个人简介
Post-doctoral Associate: University of Maryland, Baltimore County, Baltimore, MD
Ph.D: University of Padua, Padua Italy (1983-1989)
近期论文
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Quinn, R.; Basanta-Sanchez, M.; Rose, R. E.; Fabris, D. “Direct infusion analysis of nucleotide mixtures of very similar or identical elemental composition” J. Mass Spectrom 48 (6), 703–712 (2013), DOI: 10.1002/jms.3207. PuMed PMID: 23722961; PubMed Central PMCID: PMC3767442.
Stephenson, W.; Asare-Okai, P. N.; Chen, A. A.; Keller, S.; Santiago, R.; Tenenbaum, S.; Garcia, A. E.; Fabris, D.; Li, P.T.X. “The essential role of stacking adenines in a two-base-pair RNA kissing complex” J. Amer. Chem. Soc. 135 (15), 5602–5611 (2013), DOI: 10.1021/ja310820h. PubMed PMID: 23517345; PubMed Central PMCID: PMC3664431.
Doria, F.; Nadai, M.; Folini, M.; Scalabrin, M.; Germani, L; Sattin, G.; Mella, M.; Palumbo, M.; Zaffaroni, N.; Fabris, D.; Freccero, M.; and Richter, S. “Targeting Loop Adenines in G-Quadruplex by a Selective Oxirane” Chem. Eur. J. 19, 78-82 (2012), DOI: 10.1002/chem.201203097. PubMed PMID: 23212868; PubMed Central PMCID: PMC3863998.
Fabris, D.; Kellersberger, K.A.; Wilhide, J.A. “Higher-order structure of nucleic acids in the gas-phase: Top-down analysis of base-pairing interactions” Int. J. Mass Spectrom. 312, 155-162 (2012). PubMed PMID: 24027423; PubMed Central PMCID: PMC3767431.
Cantara, W. A.; Crain, P. F.; Rozenski, J.; McCloskey, J. A.; Harris, K. A.; Zhang, X.; Vendeix, F. A. P.; Fabris, D.; Agris, P. F. “The RNA modification database, RNAMDB: 2011 update” Nucleic Acids Res. 39(suppl 1), D195-D201 (2011). DOI: 10.1093/nar/gkq1028. Epub 2010 Nov 10. PubMed PMID: 21071406; PubMed Central PMCID: PMC3013656.
Turner, K. B.; Yi-Brunozzi, H. Y.; Brinston, R. G.; Marino, J. P.; Fabris, D.; and Le Grice, S. F. J. “SHAMS - combining chemical modification of RNA with mass spectrometry to examine polypurine tract-containing RNA/DNA hybrids” RNA 15, 1605-1613 (2009). DOI: 10.1261/rna.1615409. Epub 2009 Jun 17. PubMed PMID: 19535461; PubMed Central PMCID: PMC2714758.
Brinson, R. G.; Turner, K. B.; Yi-Brunozzi, H. Y.; Le Grice, S. F. J.; Fabris, D.; and Marino, J. P. “Probing anomalous structural features in polypurine tract-containing RNA:DNA hybrids with neomycin B” Biochemistry 48, 6988-6997 (2009). DOI: 10.1021/bi900357j. PubMed PMID: 19449839; PubMed Central PMCID: PMC2802280.
Ramos, I., Fernandez E., Fabris D., and Good, T. “Kinetic study of β-amyloid residue accessibility by reductive alkylation and mass spectrometry” Biotech. Bioeng. 104, 181-192 (2009). DOI: 1002/bit.22367. PubMed PMID: 19418563; PubMed Central PMCID: PMC2716430.
Gapeev, A.; Berton, A.; Fabris, D. “Current-controlled nanospray ionization mass spectrometry” J. Am. Soc. Mass Spectrom. 20, 1334-1341 (2009). DOI: 10.1016/j.jasms.2009.03.007. Epub 2009 Mar 14. PubMed PMID: 19359196.
Turner, K. B.; Kohlway, A. S.; Hagan, N. A.; Fabris, D. “Non-covalent probes for the investigation of structure and dynamics of protein-nucleic acid assemblies: the case of NC-mediated dimerization of genomic RNA in HIV-1” invited contribution to Biopolymers 91, 283-296 (2009). DOI: 10.1002/bip.21107. PubMed PMID: 18946871; PubMed Central PMCID: PMC2776628.
