个人简介
教育背景
1998.9-2002.7 理学学士 山东大学 药学院
2002.9-2005.7 理学硕士 沈阳药科大学 药剂学系(导师:王思玲 教授)
2005.9-2008.7 理学博士 北京大学 药剂学系(导师:张强 教授)
工作经历
2008.8-2010.5 博士后 中科院生物物理研究所(导师:梁伟 教授)
2010.6-2015.2 博士后 美国德克萨斯大学西南医学中心(导师:Jinming Gao教授)
2015.3至今 研究员,北京大学药学院
荣誉及奖励
2019 北京市“杰出青年科学基金”获得者
2017 中国药学会-赛诺菲青年生物药物奖
2016 国家“优秀青年科学基金”获得者
2015 中国药学会-中恒青年药剂学奖
2014 北京大学优秀青年人才入选者
研究领域
(1) 智能靶向纳米药物递送系统的研究
(2)基于纳米技术的肿瘤诊疗研究
(3)纳米给药系统体内转运的分子机理研究
近期论文
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Yin Q, Pan A, Chen B, Wang Z, Tang M, Yan Y, Wang YQ, Xia H, Chen W, Du H, Chen M, Fu C, Wang YN, Yuan X, Lu Z, Zhang Q, Wang YG*. Quantitative imaging of intracellular nanoparticle exposure enables prediction of nanotherapeutic efficacy. Nature Communications. 2021, 12, 2385.
Wang Z, Xia H, Chen B, Wang YQ, Yin Q, Yan Y, Zhang Q, Wang YG*. pH-amplified CRET nanoparticles for in vivo imaging of tumor metastatic lymph nodes. Angewandte Chemie International Edition. 2021, DOI: 10.1002/anie.202102044.
Yan Y, Chen B, Wang Z, Yin Q, Wang YQ, Wan F, Mo Y, Xu B, Zhang Q, Wang S*, Wang YG*. Sequential modulations of tumor vasculature and stromal barriers augment the active targeting efficacy of antibody-modified nanophotosensitizer in desmoplastic ovarian carcinoma. Advanced Science. 2021, 8, 2002253.
Du H, Zhao S, Wang YQ, Wang Z, Chen B, Yan Y, Yin Q, Liu D, Wan F, Zhang Q, Wang YG*. pH/Cathepsin B Hierarchical Responsive Nano-conjugates for Enhanced Tumor Penetration and Chemo-immunotherapy. Advanced Functional Materials. 2020, 30, 2003757.
Liu D, Chen BL, Mo Y, Wang Z, Qi T, Zhang Q, Wang YG*. Redox-Activated Porphyrin-Based Liposome Remote-Loaded with IDO Inhibitor for Synergistic Photoimmunotherapy through Induction of Immunogenic Cell Death and Blockage of IDO Pathway. Nano Letters. 2019, 19, 6964-6976.
Wang YG*, Wang CS, Li Y, Huang G, Zhao T, Ma XP, Wang ZH, White MA, Sumer BD, Gao JM*. Digitization of Endocytic pH by Hybrid Ultra-pH Sensitive Nanoprobes at Single Organelle Resolution. Advanced Materials. 2017, 29, 1603794. (*Corresponding author)
Wang YG, Zhou KJ, Huang G, Hensley C, Huang XN, Ma XP, Zhao T, Sumer BD, DeBerardinis RJ, Gao JM*. A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals. Nature Materials. 2014, 13, 204-212.