylephrin-Induced Hypertrophy in H9C2 Cardiomyocytes, by Activating AMPK-Dependent Pathway. Korean J Physiol Pharmacol. 2015, 19(3): 203-210. (corresponding author) (7) Cai Y*, Zhao L, Qin Y, Zhang M, He Y. Resveratrol inhibits proliferation and induces apoptosis of nasopharyngeal carcinoma cell line C666-1 through AMPK activation. Pharmazie. 2015, 70(6): 399-403. (corresponding author) (8) Cai Y#, Yu SS, Chen TT, Gao S, Geng B, Yu Y, Ye JT*, Liu PQ*. EGCG inhibits CTGF expression via blocking NF-kappaB activation in cardiac fibroblast. 2013, Phytomedicine 20(2): 106-113. (9) Cai Y#, Yu SS, Chen SR, Pi RB, Gao S, Li H, Ye JT*, Liu PQ*. Nmnat2 protects cardiomyocytes from hypertrophy via activation of SIRT6. 2012, FEBS Lett 586(6): 866-874. (10)Yu SS#, Cai Y#, Ye JT, Pi RB, Chen SR, Liu PQ*, Shen XY*, Ji Y*. Sirtuin 6 protects cardiomyocytes from hypertrophy in vitro via inhibition of NF-kappaB-dependent transcriptional activity. 2013, Br J Pharmacol 168(1): 117-128. (co-first author) (11) Geng B#, Cai Y#, Gao S, Lu J, Zhang L, Zou J, Liu M, Yu S, Ye J*, Liu P*. PARP-2 knockdown protects cardiomyocytes from hypertrophy via activation of SIRT1. 2013, Biochem Biophys Res Commun 430(3): 944-950. (co-first author)