个人简介
已在Chem. Commun.，J. Org. Chem.,Org. Biomol. Chem.,Bioorg. Med. Chem. Lett., Tetrahedron,等国际杂志发表文章四十余篇，申请多项专利。主持或参与多项国家自然科学基金项目，《哌嗪季铵盐类非成瘾性镇痛药物研究》获北京市科技进步二等奖，为第二完成人。教学：从事有机化学教学工作并主持多项教改项目，参编译著《杂环化学》,编写多种《有机化学》教材。曾获北京大学药学院青年教师讲课比赛一等奖，北京大学青年教师讲课比赛三等奖，主持的《基础有机化学》获北京大学医学部精品课程。
研究领域
杂环药物的设计、合成及生物活性研究；有机小分子催化及有机合成新方法的研究
近期论文
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1) Wei Zhan, Meng Tong, Ling Ji, Han Zhang, Zemei Ge, Xin Wang*, Runtao Li*. Continuous-flow synthesis of nitriles from aldehydes via Schmidt reaction. CCL, 2019, 30, 973-976.
2) Qiang Wei,Junfeng Wang, Eman A. Akam, Dawei Yin,Zemei Ge,Tieming Cheng, Xin Wang,* Anna-Liisa Brownell,*and Runtao Li* Transition Metal-Free Intermolecular C(sp2)-H Direct Amination of Furanones via a Redox Pathway. J. Org. Chem. 2019, 84, 1310-1319.
3) Wei Zhan, Ling Ji, Ze-mei Ge, Xin Wang*, Run-tao Li*. A continuous-flow synthesis of primary amides from hydrolysis of nitriles using hydrogen peroxide as oxidant. Tetrahedron 2018,74, 1527-1532.
4) Xiaolei Du, Dawei Yin, Zemei Ge, Xin Wang*, Runtao Li*. Asymmetric Michael addition reactions of pyrrolones with chalcones catalyzed by vicinal primary-diamine salts. RSC Advances, 2017,7, 24547-24550.
5) Shucheng Wang; Xuhu Huang; Zemei Ge; Xin Wang*, Runtao Li*. An efficient synthesis of sulfonated quinoline diones by copper catalyzed sulfonylation of activated alkenes with sulfonylhydrazides RSC Advances, 2016, 6: 11754-11757.
6) Shucheng Wang; Xuhu Huang; Zemei Ge; Xin Wang*, Runtao Li*. Metal-free C-3 alkylation of imidazopyridines with xanthates and convenient access to alpidem and zolpidem RSC Advances, 2016, 6(68): 63532~63535.
7) Zhushuang Bai, Ling Ji, Zemei Ge, Xin Wang*; Runtao Li.*Asymmetric Michael addition reactions of nitroalkanes to 2-furanones catalyzed by bifunctional thiourea catalysts. Org. Biomol. Chem. 2015, 13(19), 5363-5366.
8) Dawei Yin+, Wei Wang+, Yangqiu Peng, Zemei Ge, Tieming Cheng, Xin Wang*, Runtao Li*. Synthesis of furo[3,4-c]quinolin-3(1H)-one derivatives through TMG catalyzed intramolecular aza-MBH reaction based on the furanones. RSC Advances, 2015, 5, 17296-17299.
9) Yu-peng Liu, Jin-ming Liu,Xin Wang*, Tie-ming Cheng, Run-tao Li* Multicomponent reactions leading to symmetric and asymmetric multi-substituted 1,4-dihydropyridines on montmorillonite.Tetrahedron, 2013, 69(25):, 5242-5247.
10) Wei Wang, Junfeng Wang, Shuo Zhou, Qi Sun, Zemei Ge, Xin Wang* Runtao Li* An Efficient Organocatalytic Enantioselective Michael Addition of Aryl Methyl Ketones with 2-Furanone: Highly Functionalized Chiral 3,4-Substituted Lactones. Chem. Commun. 2013, 49(13): 1333-1335.
11) Xin Wang, Yaowu Sha, Zemei Ge, Wei Wang, Runtao Li*. Fragmentation patterns of novel dithiocarbamate derivatives with pharmaceutical activity under electrospray ionization tandem mass spectrometry conditions. Rapid commun. mass spectrum., 2011, 25(2): 349-354.
12) Xin Ai, Xin Wang*, Jin-ming Liu, Ze-mei Ge, Tie-ming Cheng, Run-tao Li*.An effective Aza-Michael addition of aromatic amines to electron-de？cient alkenes in alkaline Al2O3. Tetrahedron, 2010, 66 (29):5373-5377.
13) Shuai Xia, Xin Wang,* Ze-mei Ge, Tie-ming Cheng, Run-tao Li*. An Efficient Synthesis of aryldithiocarbamic acid esters from Michael addition of electron-deficient alkenes with arylamines and CS2 in solid media alkaline Al2O3 Tetrahedron, 2009, 65 (5): 1005-1009.
14) Xin Wang, Yaowu Sha, Xueling Hou, Runtao Li. Electrospray ionization tandem mass spectrometric analysis of fragmentation patterns of dithiocarbamate derivatives. Rapid commun. mass spectrum., 2006; 20: 719-722.
15) Xin Wang, Feng-Li Gao, Hong-Bin Piao, Tie-Ming Cheng, Run-Tao Li. Unique spirocyclo-piperazinium salt. Part 2: Synthesis and structure-activity relationship of dispirocyclo- piperazinium salts as analgesics. Bioorg. Med. Chem. Lett., 2003, 13:1729-1732.
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