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个人简介

Post-doctoral Associate: University of Maryland, Baltimore County, Baltimore, MD Ph.D: University of Padua, Padua Italy (1983-1989)

研究领域

We are a research group in the Departments of Chemistry and Biological Sciences, which is part of The RNA Institute of the University at Albany. We work at the interface of RNA chemistry and biology.

近期论文

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Quinn, R.; Basanta-Sanchez, M.; Rose, R. E.; Fabris, D. “Direct infusion analysis of nucleotide mixtures of very similar or identical elemental composition” J. Mass Spectrom 48 (6), 703–712 (2013), DOI: 10.1002/jms.3207. PuMed PMID: 23722961; PubMed Central PMCID: PMC3767442. Stephenson, W.; Asare-Okai, P. N.; Chen, A. A.; Keller, S.; Santiago, R.; Tenenbaum, S.; Garcia, A. E.; Fabris, D.; Li, P.T.X. “The essential role of stacking adenines in a two-base-pair RNA kissing complex” J. Amer. Chem. Soc. 135 (15), 5602–5611 (2013), DOI: 10.1021/ja310820h. PubMed PMID: 23517345; PubMed Central PMCID: PMC3664431. Doria, F.; Nadai, M.; Folini, M.; Scalabrin, M.; Germani, L; Sattin, G.; Mella, M.; Palumbo, M.; Zaffaroni, N.; Fabris, D.; Freccero, M.; and Richter, S. “Targeting Loop Adenines in G-Quadruplex by a Selective Oxirane” Chem. Eur. J. 19, 78-82 (2012), DOI: 10.1002/chem.201203097. PubMed PMID: 23212868; PubMed Central PMCID: PMC3863998. Fabris, D.; Kellersberger, K.A.; Wilhide, J.A. “Higher-order structure of nucleic acids in the gas-phase: Top-down analysis of base-pairing interactions” Int. J. Mass Spectrom. 312, 155-162 (2012). PubMed PMID: 24027423; PubMed Central PMCID: PMC3767431. Cantara, W. A.; Crain, P. F.; Rozenski, J.; McCloskey, J. A.; Harris, K. A.; Zhang, X.; Vendeix, F. A. P.; Fabris, D.; Agris, P. F. “The RNA modification database, RNAMDB: 2011 update” Nucleic Acids Res. 39(suppl 1), D195-D201 (2011). DOI: 10.1093/nar/gkq1028. Epub 2010 Nov 10. PubMed PMID: 21071406; PubMed Central PMCID: PMC3013656. Turner, K. B.; Yi-Brunozzi, H. Y.; Brinston, R. G.; Marino, J. P.; Fabris, D.; and Le Grice, S. F. J. “SHAMS - combining chemical modification of RNA with mass spectrometry to examine polypurine tract-containing RNA/DNA hybrids” RNA 15, 1605-1613 (2009). DOI: 10.1261/rna.1615409. Epub 2009 Jun 17. PubMed PMID: 19535461; PubMed Central PMCID: PMC2714758. Brinson, R. G.; Turner, K. B.; Yi-Brunozzi, H. Y.; Le Grice, S. F. J.; Fabris, D.; and Marino, J. P. “Probing anomalous structural features in polypurine tract-containing RNA:DNA hybrids with neomycin B” Biochemistry 48, 6988-6997 (2009). DOI: 10.1021/bi900357j. PubMed PMID: 19449839; PubMed Central PMCID: PMC2802280. Ramos, I., Fernandez E., Fabris D., and Good, T. “Kinetic study of β-amyloid residue accessibility by reductive alkylation and mass spectrometry” Biotech. Bioeng. 104, 181-192 (2009). DOI: 1002/bit.22367. PubMed PMID: 19418563; PubMed Central PMCID: PMC2716430. Gapeev, A.; Berton, A.; Fabris, D. “Current-controlled nanospray ionization mass spectrometry” J. Am. Soc. Mass Spectrom. 