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个人简介

1994年毕业于大连医科大学检验系,获医学学士学位;1997年获大连医科大学生物化学专业医学硕士学位;2009年获德国海德堡大学寄生虫学博士学位,博士期间主要从事新一代抗疟疾药物研发工作。博士毕业后在德国从事药物研发工作,2012年回国入职大连医科大学工作。2012年至今,主持横向课题研究9项,以通讯和第一作者发表SCI论文3篇,指导多项辽宁省大学生挑战杯科研获奖项目。

研究领域

1. 抗疟疾药物研发 2. 抗肿瘤药物研发 3. 抗炎症药物研发

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Stefano Pegoraro, Maëlle Duffey, Thomas D Otto, Yulin Wang, Roman Rösemann, Roland Baumgartner, Stefanie K Fehler, Leonardo Lucantoni, Vicky M Avery, Alicia Moreno-Sabater, Dominique Mazier, Henri J Vial, Stefan Strobl, Cecilia P Sanchez, Michael Lanzera. SC83288 is a clinical development candidate for the treatment of severe malaria. Nat Commun. 2017, 8: 14193. (影响因子:11.3) 2. Yuming Sun, Yang Yang, Xiaohui Li, Mingming Chang, Dong Li, Tingting Pu, Xue Ding, Qing Wang, Yulin Wang. Effect of glycyrrhizic acid on the oral absorption of paeoniflorin in rats in vivo. RSC Advances. 2016, 6: 46925-46928. (Corresponding author,通讯作者,影响因子:3.8) 3. 刘天齐, 于婧, 朱梦影, 张霖惠, 王玉林*. BH3模拟物类抗肿瘤药物研发进展. 中南药学, 2016, (2):179-182.(通讯作者) 4. 孙玉明, 李英, 王月月, 张华, 王玉林*. 盐酸特拉唑嗪降解产物的结构鉴定. 色谱, 2016, (5):490-497. (通讯作者) 5. 孙玉明, 李英, 杨琳, 王月月, 王玉林*. 盐酸特拉唑嗪在大鼠体内的排泄研究. 中南药学, 2016, (4):354-357.(通讯作者) 6. Wang F, Liu Z, Wang J, Tao J, Gong P, Bao X, Zhao Y, Wang Y. The interaction of 4-thiazolidinone derivatives containing indolin-2-one moiety with P-glycoprotein studied using K562 cell lines. Eur J Med Chem. 2015, 101:126-132. (通讯作者,影响因子:3.5) 7. 易翠林,时京杰,包雪,王玉林*.KA2012MBL复合提取液体外抗肿瘤活性评价及相关机制研究.大连医科大学学报. 2014,(1):18-22。 (通讯作者) 8. 易翠林,时京杰,包雪,王玉林*.KA2012HRS复合提取液对K562细胞凋亡的诱导作用和细胞周期的阻滞作用相关研究. 辽宁师范大学学报(自然科学版),2014,(4):541-546。(通讯作者) 9. Plaimas K1, Wang Y, Rotimi SO, Olasehinde G, Fatumo S, Lanzer M, Adebiyi E, König R.Computational and experimental analysis identified 6-diazo-5-oxonorleucine as a potential agent for treating infection by Plasmodium falciparum. Infect Genet Evol. 2013,20:389-95. (并列第一作者,影响因子:3.8) 10. Heinrich S, Altenkämper M, Bechem B, Perruchon J, Ortmann R, Dahse HM, Wang Y, Lanzer M, Schlitzer M. 2-Acylamino-5-chlorobenzophenones with enhanced selectivity towards malaria parasites. Eur J Med Chem. 2011, 46(4):1331-42 (影响因子:3.3) 11. Wenzel NI, Chavain N, Wang Y, Friebolin W, Maes L, Pradines B, Lanzer M, Yardley V, Brun R, Herold-Mende C, Biot C, Tóth K, Davioud-Charvet E. Antimalarial versus cytotoxic properties of dual drugs derived from 4- aminoquinolines and Mannich bases: interaction with DNA. J Med Chem. 2010, 53(8):3214-26. (影响因子:4.9) 12. Altenkämper M, Bechem B, Perruchon J, Heinrich S, Mädel A, Ortmann R, Dahse HM, Freunscht E, Wang Y, Rath J, Stich A, Hitzler M, Chiba P, Lanzer M, Schlitzer M. Antimalarial and antitrypanosomal activity of a series of amide and sulfonamide derivatives of a 2,5- diaminobenzophenone. Bioorg Med Chem. 2009, 17(22):7690-7. (影响因子:2.8) 13. Yulin Wang, DaCheng Hao, Wilfred D. Stein and Ling Yang. A kinetic study of Rhodamine123 pumping by P-glycoprotein. Biochimica et Biophysica Acta (BBA)-Biomembranes. 2006,1758(10) 1671-1676 (影响因子:3.9) 14. Quanbin Han, Ling Yang, Yong Liu, Yulin Wang, Chunfeng Qiao, Jingzheng Song, Lijia Xu, Dajian Yang, Shilin Chen, Hongxi Xu . Gambogic acid and epigambogic acid, C-2 epimers with novel anticancer effects from Garcinia hanburyi. Planta. Med. 2006, 72(3):281-4. (影响因子:1.7) 15. Hua Xiao, Xin Li, Hanfa Zou, Ling Yang, Yanqin Yang, Yulin Wang, Hailin Wang, X. Chris Le. Immunoassay of P-glycoprotein on single cell by capillary electrophoresis with laser induced fluorescence detection. Analytica Chimica Acta.2006, 556(2): 340-346 (影响因子:3.8) 16. Xiao H, Li X, Zou H, Yang L, Yulin Wang, Wang H, Le XC. CE-LIF coupled with flow cytometry for high-throughput quantitation of fluorophores in single intact cells. Electrophoresis. 2006, 27(17):3452-9 (影响因子:3.6).

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