个人简介
2002年毕业于南京大学生物化学系医药生物技术国家重点实验室获博士学位;2003.7-2004.7 赴美国M.D.Anderson cancer center进行博士后研究;2005.10-2005.12及2006.7-2006.12德国MDC分子医学研究所访问学者,主要从事神经系统发育中小RNA的功能研究。江苏省生物化学与分子生物学学会理事,江苏省“青蓝工程”优秀青年骨干教师。
研究领域
miRNAs在神经发育及神经疾病中的功能及作用机制
近期论文
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1.Kong Y, Liang X, Liu L, Zhang D, Wan C, Gan Z, Yuan L. High Throughput Sequencing Identifies MicroRNAs Mediating α-Synuclein Toxicity by Tar geting Neuroactive-Ligand Receptor Interaction Pathway in Early Stage of Drosophila Parkinson's Disease Model. PLoS One.2015 Sep 11;10(9):e013743 2.Peng J, Wang C, Wan C, Zhang D, Li W, Li P, Kong Y,Yuan L. miR-184 is Critical for the motility-related PNS development in Drosophila.Int J Dev Ne urosci. 2015 Aug 22 [Epub ahead of print]. 3.Zheng Y, Yu M, Padmanabhan A, Aster RH, Yuan L, Wen R, Wang D. Critical role of CD4 T cells in PF4/heparin antibody production in mice. Blood.2 015 Mar 12;125(11):1826-9. 4.Wang C, Feng T, Wan Q, Kong Y,Yuan L. miR-124 controls Drosophila behavior and is required for neural development.Int J Dev Neurosci. 2014, 38C: 105-112. 5. Kong Y, Wu J, andYuan L. MicroRNA Expression Analysis of Adult-Onset Drosophila Alzheimer’sDisease Model. Current Alzheimer Research. 2014; 11(9): 882-91. 6. Zheng Y, Yu M, Podd A, Yuan L, Newman DK, Wen R, Arepally G, Wang D. Critical role for mouse marginal zone B cells in PF4/heparin antibody pr oduction. Blood. 2013, 25; 121(17): 3484-92. 7. Li P, Peng J, Hu J, Xu z, Xie W,Yuan L. Localized expression pattern of miR-184 in Drosophila. Molecular Biology Reports. 2011, 38(1): 355-358. 8. Wenwen Lv, Jie Ding, Jiangbo Hu, Chao Wang , Leyi Xu, Ming Fang, Liudi Yuan. A GAL4/UAS Luciferase System to Identify the miRNAs Target m RNAs in Drosophila S2 cells. Molecular Biology Reports. 2009, 36(6): 1627-1631.