20, 1334-1341 (2009). DOI: 10.1016/j.jasms.2009.03.007. Epub 2009 Mar 14. PubMed PMID: 19359196. Turner, K. B.; Kohlway, A. S.; Hagan, N. A.; Fabris, D. “Non-covalent probes for the investigation of structure and dynamics of protein-nucleic acid assemblies: the case of NC-mediated dimerization of genomic RNA in HIV-1” invited contribution to Biopolymers 91, 283-296 (2009). DOI: 10.1002/bip.21107. PubMed PMID: 18946871; PubMed Central PMCID: PMC2776628. Yu, E. T.; Hawkins, A.; Kuntz, I. D.; Rahn, L. A.; Rothfuss, A.; Sale, K; Young, M. M.; Yang, C. L.; Pancerella, C. M.; Fabris, D. “The collaboratory for MS3D: a new cyberinfrastructure for the structural elucidation of biological macromolecules and their assemblies using mass spectrometry-based approaches” J. Proteome Res. 7, 4848-4857 (2008). DOI: 10.1021/pr800443f. Epub 2008 Sep 26. PubMed PMID: 18817429; PubMed Central PMCID: PMC2677910. Turner, K. B.; Monti, S.; Fabris, D. “Like polarity ion/ion reactions enable the investigation of specific metal interactions in nucleic acids and their non-covalent assemblies” J. Am. Chem. Soc. 30, 13353-13363 (2008). DOI: 10.1021/ja8045734. Epub 2008 Sep 12. PubMed PMID: 18785739; PubMed Central PMCID: PMC2654192. Legiewicz, M.; Badorrek, C.; Turner, C. B.; Fabris, D.; Hamm, T; Rekosh, D.; Hammarskjöld, M.-L.; Le Grice, S. F. J. “Resistance to RevM10 inhibition reflects a conformational switch in the HIV-1 Rev response element” Proc. Natl. Acad. Sci. U.S.A. 105, 1365-14370 (2008). DOI: 10.1073/pnas.0804461105. Epub 2008 Sep 5. PubMed PMID: 18776047; PubMed Central PMCID: PMC2567145. Holland, R.; Hawkins, A. E.; Eggler, A.; Mesecar, A.; Fabris, D.; Fishbein, J. C. “Prospective Type 1 and Type 2 Disulfides of Keap1 Protein” Chem. Res. Toxicol. 21, 2051-2060 (2008). DOI: 10.1021/tx800226m. Epub 2008 Aug 26. PubMed PMID: 18729328. Yu, E. T.; Hawkins, A.; Eaton, J.; Fabris, D. “MS3D structural elucidation of the HIV-1 packaging signal” Proc. Natl. Acad. Sci. U.S.A. 105, 12248-12253 (2008). DOI: 10.1073/pnas.0800509105. Epub 2008 Aug 19. PubMed PMID: 18713870; PubMed Central PMCID: PMC2527897. Zhang, Q.; Crosland, E.; Fabris, D. “Nested Arg-specific bifunctional crosslinkers for MS-based structural analysis of proteins and protein assemblies” invited contribution to Anal. Chim. Acta 627, 117-128 (2008). DOI: 10.1016/j.aca.2008.05.074. Epub 2008 Jun 5. PubMed PMID: 18790135; PubMed Central PMCID: PMC2677909. Turner, K. B.; Brinson, R. G.; Yi-Brunozzi, H. Y.; Rausch, J. W.; Miller, J. T. Le Grice, S. F. J.; Marino, J. P.; Fabris, D. “Structural probing of the HIV-1 Polypurine Tract RNA:DNA Hybrid using Classic Nucleic Acid Ligands” Nucleic Acids ResDOI36, 2799-2810 (2008). DOI: 10.1093/nar/gkn129. Epub 2008 Apr 9. PubMed PMID: 18400780; PubMed Central PMCID; PMC2377446. Stephen, A. G.; Datta, S. A. K.; Worthy, K. M.; Bindu, L.; Fivash, M.J.; Turner, K. B.; Fabris, D.; Rein, A.; Fisher, R.J. “Measuring the binding stoichiometry of HIV-1 Gag to very-low-density oligonucleotide surfaces using plasmon resonance spectroscopy” J. Biomol. Tech. 18, 259-266 (2007). PubMed PMID: 17916799; PubMed Central PMCID: PMC2062552. Turner, K. B.; Hagan, N. A.; Fabris, D. “Understanding the isomerization of the HIV-1 dimerization initiation domain by the nucleocapsid protein” J. Mol. Biol. 369, 812-828 (2007). Epub 2007 Mar 30. PubMed PMID: 17466332; PubMed Central PMCID: PMC2475603. Fabris, D.; Chaudhari, P.; Hagan, N. A.; Turner, K. B. “Functional Investigations of Retroviral Protein-RNA Complexes by Nanospray-FTICR Mass Spectrometry” Eur. J. Mass Spectrom. 13, 29-33 (2007). PubMed PMID: 17878535.

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