研究领域

polymer chemistry self-assembly of ampiphilic materials colloid analysis methods therapeutic applications of nanoparticles

The research conducted by Professor Winnik and her group is aimed at designing new functional nanometric objects. The group is collaborating internationally to study the self-assembly of hydrosoluble or amphipilic polymers in solution and at interfaces, with a view on their biomedical and diagnostic applications

近期论文

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J. An, X. Liu, P. Linse, A. Dedinaite, F. M. Winnik and P. M. Claesson, Tethered Poly(2-isopropyl-2-oxazoline) Chains: Temperature Effects on Layer Structure and Interactions Probed by AFM Experiments and Modeling, Langmuir 2015, 31(10), 3039-3048. A. Moquin, K. D. Neibert, D. Maysinger and Françoise M. Winnik, Quantum dot agglomerates in biological media and their characterization by asymmetrical flow field-flow fractionation, European Journal of Pharmaceutics and Biopharmaceutics 2015, 89, 290-299 B. Qi, P. Kujawa, S. Toita, G. Beaume and F. M. Winnik, Phosphorylcholine-Modified Chitosan Films as Effective Promoters of Cell Aggregation: Correlation Between the Films Properties and Cellular Response, Macromolecular Bioscience 2015 ASAP DOI: 10.1002/mabi.201400439. R. Takahashi, X.P. Qiu, N. Xue, T. Sato, K. Terao and F. M. Winnik, Self-Association of the Thermosensitive Block Copolymer Poly(2-isopropyl-2-oxazoline)-b-poly(N-isopropylacrylamide) in Water-Methanol Mixtures, Macromolecules, 2014, 47 (19), 6900–6910. D. Ma, N. Martin C. Tribet and F. M. Winnik, Quantitative characterization by asymmetrical flow field-flow fractionation of IgG thermal aggregation with and without polymer protective agents, Analytical and Bioanalytical Chemistry , 2014, 406(29), pp 7539-7547. N. Martin, D. Ma, A. herbet, D. Boquet, F. M. Winnik and C. Tribet, Prevention of Thermally Induced Aggregation of IgG Antibodies by Noncovalent Interaction with Poly(acrylate) Derivatives, Biomacromolecules , 2014, 15(8), 2952-2962. N. Morimoto, Y. Sasaki, K. Mitsunushi, E. Korchagina, T. Wazama, X.P. Qiu, S. M. Nomura, M. Suzuki and F. M. Winnik, Temperature-responsive telechelic dipalmitoylglyceryl poly(N-isopropylacrylamide) vesicles: real-time morphology observation in aqueous suspension and in the presence of giant liposomes, Chemical Communications , 2014, 50(61), 8350-8352. T. Borke, F. M. Winnik, H. Tenhu and S. Hietala, Optimized triazine-mediated amidation for efficient and controlled functionalization of hyaluronic acid, Carbohydrate Polymers , 2015, 116, 42-50. X. P. Qiu, E. Korchagina, J. Rolland and F. M. Winnik, Synthesis of a poly(N-isopropylacrylamide) charm bracelet decorated with a photomobile α-cyclodextrin charm, Polymer Chemistry, 2014, 5, 3656-3665. Junxue An, Andra Dėdinaitė, Francoise M. Winnik, Xing-Ping Qiu and Per M. Claesson, Temperature-Dependent Adsorption and Adsorption Hysteresis of a Thermoresponsive Diblock Copolymer, Langmuir, 2014, 30 (15), 4333–4341. Y.-T. R. Lau, M. Yamaguchi, X. Li, Y. Bando, D.Golberg and F. M. Winnik, Length Fractionation of Boron Nitride Nanotubes using creamed Oil-in-Water emulsions , Langmuir, 2013, 30 (7), 1735–1740. Description. P. Kujawa and F. M. Winnik, Innovation in Nanomedicine through materials nanoarchitectonics , Langmuir, 2013, 29 (24), 7354–7361. Description. E. Korchagina, X.P. Qiu and F. M. Winnik, Effect of heating rate on the pathway for vesicle formation in salt free aqueous solutions of thermosensitive cationic diblock copolymers , Macromolecules, 2013, 46(6), 2341-2351. Description. F. M. Winnik and D. Maysinger, Quantum dot toxicity and ways to reduce it, Acc. Chem. Res., Web ed, 09-07-2012 DOI 10.1021/ar3000585. Description. Z. Miao, P. Kujawa, Y.-T. R. Lau, S. Toita, B. Qi, J. Nakanishi, I. Cloutier, J.F. Tanguay, F. M. Winnik, Tuning the properties and functions of 17β-estradiol-polysaccharide conjugates in thin films: impact of sample history , Biomacromolecules , 2012, (12), 4098–4108. Description. A. Shimoda, S.-I. Sawada, A. Kano, A. Maruyama, A. Moquin, F. M. Winnik, A. Akiyoshi, Dual crosslinked hydrogel nanoparticles by nanogel bottom-up method for sustained-release delivery, Coll. Surf, B-Biointerface , 2012, 99 SI 38-44. Description. H. Basit, K.S. Sharma, A. vn er Heyden, C. Gindran, C. Breytin, P. Dummy, F.M. Winnik, P. Labbe, Amphipol mediated surface immobilization of FhuA: a platform for label-free detection of the bacteriophage protein pb5, Chem. Comm., 2012, 48, 6037-6039. Description. M. Gong, Y. Duang, Y.-B. Wang, S. Yang, F. M. Winnik and Y.-K. Gong, Cell membrane mimetic films immobilized bysynergistic grafting and crosslinking, Soft Matter, 2013, 9, 4501-4508. J. C. Fernandes, X. P. Qiu, F. M. Winnik, M. Benderdour, X. Zhang, K. Dai, Q. Shi, Low-molecular weight chitosan conjugated with folate for siRNA delivery in vitro: optimization studies, Internat. J. Nanomedicine, 2012:7 5833-5845. C. Tolg, S.R. Hamilton, E. Zalinska, L. McCulloch, R.Amin, N. Akentieva, F. M. Winnik, R. Savani. D. J.Bagli, L. G. Luyt, M. K. Cowman, J. B. McCarthy, E. A. Turley, A RHAMM mimetic peptide blocks hyaluronan:RHAMM interactions and reduces inflammation and fibrogenesis of excisional skin wounds, Am. J. Path, 2012, 181 (4) 1250-1270.