个人简介
1993年9月-1997年7月 在北京医科大学药学院药学专业学习，获理学学士学位
1997年8月-1999年8月 在北京市石景山医院药剂科工作
1999年9月-2005年6月 在北京大学药学院生药学专业学习，获理学博士学位
2005年12月-2007年3月 日本金泽大学药学部， COE研究员
2007年5月-2009年11月 北京大学，博士后
2009年11月-2017年7月 北京大学药学院，助理研究员。
2017年8月-至今 北京大学药学院，副教授
2016年2月-至今 日本金泽大学，合作教授
研究领域
1. 中药及中药复方药效物质基础研究
2. 天然药物的体内过程研究
近期论文
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1. Li-Man MA#, Feng XU#, Jing-Zhe WANG, Ming-Ying SHANG*？, Guang-Xue LIU, Shao-Qing CAI. In vivo metabolism of 8,2'-diprenylquercetin 3-methyl ether and distribution of its metabolites in rats by HPLC-ESI-IT-TOF-MSn. Fitoterapia. 2019 Jun 1:104191. doi: 10.1016/j.fitote.2019.104191.
2. Hong-Yan WANG, Teng LI, Rui JI, Feng XU*, Guang-Xue LIU, Yao-Li LI, Ming-Ying SHANG*, Shao-Qing CAI. Metabolites of medicarpin and their distributions in rats. Molecules. 2019, 24(10), 1966; http://dx.doi.org/10.3390/molecules24101966
3. Wei-Wei ZHANG#, Feng XU#, Ding WANG, Jia YE*, Shao-Qing CAI*. Buyang Huanwu Decoction ameliorates ischemic stroke by modulating multiple targets with multiple components: in vitro evidence.Chinese Journal of Natural Medicines. 2018, 16(3): 194-202.
4. Jing-Jing XU, Feng XU*, Shu-Jie SHEN, Teng LI, Yi-Fan ZHANG, Ming-Ying SHANG, Yao-Li LI, Guang-Xue LIU, Xuan WANG, Shao-Qing CAI*. Holistic and dynamic metabolic alterations of traditional Chinese medicine syndrome in a toxic heat and blood stasis syndrome rat model. RSC Advances. 2017, 7(89): 56471-56483.
5. Hong-Fu LI, Feng XU*, Ping YANG, Guang-Xue LIU, Ming-Ying SHANG, Xuan WANG, Jun YIN, Shao-Qing CAI*. Systematic screening and characterization of prototype constituents and metabolites of total astragalosides using HPLC-ESI-IT-TOF-MSn after oral administration to rats. Journal of Pharmaceutical and Biomedical Analysis. 2017, 142: 102-112.
6. Ping YANG, Feng XU*, Hong-Fu LI, Yi WANG, Feng-Chun LI, Ming-Ying SHANG, Guang-Xue LIU, Xuan WANG, Shao-Qing CAI*. Detection of 191 Taxifolin Metabolites and Their Distribution in Rats Using HPLC-ESI-IT-TOF-MSn. Molecules. 2016, 21(9), 1209; doi:10.3390/molecules21091209.
7. Feng XU, Dian-Peng LI*, Zhen-Cong HUANG, Feng-Lai LU, Lei WANG, Yong-Lin HUANG, Ru-Feng WANG, Guang-Xue LIU, Ming-Ying SHANG, Shao-Qing CAI*. Exploring in vitro, in vivo metabolism of mogroside V and distribution of its metabolites in rats by HPLC-ESI-IT-TOF-MSn. Journal of Pharmaceutical and Biomedical Analysis. 2015, 115: 418-430.
8. Chen LI#, Feng XU#, De-Mei XIE, Yu JING, Ming-Ying SHANG, Guang-Xue LIU, Xuan WANG and Shao-Qing CAI*. Identification of absorbed constituents in the rabbit plasma and cerebrospinal fluid after intranasal administration of Asari Radix et Rhizoma by HS-SPME-GC-MS and HPLC-APCI-IT-TOF-MSn. Molecules. 2014, 19(4): 4857-4879.
9. 徐风, 杨东辉, 尚明英, 王璇, 蔡少青*. 中药药效物质的“显效形式”、“叠加作用”和“毒性分散效应”——由中药体内代谢研究引发的思考. 世界科学技术-中医药现代化. 2014, 16(4): 688-703.
10. Jing LIANG#, Feng XU#, Ya-Zhou ZHANG, Shuai HUANG, Xin-Yu ZANG, Xin ZHAO, Lei ZHANG, Ming-Ying SHANG, Dong-Hui YANG, Xuan WANG, Shao-Qing CAI*. The profiling and identification of the absorbed constituents and metabolites of Paeoniae Radix Rubra decoction in rat plasma and urine by the HPLC-DAD-ESI-IT-TOF-MSn technique: A novel strategy for systematic screening and identification of absorbed constituents and metabolites from traditional Chinese medicines. Journal of Pharmaceutical and Biomedical Analysis. 2013, 83: 108-121.
11. Ya-Zhou ZHANG#, Feng XU#, Jing DONG, Jing LIANG, Yuki HASHI, Ming-Ying SHANG, Dong-Hui YANG, Xuan WANG, Shao-Qing CAI*. Profiling and identification of the metabolites of calycosin in rat hepatic 9000 × g supernatant incubation system and the metabolites of calycosin-7-O-β-D-glucoside in rat urine by HPLC-DAD-ESI-IT-TOF-MSn technique. Journal of Pharmaceutical and Biomedical Analysis. 2012, 70(11): 425-439.
12. Feng XU, Yue ZHANG, Sheng-Yuan XIAO, Xiao-Wei LU, Dong-Hui YANG, Xiao-Da YANG, Chang-Ling LI, Ming-Ying SHANG, Peng-Fei TU, Shao-Qing CAI*. Absorption and metabolism of Astragali Radix decoction: in silico, in vitro, and a case study in vivo. Drug Metabolism and Disposition. 2006, 34(6): 913-924.
13. 徐风, 杨东辉, 张悦, 陆晓薇, 李长龄, 杨晓达, 尚明英, 蔡少青*. 以补阳还五汤为例探讨中药复方药效物质基础研究方法. 第三届国际传统医药大会. 2004年11月13-15日, 北京.
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