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个人简介

研究员,硕导、博导。主要从事生物材料、纳米医学、分子药剂学等相关研究。分别于2012年、2017年在武汉大学化学与分子科学学院获理学学士、理学博士学位,2017年加入广州医科大学药学院任特聘教授。主持中国科协“青年人才托举工程”项目,广东省自然科学基金-杰出青年科学基金项目,国家重点研发计划项目(子课题负责人),国家自然科学基金-青年科学基金项目,广州市科技计划项目等课题,参与国家自然科学基金-重点项目、面上项目、青年科学基金项目等课题。以第一/通讯作者在ACS Nano,Nano Lett.,Adv. Funct. Mater.,Biomaterials,Adv. Sci.,Small,J. Control. Release等杂志发表SCI研究论文40余篇,获授权国家发明专利8项。现任《Acta Pharm. Sin. B》、《Chinese Chemical Letters》、《药学学报》青年编委,国家自然科学基金评审,中国博士后科学基金评审,广东省、北京市、河南省自然科学基金评审,广东省科技厅、教育局项目评审,担任Adv. Mater.,Nano Today,ACS Nano,Adv. Sci.,Adv. Funct. Mater.,Biomaterials,Signal Transduct. Tar.、Acta Pharm. Sin. B,Bioact. Mater.,ACS Appl. Mater. Interfaces,Theranostics等40余个国际学术期刊评审。荣获广东省科技进步奖一等奖,广东省药理学会科技成果奖一等奖,广州医科大学黄大年式教师团队等奖励和荣誉。 2017.7-至今 广州医科大学药学院 教授 2014.9-2017.6 武汉大学化学与分子科学学院 博士 2012.9-2014.6 武汉大学化学与分子科学学院 硕士 2008.9-2012.6 武汉大学化学与分子科学学院 学士

研究领域

生物医用材料 药物控释载体 分子荧光探针 精准诊疗系统

近期论文

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Zhang W L, Chen H Q, Ding L Y, Gong J W, Zhang M R, Guo W Y, Xu P Y*, Li S Y*, Zhang Y L*. Trojan horse delivery of 4,4`-dimethoxychalcone for parkinsonian neuroprotection. Adv. Sci. 2021, 2004555. Fan G L, Deng F A, Zhou X, Liu L S, Huang J Q, Zhang D W, Sun Y X, Chen A L*, Cheng H*, Li S Y*. Plasma membrane targeted photodynamic O2 economizer for hypoxic tumor therapy. Biomaterials 2021, 273, 120854. Li X Y, Deng F A, Zheng R R, Liu L S, Liu Y B, Kong R J, Chen A L, Yu X Y, Li S Y*, Cheng H*. Carrier free photodynamic synergists for oxidative damage amplified tumor therapy. Small 2021, 2102470. Zhao L P, Zheng R R, Liu L S, Chen X Y, Guan R T, Yang N, Chen A L, Yu X Y*, Cheng H*, Li S Y*. Self-delivery oxidative stress amplifier for chemotherapy sensitized immunotherapy. Biomaterials 2021, 275, 120970. Zheng R R, Zhao L P, Chen X Y, Liu L S, Liu Y B, Chen X T, Wang C, Yu X Y, Cheng H*, Li S Y*. Metal-coordinated nanomedicine for combined tumor therapy by inducing paraptosis and apoptosis. J. Control. Release 2021, 336, 159-168. Yuan P, Deng F A, Liu Y B, Zheng R R, Rao X N, Qiu X Z, Zhang D W, Yu X Y, Cheng H*, Li S Y*. Mitochondria targeted O2 economizer to alleviate tumor hypoxia for enhanced photodynamic therapy. Adv. Health. Mater. 2021, 202100198. Zhao L P, Chen S Y, Zheng R R, Kong R J, Rao X N, Chen A L, Cheng H*, Zhang D W*, Li S Y*, Yu X Y*. Self-delivery nanomedicine for glutamine-starvation enhanced photodynamic tumor therapy. Adv. Health. Mater. 2021, 202102038. Zhao L P, Zheng R R, Huang J Q, Chen X Y, Deng F A, Liu Y B, Huang C Y, Yu X Y*, Cheng H*, Li S Y*. Self-delivery photo-immune stimulators for photodynamic sensitized tumor immunotherapy. ACS Nano 2020, 14, 17100-17113. Zhao L P, Zheng R R, Fan G L, Fan J H, Yuan P, Liu L S, Qiu X Z, Yu X Y*, Cheng H*, Li S Y*. Self-delivery nanomedicine for O2-economized photodynamic tumor therapy. Nano Lett. 2020, 20, 2062-2071. Cheng H, Fan G L, Fan J H, Yuan P, Deng F A, Qiu X Z, Yu X Y, Li S Y*, Epigenetics-inspired photosensitizer modification for plasma membrane-targeted photodynamic tumor therapy. Biomaterials 2019, 224, 119497. Cheng H, Fan J H, Zhao L P, Fan G L, Zheng R R, Qiu X Z, Yu X Y*, Li S Y*, Zhang X Z. Chimeric peptide engineered exosomes for dual-stage light guided plasma membrane and nucleus targeted photodynamic therapy. Biomaterials 2019, 211, 14-24. Cheng H, Zheng R R, Fan G L, Fan J H, Zhao L P, Jiang X Y, Yang B, Yu X Y*, Li S Y*, Zhang X Z. Mitochondria and plasma membrane dual-targeted chimeric peptide for single-agent synergistic photodynamic therapy. Biomaterials 2019, 188, 1-11. Cheng H*, X Y Jiang, Zheng R R, Zuo S J, Zhao L P, Fan G L, Xie B R, Yu X Y, Li S Y*,Zhang X Z. A biomimetic cascade nanoreactor for tumor targeted starvation therapy amplified chemotherapy. Biomaterials 2019, 195, 75-85. Cheng H, Yuan P, Fan G L, Zhao L P, Zheng R R, Yang B, Qiu X Z, Yu X Y, Li S Y*, Zhang X Z. Chimeric peptide nanorods for plasma membrane and nuclear targeted photosensitizer delivery and enhanced photodynamic therapy. Appl. Mater. Today. 2019, 16, 120-131.

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