研究领域

polymer chemistry biomaterials degradable polymers colloidal crystals glycopolymers

Professor Zhu’s group focuses on the synthesis, characterization and development of new polymeric materials, including hydrogels, degradable polymers, shape-memory materials and nano- and microparticles, for biomedical and industrial applications.

近期论文

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J. Xu, S. Strandman, X. X. Zhu, J. Barralet and M. Cerruti*, "Genipin-crosslinked catechol-chitosan mucoadhesive hydrogels for buccal drug delivery", Biomaterials, 37, 395–404, 2015. DOI: 10.1016/j.biomaterials.2014.10.024. Q. Du, Y. Guan, X.X. Zhu, Y. Zhang, "Swelling-induced surface instability patterns guided by pre-introduced structures", Soft Matter, 11, 1937-1944, 2015. DOI: 10.1039/C4SM02584A. J. Hou, Chong Li, Y. Guan, Y. Zhang, X. X. Zhu, "Enzymatically crosslinked alginate hydrogels with improved adhesion properties", Polym. Chem., in press, 2015. DOI: 10.1039/C4PY01757A. S. Strandman, X.X. Zhu*, "Thermo-responsive block copolymers with multiple phase transition temperatures in aqueous solutions", Prog. Polym. Sci., 42, 154–176, 2015. DOI:10.1016/j.progpolymsci.2014.10.008. Y.G. Jia, X.X. Zhu*, "Self-Healing Supramolecular Hydrogel Made of Polymers Bearing Cholic Acid and ß-Cyclodextrin Pendants", Chem. Mater., 27, 387-393, 2015. DOI: 10.1021/cm5041584. M. Verrapandian, X. X. Zhu*, S. Giasson*, "Chitosan-modified silver@ruthenium hybrid nanoparticles: evaluation of physico-chemical properties and bio-affinity with sialic acid", J. Mater. Chem. B, 3, 665-672. 2015. DOI: 10.1039/C4TB01475H. S. Strandman, X. X. Zhu*, "Biodegradable shape memory polymers for biomedical applications", Chapter 11, in “Shape Memory Polymers for Biomedical Applications”, Elsevier, book in press, April 2015. Y.G. Jia, X.X. Zhu*, "Thermoresponsiveness of Copolymers Bearing Cholic Acid Pendants Induced by Complexation with ß-Cyclodextrin", Langmuir, 30, 11770–11775, 2014. DOI: 10.1021/la5030873. M. Savoji, S. Strandman, X.X. Zhu*, "Invertible vesicles and micelles formed by dually-responsive diblock random copolymers in aqueous solutions", Soft Matter, 10, 5886-5893, 2014. DOI: 10.1039/C4SM01049C. Y. Shao, Y. Jia, C. Shi, J. Luo, X.X. Zhu*, "Block and random copolymers bearing cholic acid and oligo(ethylene glycol) pendant groups: Aggregation, thermosensitivity and drug loading", Biomacromolecules, 15, 1837-1844, 2014. DOI: 10.1021/bm5002262. Y. Jia, X.X. Zhu*, "Complex thermoresponsive behavior of diblock polyacrylamides", Polym. Chem., 5, 4358-4364, 2014. DOI: 10.1039/C4PY00036F. N. Huang, Y. Guan, X.X. Zhu, Y.J. Zhang, "Swelling Kinetics of Microgels Embedded in a Polyacrylamide Hydrogel Matrix", ChemPhysChem, 15, 1785-1792, 2014. DOI: 10.1002/cphc.201400027. Z.Q. Zhao, J.J. Gu, Y.N. Zhao, Y. Guan, X.X. Zhu, Y.J. Zhang, "Hydrogel Thin Film with Swelling-Induced Wrinkling Patterns for High-Throughput Generation of Multicellular Spheroids", Biomacromolecules, 15, 3306-3312, 2014. DOI: 10.1021/bm500722g. Q. Han, C. Li, Y. Guan, X. X. Zhu, Y. Zhang, "Swelling-induced surface instability of a hydrogen-bonded LBL film and its self-healing", Polymer, 55, 2197-2204, 2014. DOI: 10.1016/j.polymer.2014.03.015. F. Le Dévédec, S. Strandman, P. Hildgen, G. Leclair, X. X. Zhu*, "PEGylated bile acids for use in drug delivery systems: Enhanced solubility and bioavailability of Itraconazole", Mol. Pharmaceutics, 10, 3057-3066, 2013. DOI: 10.1021/mp400117m. S. Strandman, I-H. Tsai, R. Lortie, X. X. Zhu*, "Ring-opening polymerization of bile acid macrocycles by Candida antarctica lipase B", Polym. Chem., 4, 4312-4316, 2013. DOI:10.1039/C3PY00651D. M. T. Savoji, S. Strandman, X. X. Zhu*, "Switchable Vesicles Formed by Diblock Random Copolymers with Tunable pH- and Thermo-Responsiveness", Langmuir, 29, 6823–6832, 2013. DOI: 10.1021/la4009625. F. Le Dévédec, S. Strandman, W. E. Baille, X. X. Zhu*, "Functional star block copolymers with a cholane core: Thermo-responsiveness and aggregation behavior", Polymer, 54, 3898–3903, 2013. DOI: 10.1016/j.polymer.2013.05.036. W. Zhang, J. Song, W. Liao, Y. Guan, Y. Zhang, X. X. Zhu, "In situ generation of fluorescent silver nanoclusters in layer-by-layer assembled films", J. Mater. Chem. C, 1, 2036-2043, 2013. DOI: 10.1039/C3TC00415E. W. Song, Y. Guan, Y. Zhang*, X. X. Zhu, "Mutual interaction between embedded microgel particles and the surrounding hydrogel matrix", Soft Matter, 9, 2629 - 2636, 2013. DOI: 10.1039/C2SM27534A.