Yu, E. T.; Hawkins, A.; Kuntz, I. D.; Rahn, L. A.; Rothfuss, A.; Sale, K; Young, M. M.; Yang, C. L.; Pancerella, C. M.; Fabris, D. “The collaboratory for MS3D: a new cyberinfrastructure for the structural elucidation of biological macromolecules and their assemblies using mass spectrometry-based approaches” J. Proteome Res. 7, 4848-4857 (2008). DOI: 10.1021/pr800443f. Epub 2008 Sep 26. PubMed PMID: 18817429; PubMed Central PMCID: PMC2677910.
Turner, K. B.; Monti, S.; Fabris, D. “Like polarity ion/ion reactions enable the investigation of specific metal interactions in nucleic acids and their non-covalent assemblies” J. Am. Chem. Soc. 30, 13353-13363 (2008). DOI: 10.1021/ja8045734. Epub 2008 Sep 12. PubMed PMID: 18785739; PubMed Central PMCID: PMC2654192.
Legiewicz, M.; Badorrek, C.; Turner, C. B.; Fabris, D.; Hamm, T; Rekosh, D.; Hammarskjöld, M.-L.; Le Grice, S. F. J. “Resistance to RevM10 inhibition reflects a conformational switch in the HIV-1 Rev response element” Proc. Natl. Acad. Sci. U.S.A. 105, 1365-14370 (2008). DOI: 10.1073/pnas.0804461105. Epub 2008 Sep 5. PubMed PMID: 18776047; PubMed Central PMCID: PMC2567145.
Holland, R.; Hawkins, A. E.; Eggler, A.; Mesecar, A.; Fabris, D.; Fishbein, J. C. “Prospective Type 1 and Type 2 Disulfides of Keap1 Protein” Chem. Res. Toxicol. 21, 2051-2060 (2008). DOI: 10.1021/tx800226m. Epub 2008 Aug 26. PubMed PMID: 18729328.
Yu, E. T.; Hawkins, A.; Eaton, J.; Fabris, D. “MS3D structural elucidation of the HIV-1 packaging signal” Proc. Natl. Acad. Sci. U.S.A. 105, 12248-12253 (2008). DOI: 10.1073/pnas.0800509105. Epub 2008 Aug 19. PubMed PMID: 18713870; PubMed Central PMCID: PMC2527897.
Zhang, Q.; Crosland, E.; Fabris, D. “Nested Arg-specific bifunctional crosslinkers for MS-based structural analysis of proteins and protein assemblies” invited contribution to Anal. Chim. Acta 627, 117-128 (2008). DOI: 10.1016/j.aca.2008.05.074. Epub 2008 Jun 5. PubMed PMID: 18790135; PubMed Central PMCID: PMC2677909.
Turner, K. B.; Brinson, R. G.; Yi-Brunozzi, H. Y.; Rausch, J. W.; Miller, J. T. Le Grice, S. F. J.; Marino, J. P.; Fabris, D. “Structural probing of the HIV-1 Polypurine Tract RNA:DNA Hybrid using Classic Nucleic Acid Ligands” Nucleic Acids ResDOI36, 2799-2810 (2008). DOI: 10.1093/nar/gkn129. Epub 2008 Apr 9. PubMed PMID: 18400780; PubMed Central PMCID; PMC2377446.
Stephen, A. G.; Datta, S. A. K.; Worthy, K. M.; Bindu, L.; Fivash, M.J.; Turner, K. B.; Fabris, D.; Rein, A.; Fisher, R.J. “Measuring the binding stoichiometry of HIV-1 Gag to very-low-density oligonucleotide surfaces using plasmon resonance spectroscopy” J. Biomol. Tech. 18, 259-266 (2007). PubMed PMID: 17916799; PubMed Central PMCID: PMC2062552.
Turner, K. B.; Hagan, N. A.; Fabris, D. “Understanding the isomerization of the HIV-1 dimerization initiation domain by the nucleocapsid protein” J. Mol. Biol. 369, 812-828 (2007). Epub 2007 Mar 30. PubMed PMID: 17466332; PubMed Central PMCID: PMC2475603.
Fabris, D.; Chaudhari, P.; Hagan, N. A.; Turner, K. B. “Functional Investigations of Retroviral Protein-RNA Complexes by Nanospray-FTICR Mass Spectrometry” Eur. J. Mass Spectrom. 13, 29-33 (2007). PubMed PMID: 17878535.