个人简介
京大学药学院药理学博士,讲师。2010.10-2011.10作为联培博士生赴日本东京大学留学,2017.1-2018.8赴美国威斯康星大学麦迪逊分校访学。主持国家自然科学基金(青年基金)1项和教育部博士点基金1项,参与多个项目研究。
研究领域
主要从事神经退行性疾病和神经发育疾病的发生机制,以及基于靶点的中枢神经系统新药药效学及机制研究
近期论文
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[1] Y. Sun, Y. Gao, J.J. Tidei, M. Shen, J.T. Hoang, D. Wagner, X. Zhao, Loss of MeCP2 in immature neurons leads to impaired network integration, Hum Mol Genet, DOI 10.1093/hmg/ddy338(2018).
[2] Y. Wang#, Y. Sun#*, X. Zhao, R. Yuan, H. Jiang*, X. Pu*, Downregulation of DJ-1 Fails to Protect Mitochondrial Complex I Subunit NDUFS3 in the Testes and Contributes to the Asthenozoospermia, Mediators Inflamm, 2018 (2018) 6136075.
[3] Y. Sun, Y. Wang, X. Zhao, X. Pu, Nuclear translocation of DJ-1 protects adult neuronal stem cells in an MPTP mouse model of Parkinson's disease, Neuroreport, 29 (2018) 301-307.
[4] Y. Sun, W.J. Zhang, X. Zhao, R.P. Yuan, H. Jiang, X.P. Pu, PARK7 protein translocating into spermatozoa mitochondria in Chinese asthenozoospermia, Reproduction, 148 (2014) 249-257.
[5] Y. Sun, H. Norimoto, X.P. Pu, N. Matsuki, Y. Ikegaya, Cannabinoid receptor activation disrupts the internal structure of hippocampal sharp wave-ripple complexes, J Pharmacol Sci, 118 (2012) 288-294.
[6] S. Li#, Y. Sun#, X. Zhao, X.P. Pu, Expression of the Parkinson's disease protein DJ-1 during the differentiation of neural stem cells, Brain Res, 1468 (2012) 84-93.
[7] Y. Wang, Y. Sun*, X. Pu*, Endogenous antioxidant DJ-1: A potential target for asthenozoospermia, Journal of Chinese Pharmaceutical Sciences, 2017, 26 (10): 697-708.
[8] Y. Yang, Y. Sun*, X. Zhao, X. Zheng, X. Pu, Effects of Salvia miltiorrhiza injectional powder on the development of liver fibrosis initiated by dimethylnitrosamine in rats, Journal of Chinese Pharmaceutical Sciences, 2015, 24 (01): 54-62.