Lednev, Igor - University at Albany-SUNY

个人简介

Moscow Institute of Physics and Technology B.S. (1977) Analytical Chemistry Moscow Institute of Physics and Technology M.S. (1980) Analytical chemistry Moscow Institute of Physics and Technology Ph.D. (1983) Physical Chemistry

研究领域

We are analytical chemistry research lab at the University at Albany, located in Albany, NY. We specialize in Raman spectroscopy and advanced chemometrics and use our approach to solve current problems in biochemistry, medicine, and forensics.

近期论文

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Rosario-Alomar, M. F.; Quiñones-Ruiz, T.; Kurouski, D.; Sereda, V.; Ferreira, E. B.; Jesús-Kim, L. D.; Hernández-Rivera, S.; Zagorevski, D. V.; López-Garriga, J.; Lednev, I. K. Hydrogen Sulfide Inhibits Amyloid Formation. J Phys Chem B, 2015, 119, 1265. Kurouski, D.; Handen, J. D.; Dukor, R. K.; Nafie, L. A.; Lednev, I. K. Supramolecular chirality in peptide microcrystals. Chem Comm, 2015, 51, 89. Bueno, J; and Lednev, I.K. Attenuated Total Reflectance-FT-IR Imaging for Rapid and Automated Detection of Gunshot Residue. Anal Chem 2014, 86 (7), 3389-3396. (ACS made press release to highlight this article) Lednev, I.K. Amyloid Fibrils: the Eighth Wonder of the World in Protein Folding and Aggregation. Biophys. J, 106, 7, 1433-1435. McLaughlin, G.; Doty, K.C.; Lednev, I.K. Discrimination of human and animal blood traces via Raman spectroscopy. Forensic Sci Int 2014, 238, 91-95. Kurouski, D.; Lu,X.; Popova, L.; Wan, W.; Shanmugasundaram, M.; Stubbs, G.; Dukor, R.K.; Lednev, I.K. and Nafie, L.A. Is Supramolecular Proto-Filament Chirality the Underlying Cause of Major Morphology Differences in Amyloid Fibrils? J Am Chem Soc 2014, 136 (6), 2302-2312. Kurouski, D.; Deckert-Gaudig, T.; Deckert, V. and Lednev, I.K. Surface Characterization of Insulin Proto-filaments and Fibril Polymorphs Using Tip Enhanced Raman Spectroscopy (TERS). Biophys. J. 2014, 106 (1), 263-271. (Made journal cover) Sikirzhytskaya, A.; Sikirzhytski, V. and Lednev, I.K. Raman spectroscopy coupled with advanced statistics for differentiating menstrual and peripheral blood. J Biophotonics 2014, 7 (1-2), 59-67. (Made journal cover) Kurouski, D.; Sorci, M.; Postiglione, T.; Belfort, G. and Lednev. Detection and Structural Characterization of Insulin Prefibrilar Oligomers Using Surface Enhanced Raman Spectroscopy (SERS). Biotechnology Press 2014, in press. Bueno, J. and Lednev, I.K. Advanced statistical analysis and discrimination of gunshot residue implementing combined Raman and FTIR data. Analyt Methods 2013, 5, 6292-6296. (Made a journal cover). Bueno, J.; Sikirzhytski, V. and Lednev, I.K. Attenuated Total Reflectance-FT-IR Spectroscopy for Gunshot Residue Analysis: Potential for Ammunition Determination. Anal Chem, 2013, 85 (15), 7287–7294. Sikirzhytskaya, A.; Sikirzhytski, V. and Lednev, I.K. Raman spectroscopy coupled with advanced chemometrics for differentiating semen and blood mixtures for forensic purposes. Spectroscopy 2013, 28 (12), 25-29 Bueno, J.; Sikirzhytski, V. and Lednev, I.K. Attenuated Total Reflectace-FT-IR Spectroscopy for Gunshot Residue Analysis: Potential for Ammunition Determination. Anal Chem, 2013, 85 (15), 7287-7294. Kurouski, D.; Luo, H.; Sereda, V.; Robb, R.T. and Lednev, I.K. Deconstruction of stable cross-beta fibrillar structures into toxic and nontoxic products using a mutated archaeal chaperonin. ACS Chem. Biol. 2013, 8, 2095-2101. Kurouski, D.; Kar, K.; Wetzel R.; Dukor, R.K.; Lednev, I.K.; Naﬁe, L.A.; Levels of Supramolecular Chirality of Polyglutamine Aggregates Revealed by Vibrational Circular Dichroism. FEBS Letters 2013, 587 (11), 1638-1643. Burova, T.G.; Ermolenkov, V.V.; Ten, G.N.; Kadrov, D.M.; Nurlygaianova, M.N.; Baranov, V.I. and Lednev, I.K. ionic and Tautomeric Composition of Cytosine in Aqueous Solution: Resonance and Non-Resonance Raman Spectroscopy Study. J Phys Chem 2013, 117, 12734-12748. Bhat, V.; Kurouski, D.; Faridi, M.H.; Olenick, M.B.; Mikles, D.C.; Deegan, B.J.; Seldeen, K.L.; McDonald, C.B.; Gupta, V.: Lednev, I. K.; Farooq, A.. Heat-Induced Fibrillation of BclXL Apoptotic Repressor. Biophys Chem 2013, 179, 12-25. McLaughlin, G.; Sikirzhytski, V.; Lednev, I.K. Circumventing substrate interference in the Raman spectroscopic identiﬁcation of blood stains. Forensic Sci. Int. 2013, 231, 157–166. Kurouski, D., Postiglione, T., Deckert-Gaudig, T., Deckert, V. & Lednev, I. K. Amide I vibrational mode suppression in surface (SERS) and tip (TERS) enhanced Raman spectra of protein specimens. Analyst 2013, 138, 1665-1673. (Made a journal cover). McDonald, C. B.; Bhat, V.; Kurouski, D.; Mikles, D. C.; Deegan, B. J.; Seldeen, K. L.; Lednev, I. K.; Farooq, A.. Structural landscape of the proline-rich domain of Sos1 nucleotide exchange factor. Biophys Chem 2013, 175-176, 54-62.