个人简介
张传领,助理研究员。获得国家自然基金委面上、青年基金、教育部博士点基金(新教师类)和北京市自然科学基金等多项资助。在Biomaterials, Sci. Rep. 等杂志发表多篇SCI论文,并申请多项专利
研究领域
基于基因密码子扩展技术建立非天然氨基酸定点标记蛋白质的新方法,进而利用该方法在病毒载体修饰、新型蛋白药物、生物大分子药物作用机制及相关生物技术方面进行拓展应用研究。
近期论文
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1. Chuanling Zhang* (first and co-corresponding author),Xueying Zhou, Tianzhuo Yao, Zhenyu Tian and Demin Zhou*. Precision Fluorescent Labeling of an Adeno-Associated Virus Vector to Monitor the Viral Infection Pathway. Biotechnology Journal . 2017, Dec.27(accepted)
2. Tianzhuo Yao#, Xueying Zhou#, Chuanling Zhang* (co-corresponding), Xiaojuan Yu, Zhenyu Tian, Lihe Zhang, Demin Zhou*. Site-Specific PEGylated Adeno-Associated Viruses with Increased Serum Stability and Reduced Immunogenicity. Molecules . 2017 Jul 11;22(7).
3. Chuanling Zhang #*(co-first and co-corresponding author),Jiaqi Lu #, HuizhongSu, Jing Yang, Demin Zhou *.Fatty acid synthase cooperates with protrudin to facilitate membrane outgrowth of cellular protrusions. Sci Rep. 2017 Apr 21;7:46569.
4. Chuanling Zhang, Tianzhuo Yao, Yongxiang Zheng, Zhongjun Li, Qiang Zhang, Lihe Zhang, Demin Zhou*. Development of next generation adeno-associated viral vectors capable of selective tropism and efficient gene delivery. Biomaterials. 2016 Feb;80:134-145.
5. Chuanling Zhang, Tianzhuo Yao, Yongxiang Zheng, Zhongjun Li, Lihe Zhang, Demin Zhou* Data on interaction between adeno-associated virus and U87 cell via cRGD chemical modification. Data Brief. 2016 Feb 10;7:77-80.
6. Chuanling Zhang, Dan Li, Yan Ma, Jinting Yan, Baiqing Yang, Peng Li, Aiping Yu, Cailing Lu*, Xu Ma*.Role of spastin and protrudin in neurite outgrowth. J Cell Biochem. 2012,113 (7): 2296-2307。
7. Chuanling Zhang #,Chunmei Liu#, Dan Li, Nan Yao, Xiaohua Yuan, Aiping Yu, Cailing* Lu, Xu Ma*. Intracellular redox imbalance and extracellular amino acid metabolic abnormality contribute to arsenic-induced developmental retardation in mouse preimplantation embryos. J Cell Physiol, 2010, 222(2): 444-455.
8. Chuanling Zhang, Aiping Yu, Bin Yuan, Chunna Dong, Hongyang Yu, Lisheng Wang, Chutse Wu*. Construction and functional evaluation of hirudin derivatives with low bleeding risk. Thromb Haemost, 2008, 99 (2): 324-330.