个人简介
广州医科大学药学院副院长。广东省药学会理事，广东省药理学会常务理事、肿瘤药理专业委员会副主任委员，广东省高校教学管理学会常务理事、药学教育专业委员会副主任委员，广东省抗癌药物专业委员会委员。主要从事新型抗AD、抗肿瘤药物的合成及药理活性研究。近年来主持或参与国家自然科学基金、省重大科技专项等各级科研项目15项，各类基金、项目经费总额590多万元，以第一作者、通讯作者等发表包括SCI论文等科研教学论文45篇，申报专利3项，获市级科技进步二等奖一项。
近期论文
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1. Wen-Hao Wu, Xin-Tong Liang, Guo-Quan Xie, Lang-Di Chen, Wei-Xiong Liu, Guo-Lin Luo, Pei-Quan Zhang, Li-Hong Yu, Xue-Hua Zheng, Hong Ji, Chao Zhang*.Synthesis and evaluation of novel ligustrazine derivatives as multi-targeted inhibitors for the treatment of Alzheimer's disease[J]. E J Med Chem , (accepted.) 2．Chao Zhang*, Lang-di Chen, Xin-tong Liang, Wei-xiong Liu, and Wen-hao Wu. Synthesis and biological evaluation of ligustrazine derivatives[J].Chem Nat Compd. 2017,53(1):114-117. 3. Min-Ting Lin, Si-Li Tang, Chao Zhang, Hu-Biao Chen, Wen-Jing Huang, Yun Liu, Jian-Ye Zhang.Euphorbia factor L2 induces apoptosis in A549 cells through the mitochondrial pathway[J]. Acta Pharmaceutica Sinica B,2017.1,7(1):59-64. 4．Chao Zhang*, Qiao-Yi Du, et al. Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as multi-targeted compounds against Alzheimer's disease[J].E J Med Chem, 2016.4,116:200-209 5．Xuehua Zheng,Yinuo Wu, Deyan Wu, Xinhua Wang, Chao Zhang, Xiaolei Guo, Hai-Bin Luo. 3D-QSAR studies of 3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl) benzoic acids as AKR1C3 inhibitors: Highlight the importance of molecular docking in conformation generation. Bioorg Med Chem Lett,2016,26(23): 5631- 5638 6. Siyan Liao, Jincan Chen, Guangquan Mo, Chao Zhang ,et al. A Computational Study of Binding between 3-(4-fluorophenyl)-N-((4-fluorophenyl) sulfonyl)acrylamide and Tubulin. Molecular Simulation. 2015, 41(4): 356-364.
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