Yigit, Mehmet V. - University at Albany-SUNY

个人简介

Postdoc. Harvard Medical School/Massachusetts General Hospital, 2008-2012 Ph.D. University of Illinois at Urbana-Champaign, 2008 M.S. Worcester Polytechnic Institute, 2003

研究领域

As a research group, we are working at the interface of Chemistry, Nanotechnology, Materials Science, Biology and Medicine. Students in our lab experience various techniques from multiple disciplines. Our team is highly motivated in engineering nanomaterials and their application in biomedical research.

近期论文

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Neil M. Robertson, Mustafa Salih Hizir, Mustafa Balcioglu, Muhit Rana, Hasan Yumak, Ozgur Ecevit and Mehmet V. Yigit*. “Monitoring the multitask mechanism of DNase I activity using graphene nano assemblies”, Bioconjugate Chemistry, 2015, 26 (4), pp 735–745. Zdravka Medarova, Mustafa Balcioglu and Mehmet V. Yigit*. “Controlling RNA expression in cancer using iron oxide nanoparticles detectable by MRI and in vivo optical imaging”, Methods Mol. Biol.,in press . Mustafa Balcioglu, Burak Buyukbekar, Mustafa S. Yavuz and Mehmet V. Yigit*. “Smart polymer functionalized graphene nano-devices for thermo-switch controlled biodetection”, ACS Biomaterials Science & Engineering, 2015, 1 (1), pp 27–36. Mustafa Salih Hizir, Mustafa Balcioglu, Muhit Rana, Neil Robertson and Mehmet V. Yigit*. “Simultaneous detection of circulating oncomiRs from body fluids for prostate cancer staging using nano-graphene oxide”, ACS Applied Materials & Interfaces, 2014, 6 (17), pp 14772–14778. Mustafa Balcioglu, Muhit Rana, Neil Robertson and Mehmet V. Yigit*. “DNA-Length-Dependent Quenching of Fluorescently Labeled Iron Oxide Nanoparticles with Gold, Graphene Oxide and MoS2 Nanostructures”, ACS Applied Materials & Interfaces, 6 (15), 2014, 12100–12110. Neil Robertson and Mehmet V. Yigit*. “The Role of miRNAs in Resistance to Breast Cancer Therapy”, Wiley Interdisciplinary Reviews RNA, 5(6), 2014. Muhit Rana, Mustafa Balcioglu, and Mehmet V. Yigit*. “Locked nucleic acid-modified antisense miR-10b oligonucleotides form stable duplexes on gold nanoparticles", BioNanoScience, 4(2), 2014, 195-200. Muhit Rana, Mustafa Balcioglu, Neil Robertson and Mehmet V. Yigit*. “Nano-graphene oxide as a novel platform for monitoring the effect of LNA modification in nucleic acid interactions”, Analyst, 2014, 139 (4), 714 - 720. Mustafa Balcioglu, Muhit Rana and Mehmet V. Yigit*. “Doxorubicin loading on graphene oxide, iron oxide and gold nanoparticle hybrid”, Journal of Materials Chemistry B, 2013, 1 (45), 6187 - 6193. Byunghee Yoo, Subrata K. Ghosh, Mohanraja Kumar, Anna Moore, Mehmet V. Yigit* and Zdravka Medarova*. “Design of Nanodrugs for miRNA Targeting in Tumor Cells", Journal of Biomedical Nanotechnology 10(6), 2014, 1114-1122. Byunghee Yoo, Amol Kavishwar, Subrata K. Ghosh, Mehmet V. Yigit, Anna Moore, and Zdravka Medarova. “Detection of miRNA Expression in Intact Cells Using Activatable Sensor Oligonucleotides”, Chemistry & Biology, 21(2), 2014, 199-204. Subrata K. Ghosh, Mehmet V. Yigit, Masashi Uchida, Alana W. Ross, Natalie Barteneva, Anna Moore and Zdravka Medarova. “Sequence-dependent combination therapy with doxorubicin and a survivin-specific small interfering RNA nanodrug demonstrates efficacy in models of adenocarcinoma”, International Journal of Cancer, 2014, 134 (7), 1758–1766. Mehmet V. Yigit, Subrata K. Ghosh, Mohanraja Kumar, Victoria Petkova, Anna Moore and Zdravka Medarova. “Context-dependent differences in miR-10b breast oncogenesis can be targeted for the prevention and arrest of lymph node metastasis” Oncogene, 2013, 32(12), 1530-1538. Ping Wang, Mehmet V. Yigit, Chongzhao Ran, Alana Ross, Lingling Wei, Guangping Dai, Zdravka Medarova and Anna Moore. “A Theranostic Small Interfering RNA Nanoprobe Protects Pancreatic Islet Grafts From Adoptively Transferred Immune Rejection” Diabetes, 2012, 61(12), 3247-3254. Mehmet V. Yigit, and Zdravka Medarova. "Iron Oxide Nanoparticles and Derivatives for Biomedical Imaging and Application in Cancer Diagnosis and siRNA Therapy” Nano and Micro Flow Systems for Bioanalysis, Editors: M.W.Collins & C.S.König, Chapter 1, Springer, 2013. Mehmet V. Yigit, Anna Moore and Zdravka Medarova. “Magnetic nanoparticles for cancer diagnosis and therapy” Pharmaceutical Research, 2012, 29(5), 1180-1188. Mehmet V. Yigit*, Anna Moore and Zdravka Medarova*. “In vivo application of gold nanoparticles for biomedical SERS imaging”, Am. J. Nucl. Med. Mol. Imaging, 2012, 2(2), 232-241. Mehmet V. Yigit, Leyun Zhu, Marytheresa A. Ifediba, Yong Zhang, Kevin Carr, Anna Moore, and Zdravka Medarova. “Noninvasive MRI-SERS imaging in living mice using an innately bimodal nanomaterial” ACS Nano, 2011, 5(2), 1056–1066. Ping Wang, Mehmet V. Yigit, Liangli Wei, Guangping Dai, Zdravka Medarova, and Anna Moore. “Combined small interfering RNA therapy and in vivo magnetic resonance imaging in islet transplantation” Diabetes, 2011, 60(2), 565-571. Mohanraja Kumar, Mehmet V. Yigit, Guangping Dai, Anna Moore and Zdravka Medarova. “Image-guided breast tumor therapy using a siRNA nano drug” Cancer Research, 2010, 70(19),7553-7561.